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Volumn 57, Issue 6, 2008, Pages 833-847

CD4+ T-cell recognition of human 5T4 oncofoetal antigen: Implications for initial depletion of CD25+ T cells

Author keywords

5T4 oncofoetal antigen; CD25+ cell depletion; CD4+ T cells; Dendritic cells; T regulatory cells

Indexed keywords

ONCOFETAL ANTIGEN;

EID: 43349105088     PISSN: 03407004     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00262-007-0419-8     Document Type: Article
Times cited : (20)

References (57)
  • 3
    • 0035451392 scopus 로고    scopus 로고
    • From cancer genomics to cancer immunotherapy: Toward second-generation tumor antigens
    • Schultze JL, Vonderheide RH (2001) From cancer genomics to cancer immunotherapy: toward second-generation tumor antigens. Trends Immunol 22:516-523
    • (2001) Trends Immunol , vol.22 , pp. 516-523
    • Schultze, J.L.1    Vonderheide, R.H.2
  • 4
    • 0025886953 scopus 로고
    • Adoptive T cell therapy of tumors: Mechanisms operative in the recognition and elimination of tumor cells
    • Greenberg PD (1991) Adoptive T cell therapy of tumors: mechanisms operative in the recognition and elimination of tumor cells. Adv Immunol 49:281-355
    • (1991) Adv Immunol , vol.49 , pp. 281-355
    • Greenberg, P.D.1
  • 5
    • 0037821557 scopus 로고    scopus 로고
    • P53(110-124)-specific human CD4+ T-helper cells enhance in vitro generation and antitumor function of tumor-reactive CD8+ T cells
    • Chikamatsu K, Albers A, Stanson J, Kwok WW, Appella E, Whiteside TL, DeLeo AB (2003) P53(110-124)-specific human CD4+ T-helper cells enhance in vitro generation and antitumor function of tumor-reactive CD8+ T cells. Cancer Res 63:3675-3681
    • (2003) Cancer Res , vol.63 , pp. 3675-3681
    • Chikamatsu, K.1    Albers, A.2    Stanson, J.3    Kwok, W.W.4    Appella, E.5    Whiteside, T.L.6    Deleo, A.B.7
  • 6
    • 0025060715 scopus 로고
    • Isolation and characterization of 5T4, a tumour-associated antigen
    • Hole N, Stern PL (1990) Isolation and characterization of 5T4, a tumour-associated antigen. Int J Cancer 45:179-184
    • (1990) Int J Cancer , vol.45 , pp. 179-184
    • Hole, N.1    Stern, P.L.2
  • 7
    • 0028340558 scopus 로고
    • Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats
    • Myers KA, Rahi-Saund V, Davison MD, Young JA, Cheater AJ, Stern PL (1994) Isolation of a cDNA encoding 5T4 oncofetal trophoblast glycoprotein. An antigen associated with metastasis contains leucine-rich repeats. J Biol Chem 269:9319-9324
    • (1994) J Biol Chem , vol.269 , pp. 9319-9324
    • Myers, K.A.1    Rahi-Saund, V.2    Davison, M.D.3    Young, J.A.4    Cheater, A.J.5    Stern, P.L.6
  • 11
    • 0026442540 scopus 로고
    • The expression of 5T4 antigen in colorectal and gastric carcinoma
    • Starzynska T, Rahi V, Stern PL (1992) The expression of 5T4 antigen in colorectal and gastric carcinoma. Br J Cancer 66:867-869
    • (1992) Br J Cancer , vol.66 , pp. 867-869
    • Starzynska, T.1    Rahi, V.2    Stern, P.L.3
  • 14
    • 27144440353 scopus 로고    scopus 로고
    • Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: A potential target for T-cell-based immunotherapy
    • Griffiths RW, Gilham DE, Dangoor A, Ramani V, Clarke NW, Stern PL, Hawkins RE (2005) Expression of the 5T4 oncofoetal antigen in renal cell carcinoma: a potential target for T-cell-based immunotherapy. Br J Cancer 93:670-677
    • (2005) Br J Cancer , vol.93 , pp. 670-677
    • Griffiths, R.W.1    Gilham, D.E.2    Dangoor, A.3    Ramani, V.4    Clarke, N.W.5    Stern, P.L.6    Hawkins, R.E.7
  • 15
    • 33745223435 scopus 로고    scopus 로고
    • Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: A phase I/II trial
    • Harrop R, Connolly N, Redchenko I, Valle J, Saunders M, Ryan MG, Myers KA, Drury N, Kingsman SM, Hawkins RE, Carroll MW (2006) Vaccination of colorectal cancer patients with modified vaccinia Ankara delivering the tumor antigen 5T4 (TroVax) induces immune responses which correlate with disease control: a phase I/II trial. Clin Cancer Res 12:3416-3424
    • (2006) Clin Cancer Res , vol.12 , pp. 3416-3424
    • Harrop, R.1    Connolly, N.2    Redchenko, I.3    Valle, J.4    Saunders, M.5    Ryan, M.G.6    Myers, K.A.7    Drury, N.8    Kingsman, S.M.9    Hawkins, R.E.10    Carroll, M.W.11
  • 16
    • 1842848097 scopus 로고    scopus 로고
    • Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors
    • Mulryan K, Ryan MG, Myers KA, Shaw D, Wang W, Kingsman SM, Stern PL, Carroll MW (2002) Attenuated recombinant vaccinia virus expressing oncofetal antigen (tumor-associated antigen) 5T4 induces active therapy of established tumors. Mol Cancer Ther 1:1129-1137
    • (2002) Mol Cancer Ther , vol.1 , pp. 1129-1137
    • Mulryan, K.1    Ryan, M.G.2    Myers, K.A.3    Shaw, D.4    Wang, W.5    Kingsman, S.M.6    Stern, P.L.7    Carroll, M.W.8
  • 21
    • 0035180065 scopus 로고    scopus 로고
    • Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: Their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance
    • Sakaguchi S, Sakaguchi N, Shimizu J, Yamazaki S, Sakihama T, Itoh M, Kuniyasu Y, Nomura T, Toda M, Takahashi T (2001) Immunologic tolerance maintained by CD25+ CD4+ regulatory T cells: their common role in controlling autoimmunity, tumor immunity, and transplantation tolerance. Immunol Rev 182:18-32
    • (2001) Immunol Rev , vol.182 , pp. 18-32
    • Sakaguchi, S.1    Sakaguchi, N.2    Shimizu, J.3    Yamazaki, S.4    Sakihama, T.5    Itoh, M.6    Kuniyasu, Y.7    Nomura, T.8    Toda, M.9    Takahashi, T.10
  • 22
    • 0036597371 scopus 로고    scopus 로고
    • CD4+ CD25+ suppressor T cells: More questions than answers
    • Shevach EM (2002) CD4+ CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2:389-400
    • (2002) Nat Rev Immunol , vol.2 , pp. 389-400
    • Shevach, E.M.1
  • 23
    • 0037262280 scopus 로고    scopus 로고
    • The role of regulatory T cells in controlling immunologic self-tolerance
    • Takahashi T, Sakaguchi S (2003) The role of regulatory T cells in controlling immunologic self-tolerance. Int Rev Cytol 225:1-32
    • (2003) Int Rev Cytol , vol.225 , pp. 1-32
    • Takahashi, T.1    Sakaguchi, S.2
  • 24
    • 0033168037 scopus 로고    scopus 로고
    • Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody
    • Onizuka S, Tawara I, Shimizu J, Sakaguchi S, Fujita T, Nakayama E (1999) Tumor rejection by in vivo administration of anti-CD25 (interleukin-2 receptor alpha) monoclonal antibody. Cancer Res 59:3128-3133
    • (1999) Cancer Res , vol.59 , pp. 3128-3133
    • Onizuka, S.1    Tawara, I.2    Shimizu, J.3    Sakaguchi, S.4    Fujita, T.5    Nakayama, E.6
  • 25
    • 0033571105 scopus 로고    scopus 로고
    • Induction of tumor immunity by removing CD25+CD4+ T cells: A common basis between tumor immunity and autoimmunity
    • Shimizu J, Yamazaki S, Sakaguchi S (1999) Induction of tumor immunity by removing CD25+CD4+ T cells: a common basis between tumor immunity and autoimmunity. J Immunol 163:5211-5218
    • (1999) J Immunol , vol.163 , pp. 5211-5218
    • Shimizu, J.1    Yamazaki, S.2    Sakaguchi, S.3
  • 26
    • 0035903324 scopus 로고    scopus 로고
    • Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses
    • Sutmuller RP, van Duivenvoorde LM, van Elsas A, Schumacher TN, Wildenberg ME, Allison JP, Toes RE, Offringa R, Melief CJ (2001) Synergism of cytotoxic T lymphocyte-associated antigen 4 blockade and depletion of CD25(+) regulatory T cells in antitumor therapy reveals alternative pathways for suppression of autoreactive cytotoxic T lymphocyte responses. J Exp Med 194:823-832
    • (2001) J Exp Med , vol.194 , pp. 823-832
    • Sutmuller, R.P.1    Van Duivenvoorde, L.M.2    Van Elsas, A.3    Schumacher, T.N.4    Wildenberg, M.E.5    Allison, J.P.6    Toes, R.E.7    Offringa, R.8    Melief, C.J.9
  • 27
    • 0035806244 scopus 로고    scopus 로고
    • Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood
    • Dieckmann D, Plottner H, Berchtold S, Berger T, Schuler G (2001) Ex vivo isolation and characterization of CD4(+)CD25(+) T cells with regulatory properties from human blood. J Exp Med 193:1303-1310
    • (2001) J Exp Med , vol.193 , pp. 1303-1310
    • Dieckmann, D.1    Plottner, H.2    Berchtold, S.3    Berger, T.4    Schuler, G.5
  • 28
    • 0037385330 scopus 로고    scopus 로고
    • Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
    • Fontenot JD, Gavin MA, Rudensky AY (2003) Foxp3 programs the development and function of CD4+CD25+ regulatory T cells. Nat Immunol 4:330-336
    • (2003) Nat Immunol , vol.4 , pp. 330-336
    • Fontenot, J.D.1    Gavin, M.A.2    Rudensky, A.Y.3
  • 31
    • 0023818391 scopus 로고
    • A 72 kD trophoblast glycoprotein defined by a monoclonal antibody
    • Hole N, Stern PL (1988) A 72 kD trophoblast glycoprotein defined by a monoclonal antibody. Br J Cancer 57:239-246
    • (1988) Br J Cancer , vol.57 , pp. 239-246
    • Hole, N.1    Stern, P.L.2
  • 32
    • 14744268262 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2
    • Antony PA, Restifo NP (2005) CD4+CD25+ T regulatory cells, immunotherapy of cancer, and interleukin-2. J Immunother 28:120-128
    • (2005) J Immunother , vol.28 , pp. 120-128
    • Antony, P.A.1    Restifo, N.P.2
  • 35
    • 33750797738 scopus 로고    scopus 로고
    • The wild-type sequence (wt) p53(25-35) peptide induces HLA-DR7 and HLA-DR11-restricted CD4+ Th cells capable of enhancing the ex vivo expansion and function of anti-wt p53(264-272) peptide CD8+ T cells
    • Ito D, Albers A, Zhao YX, Visus C, Appella E, Whiteside TL, DeLeo AB (2006) The wild-type sequence (wt) p53(25-35) peptide induces HLA-DR7 and HLA-DR11-restricted CD4+ Th cells capable of enhancing the ex vivo expansion and function of anti-wt p53(264-272) peptide CD8+ T cells. J Immunol 177:6795-6803
    • (2006) J Immunol , vol.177 , pp. 6795-6803
    • Ito, D.1    Albers, A.2    Zhao, Y.X.3    Visus, C.4    Appella, E.5    Whiteside, T.L.6    Deleo, A.B.7
  • 36
    • 30144432417 scopus 로고    scopus 로고
    • Initial depletion of regulatory T cells: The missing solution to preserve the immune functions of T lymphocytes designed for cell therapy
    • Mesel-Lemoine M, Cherai M, Le Gouvello S, Guillot M, Leclercq V, Klatzmann D, Thomas-Vaslin V, Lemoine FM (2006) Initial depletion of regulatory T cells: the missing solution to preserve the immune functions of T lymphocytes designed for cell therapy. Blood 107:381-388
    • (2006) Blood , vol.107 , pp. 381-388
    • Mesel-Lemoine, M.1    Cherai, M.2    Le Gouvello, S.3    Guillot, M.4    Leclercq, V.5    Klatzmann, D.6    Thomas-Vaslin, V.7    Lemoine, F.M.8
  • 37
    • 0347785480 scopus 로고    scopus 로고
    • Control of regulatory T cell development by the transcription factor Foxp3
    • Hori S, Nomura T, Sakaguchi S (2003) Control of regulatory T cell development by the transcription factor Foxp3. Science 299:1057-1061
    • (2003) Science , vol.299 , pp. 1057-1061
    • Hori, S.1    Nomura, T.2    Sakaguchi, S.3
  • 40
    • 2142645808 scopus 로고    scopus 로고
    • Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7
    • Fantini MC, Becker C, Monteleone G, Pallone F, Galle PR, Neurath MF (2004) Cutting edge: TGF-beta induces a regulatory phenotype in CD4+CD25- T cells through Foxp3 induction and down-regulation of Smad7. J Immunol 172:5149-5153
    • (2004) J Immunol , vol.172 , pp. 5149-5153
    • Fantini, M.C.1    Becker, C.2    Monteleone, G.3    Pallone, F.4    Galle, P.R.5    Neurath, M.F.6
  • 43
    • 35448930435 scopus 로고    scopus 로고
    • Induction of FOXP3 expression in naive human CD4+FOXP3- T cells by T cell receptor stimulation is TGF{beta}-dependent but does not confer a regulatory phenotype
    • 8
    • Tran DQ, Ramsey H, Shevach EM (2007) Induction of FOXP3 expression in naive human CD4+FOXP3- T cells by T cell receptor stimulation is TGF{beta}-dependent but does not confer a regulatory phenotype. Blood 110(8):2983-2990
    • (2007) Blood , vol.110 , pp. 2983-2990
    • Tran, D.Q.1    Ramsey, H.2    Shevach, E.M.3
  • 45
    • 13444263401 scopus 로고    scopus 로고
    • Depletion of CD25+ cells from human T-cell enriched fraction eliminates immunodominance during priming with dendritic cells genetically modified to express a secreted protein
    • Mincheff M, Zoubak S, Altankova I, Tchakarov S, Pogribnyy P, Makogonenko Y, Botev C, Meryman HT (2005) Depletion of CD25+ cells from human T-cell enriched fraction eliminates immunodominance during priming with dendritic cells genetically modified to express a secreted protein. Cancer Gene Ther 12:185-197
    • (2005) Cancer Gene Ther , vol.12 , pp. 185-197
    • Mincheff, M.1    Zoubak, S.2    Altankova, I.3    Tchakarov, S.4    Pogribnyy, P.5    Makogonenko, Y.6    Botev, C.7    Meryman, H.T.8
  • 46
    • 10844252294 scopus 로고    scopus 로고
    • Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
    • Fehervari Z, Sakaguchi S (2004) Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells. Int Immunol 16:1769-1780
    • (2004) Int Immunol , vol.16 , pp. 1769-1780
    • Fehervari, Z.1    Sakaguchi, S.2
  • 47
    • 2442655250 scopus 로고    scopus 로고
    • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
    • Yang Y, Huang CT, Huang X, Pardoll DM (2004) Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat Immunol 5:508-515
    • (2004) Nat Immunol , vol.5 , pp. 508-515
    • Yang, Y.1    Huang, C.T.2    Huang, X.3    Pardoll, D.M.4
  • 49
    • 30744442099 scopus 로고    scopus 로고
    • Effect of CD4+CD25+ and CD4+CD25- T regulatory cells on the generation of cytolytic T cell response to a self but human tumor-associated epitope in vitro
    • Chattopadhyay S, Mehrotra S, Chhabra A, Hegde U, Mukherji B, Chakraborty NG (2006) Effect of CD4+CD25+ and CD4+CD25- T regulatory cells on the generation of cytolytic T cell response to a self but human tumor-associated epitope in vitro. J Immunol 176:984-990
    • (2006) J Immunol , vol.176 , pp. 984-990
    • Chattopadhyay, S.1    Mehrotra, S.2    Chhabra, A.3    Hegde, U.4    Mukherji, B.5    Chakraborty, N.G.6
  • 50
    • 4143066714 scopus 로고    scopus 로고
    • Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors
    • Hsieh CS, Liang Y, Tyznik AJ, Self SG, Liggitt D, Rudensky AY (2004) Recognition of the peripheral self by naturally arising CD25+ CD4+ T cell receptors. Immunity 21:267-277
    • (2004) Immunity , vol.21 , pp. 267-277
    • Hsieh, C.S.1    Liang, Y.2    Tyznik, A.J.3    Self, S.G.4    Liggitt, D.5    Rudensky, A.Y.6
  • 52
    • 23044463715 scopus 로고    scopus 로고
    • CD4+ CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients
    • Nishikawa H, Jager E, Ritter G, Old LJ, Gnjatic S (2005) CD4+ CD25+ regulatory T cells control the induction of antigen-specific CD4+ helper T cell responses in cancer patients. Blood 106:1008-1011
    • (2005) Blood , vol.106 , pp. 1008-1011
    • Nishikawa, H.1    Jager, E.2    Ritter, G.3    Old, L.J.4    Gnjatic, S.5
  • 56
    • 0036137241 scopus 로고    scopus 로고
    • ProPred: Prediction of HLA-DR binding sites
    • Singh H, Raghava GP (2001) ProPred: prediction of HLA-DR binding sites. Bioinformatics 17:1236-1237
    • (2001) Bioinformatics , vol.17 , pp. 1236-1237
    • Singh, H.1    Raghava, G.P.2
  • 57
    • 5444249860 scopus 로고    scopus 로고
    • Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles
    • Reche PA, Glutting JP, Zhang H, Reinherz EL (2004) Enhancement to the RANKPEP resource for the prediction of peptide binding to MHC molecules using profiles. Immunogenetics 56:405-419
    • (2004) Immunogenetics , vol.56 , pp. 405-419
    • Reche, P.A.1    Glutting, J.P.2    Zhang, H.3    Reinherz, E.L.4


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