Coordinated expression of MUC2 and CDX-2 in mucinous carcinomas of the lung can be explained by the role of CDX-2 as transcriptional regulator of MUC2 [3]

American Journal of Surgical Pathology

Volumn 28, Issue 9, 2004, Pages 1254-1255

  Mesquita, Patrícia ^a   Almeida, Raquel ^a   Van Seuningen, Isabelle ^b   David, Leonor ^c  

^a UNIVERSITY OF PORTO   (Portugal)

^b INSERM   (France)

^c University of Porto   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

HOMEODOMAIN PROTEIN; MUCIN 2; TRANSCRIPTION FACTOR CDX1; TRANSCRIPTION FACTOR CDX2; UNCLASSIFIED DRUG;

GENE EXPRESSION; GENE FUNCTION; GENE IDENTIFICATION; GENETIC TRANSCRIPTION; GOBLET CELL; HOMEOBOX; HUMAN; INTESTINE METAPLASIA; LETTER; LUNG CARCINOMA; MOLECULAR MECHANICS; MUCINOUS CARCINOMA; PROMOTER REGION; STOMACH CARCINOMA; TRANSCRIPTION REGULATION;

ADENOCARCINOMA, MUCINOUS; HOMEODOMAIN PROTEINS; HUMANS; LUNG NEOPLASMS; MUCINS; TRANS-ACTIVATORS; TRANSCRIPTION, GENETIC;

EID: 4344561195     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.pas.0000135517.50095.7f     Document Type: Letter

References (3)

1. Almeida R, Silva E, Santos-Silva F, et al. Expression of intestine-specific transcription factors, CDX1 and CDX2, in intestinal metaplasia and gastric carcinomas. J Pathol. 2003;199: 36-40.
2. Mesquita P, Jonckheere N, Almeida, R, et al. Human MUC2 mucin gene is transcriptionally regulated by Cdx homeodomain proteins in gastrointestinal carcinoma cell lines. J Biol Chem. 2003;278:51549-51556.
3. Rossi G, Murer B, Cavazza A, et al. Primary mucinous (so-called colloid) carcinomas of the lung: a clinicopathologic and immunohistochemical study with special reference to CDX-2 homeobox gene and MUC2 expression. Am J Surg Pathol. 2004;28:442-452.