Clinical characteristics and prevalence of GB virus C, SEN virus, and HFE gene mutation in Japanese patients with nonalcoholic steatohepatitis

Journal of Gastroenterology

Volumn 39, Issue 7, 2004, Pages 654-660

  Yamauchi, Norihito ^a   Itoh, Yoshito ^a   Tanaka, Yasuhito ^b   Mizokami, Masashi ^b   Minami, Masahito ^a   Morita, Atsuhiro ^a   Toyama, Tetsuya ^a   Yamaguchi, Kanji ^a   Fujii, Hideki ^a   Okanoue, Takeshi ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

^b NAGOYA CITY UNIVERSITY GRADUATE SCHOOL OF MEDICAL SCIENCES   (Japan)

Author keywords

GB virus C; HFE gene mutation; Nonalcoholic steatohepatitis; SEN virus

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CHOLESTEROL; FERRITIN; HFE PROTEIN; VIRUS DNA; VIRUS RNA;

ADULT; AGE DISTRIBUTION; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY MASS; CHOLESTEROL BLOOD LEVEL; CLINICAL ARTICLE; CLINICAL FEATURE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FATTY LIVER; FEMALE; FERRITIN BLOOD LEVEL; HEPATITIS G VIRUS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; JAPAN; MALE; MUTATIONAL ANALYSIS; NONALCOHOLIC FATTY LIVER; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SEN VIRUS; SERODIAGNOSIS; SEROPREVALENCE; SEX RATIO; VIRUS INFECTION;

EID: 4344582976     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00535-003-1361-y     Document Type: Article

References (45)

1. Sanyal AJ. AGA technical review of nonalcoholic fatty liver disease. Gastroenterology 2002;123:1705-25.
2. Reid AE. Nonalcoholic steatohepatitis. Gastroenterology 2001; 121:710-23.
3. Younossi ZM, Diehl AM, Ong JP. Nonalcoholic fatty liver disease: an agenda for clinical research. Hepatology 2002;35:746-52.
4. Angulo P. Nonalcoholic fatty liver disease. N Engl J Med 2002; 346:1221-31.
5. Powell EE, Cooksley WGE, Hanson R, Searle J, Halliday JW, Powell LW. The natural history of nonalcoholic steatohepatitis: a follow-up study of 42 patients for up to 21 years. Hepatology 1990;11:74-80.
6. Teli MR, James OFW, Burt AD, Bennett MK, Day CP. The natural history of nonalcoholic fatty liver: a follow-up study. Hepatology 1995;22:1714-9.
7. Brunt EM. Nonalcoholic steatohepatitis: definition and pathology. Semin Liver Dis 2001;21:3-16.
8. Day CP, James OFW. Steatohepatitis: a tale of two "hits"? Gastroenterology 1998;114:842-5.
9. James O, Day C. Non-alcoholic steatohepatitis: another disease of affluence. Lancet 1999;353:1634-6.
10. George DK, Goldwurm S, Macdonald GA, Cowley LL, Walker NI, Ward PJ, et al. Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis. Gastroenterology 1998;114:311-8.
11. Bonkovsky HL, Jawaid Q, Tortorelli K, LeClair P, Cobb J, Lambrecht RW, et al. Non-alcoholic steatohepatitis and iron: increased prevalence of mutations of the HFE gene in non-alcoholic steatohepatitis. J Hepatol 1999;31:421-9.
12. Casaril M, Stanzial AM, Tognella P, Pantalena M, Capra F, Colombari R, et al. Role of iron load on fibrogenesis in chronic hepatitis C. Hepatogastroenterology 2000;47:220-5.
13. Raynard B, Balian A, Fallik D, Capron F, Bedossa P, Chaps J, et al. Risk factors of fibrosis in alcohol-induced liver disease. Hepatology 2002;35:635-8.
14. Linnen J, Wages J Jr, Zhang-Keck ZY, Fry KE, Krawczynski KZ, Alter H, et al. Molecular cloning and disease association of hepatitis G virus: a transfusion-transmissible agent. Science 1996; 271:505-8.
15. Simons JN, Leary TP, Dawson GJ, Pilot-Matias TJ, Muerhoff AS, Schlauder GG, et al. Isolation of novel virus-like sequences associated with human hepatitis. Nat Med 1995;1:564-9.
16. Kiyosawa K. Non-alcoholic steatohepatitis and GB virus-C/hepatitis G virus infection: is there a causal relationship? Intern Med 1997;36:236-7.
17. Nishizawa T, Okamoto H, Konishi K, Yoshizawa H, Miyakawa Y, Mayumi M. A novel DNA virus (TTV) associated with elevated transaminase levels in posttransfusion hepatitis of unknown etiology. Biochem Biophys Res Commun 1997;241:92-7.
18. Matsumoto A, Yeo AET, Shih JWK, Tanaka E, Kiyosawa K, Alter HJ. Transfusion-associated TT virus infection and its relationship to liver disease. Hepatology 1999;30:283-8.
19. Tokita H, Murai S, Kamitsukasa H, Yagura M, Harada H, Hebisawa A, et al. Influence of TT virus on the histopathological features of nonalcoholic fatty liver disease. Hepatol Res 2001;19: 197-211.
20. Primi D, Fiordalisi G, Mantero JL, Bonelli M, Olivero P, Vaglini L, et al. Identification of SENV genotypes. International patent number WO0028039 (international application published under the patent cooperation treaty). Available from URL: http://ep.espacenet.com
21. Tanaka Y, Primi D, Wang RYH, Umemura T, Yeo AET, Mizokami M, et al. Genomic and molecular evolutionary analysis of a newly identified infectious agent (SEN virus) and its relationship to the TT virus family. J Infect Dis 2001;183:359-67.
22. Umemura T, Yeo AET, Sottini A, Moratto D, Tanaka Y, Wang RYH, et al. SEN virus infection and its relationship to transfusion-associated hepatitis. Hepatology 2001;33:1303-11.
23. Brunt EM, Janney CG, DiBisceglie AM, Neuschwander-Tetri BA, Bacon BR. Nonalcoholic steatohepatitis: a proposal for grading and staging the histologic lesions. Am J Gastroenterol 1999; 94:2467-74.
24. MacSween RNM, Anthony PP, Sheuer PJ. Pathology of the liver. Edinburgh: Churchill Livingstone; 1987. p. 185.
25. Tan D, Matsumoto A, Conry-Cantilena C, Melpolder JC, Shin JWK, Leuther M, et al. Analysis of hepatitis G virus (HGV) RNA, antibody to HGV envelope protein, and risk factors for blood donors coinfected with HGV and hepatitis C virus. J Infect Dis 1999;179:1055-61.
26. Schlueter V, Schmolke S, Stark K, Hess G, Ofenloch-Haehnle B, Engel AM. Reverse transcription-PCR detection of hepatitis G virus. J Clin Microbiol 1996;34:2660-4.
27. Forns X, Tan D, Alter HJ, Purcell RH, Bukh J. Evaluation of commercially available and in-house reverse transcription-PCR assays for the detection of hepatitis G virus or GB virus C. J Clin Microbiol 1997;35:2698-702.
28. Statistics Toolbox User's Guide 1999. Natick, MA: The Mathworks Inc; 1999.
29. Pfeiffer RM, Gail MH, Brown LM. A mixture model for the distribution of IgG antibodies to Helicobacter pylori: application to studying factors that affect prevalence. J Epidemiol Biostat 1999;5:267-75.
30. Kazemi-Shirazi L, Datz C, Maier-Dobersberger T, Kaserer K, Hackl F, Polli C, et al. The relation of iron status and hemochromatosis gene mutations in patients with chronic hepatitis C. Gastroenterology 1998;116:127-34.
31. Ludwig J, Viggiano TR, McGill DB, Ott BJ. Nonalcoholic steatohepatitis: Mayo Clinic experiences with a hitherto unnamed disease. Mayo Clin Proc 1980;55:434-8.
32. Matteoni CA, Younossi ZM, Gramlich T, Boparai N, Liu YC, McCullough AJ. Nonalcoholic fatty liver disease: a spectrum of clinical and pathological severity. Gastroenterology 1999;116: 1413-9.
33. Bacon BR, Farahvash MJ, Janney CG, Neuschwander-Tetri BA. Nonalcoholic steatohepatitis: an expanded clinical entity. Gastroenterology 1994;107:1103-9.
34. Angulo P, Keach J, Batts K, Linder KD. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 1999;30:1356-62.
35. Mendler M, Turlin B, Moirand R, Jounaolle A, Sapey T, Guyader D, et al. Insulin resistance-associated hepatic iron overload. Gastroenterology 1999;117:1155-63.
36. Younossi ZM, Gramlich T, Bacon BR, Matteoni CA, Boparai N, O'Neill R, et al. Hepatic iron and nonalcoholic fatty liver disease. Hepatology 1999;30:847-50.
37. Sohda T, Yanai J, Soejima H, Tamura K. Frequencies in the Japanese population of HFE gene mutations. Biochem Genet 1999;37:63-8.
38. Chitturi S, Abeygunasekera S, Farrell GC, Holmes-Walker J, Hui JM, Fung C, et al. NASH and insulin resistance: insulin hypersecretion and specific association with the insulin resistance syndrome. Hepatology 2002;35:373-9.
39. Rogers DW, Lee CH, Pound DC, Kumar S, Cummings OW, Lumeng L. Hepatitis C virus does not cause nonalcoholic steatohepatitis. Dig Dis Sci 1992;37:1644-7.
40. Nakatsuji Y, Shih JW, Tanaka E, Kiyosawa K, Wages J Jr, Kim JP, et al. Prevalence and disease association of hepatitis G virus infection in Japan. J Viral Hepat 1996;3:307-16.
41. Mikuni M, Moriyama M, Tanaka N, Abe K, Arakawa Y. SEN virus infection does not affect the progression of non-A to -E liver disease. J Med Virol 2002;67:624-9.
42. Loguercio C, Girolamo V, Sio I, Tuccillo C, Ascione A, Baldi F, et al. Non-alcoholic fatty liver disease in an area of southern Italy: main clinical, histological, and pathophysiological aspects. J Hepatol 2001;35:568-74.
43. Sumida Y, Nakashima T, Yoh, T, Furutani M, Hirohama A, Okanoue T, et al. Serum thioredoxin levels as a predictor of steatohepatitis in patients with nonalcoholic fatty liver disease. J Hepatol 2003;38:32-8.
44. Powell EE, Kroon PA. Liver, lipoproteins and disease: II. Clinical relevance of disordered cholesterol metabolism in liver disease. J Gastroenterol Hepatol 1992;7:225-31.
45. Cicognani C, Malavolti M, Morselli-Labate AM, Zamboni L, Sama C, Barbara L. Serum lipid and lipoprotein patterns in patients with liver cirrhosis and chronic active hepatitis. Arch Intern Med 1997;157:792-6.