Nonmyeloablative stem cell transplantation with a haploidentical donor in a class 3 lucarelli severe thalassemia patient [1]

Bone Marrow Transplantation

Volumn 34, Issue 3, 2004, Pages 271-272

  Hongeng, S ^a   Pakakasama, S ^a   Chaisiripoomkere, W ^a   Ungkanont, A ^a   Jootar, S ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

BUSULFAN; CYCLOSPORIN; DEFEROXAMINE; FLUDARABINE; GRANULOCYTE COLONY STIMULATING FACTOR; HEMOCARE; HEMOGLOBIN; HEMOGLOBIN F; HYDROXYUREA; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; THYMOCYTE ANTIBODY;

ADULT; ANAMNESIS; BETA THALASSEMIA; BLOOD TRANSFUSION; CASE REPORT; CHELATION THERAPY; CHIMERA; DISEASE SEVERITY; DONOR; ERYTHROCYTE TRANSFUSION; FEMALE; GENOTYPE; GRAFT REJECTION; GRAFT VERSUS HOST REACTION; HAPLOTYPE; HLA SYSTEM; HOMOZYGOSITY; HUMAN; LETTER; LIVER BIOPSY; MOTHER; OUTCOMES RESEARCH; PHYSICAL EXAMINATION; PRIORITY JOURNAL; QUALITY OF LIFE; SPLENECTOMY; SPLENOMEGALY; STEM CELL TRANSPLANTATION; WHOLE BODY RADIATION;

ADOLESCENT; BETA-THALASSEMIA; BLOOD TRANSFUSION; BONE MARROW TRANSPLANTATION; BUSULFAN; FEMALE; FETAL HEMOGLOBIN; GRANULOCYTE COLONY-STIMULATING FACTOR; HEMATOPOIETIC STEM CELL MOBILIZATION; HUMANS; LIVING DONORS; MOTHERS; STEM CELL TRANSPLANTATION; TRANSPLANTATION CHIMERA; TRANSPLANTATION CONDITIONING; TREATMENT OUTCOME;

EID: 4344588894     PISSN: 02683369     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bmt.1704572     Document Type: Letter

References (9)

1. Lucarelli G, Galimberti M, Polchi P et al. Bone marrow transplantation in patients with thalassemia. N Engl J Med 1990; 322: 417-421.
2. Andreani M, Manna M, Lucarelli G et al. Persistence of mixed chimerism in patients transplanted for the treatment of thalassemia. Blood 1996; 87: 3494-3499.
3. Champlin R, Khouri I, Kornblau S et al. Reinventing bone marrow transplantation: reducing toxicity using nonmyeloablative, preparative regimens and induction of graft-versus-malignancy. Curr Opin Oncol 1999; 11: 87-95 (Transplantation 2000; 6: 309-320).
4. Hongeng S, Chuansumrit A, Hathirat P et al. Full chimerism in nonmyeloablative stem cell transplantation in a β-thalassemia major patient (class 3 Lucarelli). Bone Marrow Transplant 2003; 30: 409-410.
5. Muretto P, Angelucci E, Del Fiasco S, Lucarelli G. Reversal features of hepatic haemosiderosis and haemochromatosis in thalassemia after bone marrow transplantation. Prog Clin Biol Res 1989; 309: 299-314.
6. Krishnamurti L, Blazar BR, Wagner JE. Bone marrow transplantation without myeloablation for sickle cell disease. N Engl J Med 2001; 344: 68.
7. Gaziev D, Polchi P, Lucarelli G et al. Second marrow transplant for graft failure in patients with thalassemia. Bone Marrow Transplant 1999; 24: 1299-1306.
8. Xun CQ, Thompson JS, Jennings CD et al. Effect of total body irradiation, busulfan-cyclophosphamide, or cyclophosphamide conditioning on inflammatory cytokine release and development of acute and chronic graft-versus-host disease in H-2-incompatible transplanted SCID mice. Blood 1994; 83: 2360-2367.
9. Aversa F, Tabilio A, Velardi A et al. Treatment of high-risk leukemia with T-cell-depleted stem cells from related donors with one fully mismatched HLA haplotype. N Engl J Med 1998; 339: 1186-1193.