Superficial exudates of neutrophils prevent invasion of Bacillus anthracis bacilli into abraded skin of resistant mice

International Journal of Experimental Pathology

Volumn 89, Issue 3, 2008, Pages 180-187

  Hahn, Beth L ^b   Bischof, Timothy S ^b   Sohnle, Peter G ^a  

^a CLEMENT J ZABLOCKI VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b NONE

Author keywords

Bacillus anthracis; Cutaneous anthrax; Neutrophils

Indexed keywords

CYCLOPHOSPHAMIDE;

ANALYTIC METHOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BACILLUS ANTHRACIS; BACTERIAL INFECTION; BACTERIAL STRAIN; CONTROLLED STUDY; FEMALE; IMMUNE RESPONSE; INFLAMMATORY CELL; MALE; MICROBIAL ACTIVITY; MOUSE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; SKIN BIOPSY; SKIN CONDUCTANCE;

ANIMALS; ANTHRAX; BACILLUS ANTHRACIS; EXUDATES AND TRANSUDATES; IMMUNITY, NATURAL; MICE; MICE, INBRED STRAINS; NEUTROPHILS; SKIN; SKIN DISEASES, BACTERIAL; VIRULENCE;

EID: 43349104043     PISSN: 09599673     EISSN: 13652613     Source Type: Journal    
DOI: 10.1111/j.1365-2613.2008.00584.x     Document Type: Article

References (24)

1. Akiyama H., Huh W.K., Yamasaki O., Oono T., Iwatsuki K. (2002) Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in mouse skin - does S. aureus generally produce a biofilm on damaged skin? Br. J. Dermatol. 147, 879 885.
2. Bischof T.S., Hahn B.L., Sohnle P.G. (2007a) Experimental cutaneous Bacillus anthracis infections in hairless HRS/J mice. Int. J. Exp. Pathol. 88, 75 84.
3. Bischof T.S., Hahn B.L., Sohnle P.G. (2007b) Characteristics of spore germination in a mouse model of cutaneous anthrax. J. Infect. Dis. 195, 888 894.
4. Cote C.K., Van Rooijen N., Welkos S.L. (2006) Roles of macrophages and neutrophils in the early host response to Bacillus anthracis spores in a mouse model of infection. Infect. Immun. 74, 469 480.
5. Dixon T.C., Meselson M., Guillemin J., Hanna P.C. (1999) Anthrax. N. Engl. J. Med. 341, 815 826.
6. Dufour P., Gillet Y., Bes M. et al. (2002) Community-acquired methicillin-resistant Staphylococcus aureus infections in France - emergence of a single clone that produces Panton-Valentine leukocidin. Clin. Infect. Dis. 35, 819 824.
7. During R.L., Li W., Hao B. et al. (2005) Anthrax lethal toxin paralyzes neutrophil actin-based motility. J. Infect. Dis. 192, 837 845.
8. Gladstone G.P. Van Heyningen W.E. (1957) Staphylococcal leucocidins. Br. J. Exp. Pathol. 38, 123 137
9. Hachisuka Y. (1969) Germination of B. anthracis spores in the peritoneal cavity of rats and establishment of anthrax. Japan J. Microbiol. 13, 199 207.
10. Hahn B.L., Sharma S., Sohnle P.G. (2005) Analysis of epidermal entry in experimental cutaneous Bacillus anthracis infections in mice. J. Lab. Clin. Med. 146, 95 102.
11. Hanna P.C. Ireland J.A.W. (1999) Understanding Bacillus anthracis pathogenesis. Trends Microbiol. 7, 180 182.
12. Kimyai-Asadi A., Jih M.H., Freedberg I.M. (2003) Epidermal cell kinetics, epidermial differentiation, and keratinization. In: Fitzpatrick's Dermatology in Clinical Medicine, 6th edn, pp. 89 98 (eds I.M. Freedberg, A.Z. Eisen, K. Wolff, K.F. Austen, L.A. Goldsmith, S.I. Katz New York: McGraw-Hill.
13. Koivuranta-Vaara P. (1985) Neutrophil migration in vivo - analysis of a skin window technique. J. Immunol. Methods 79, 71 78.
14. Kugelberg E., Norstrom T., Petersen T.K., Duvold T., Andersson D.I., Hughes D. (2005) Establishment of a superficial skin infection model in mice by using Staphylococcus aureus and Streptococcus pyogenes. Antimicrob. Agents Chemother. 49, 3435 341.
15. Mayer-Scholl A., Hurwitz R., Brinkmann V. et al. (2005) Human neutrophils kill Bacillus anthracis. PLoS Pathogens 1, 179 186.
16. Sohnle P.G. Hahn B.L. (1989) Effect of immunosuppression on epidermal defenses in a murine model of cutaneous candidiasis. J. Lab. Clin. Med. 113, 700 707.
17. Spinola S., Wild M.L.M., Apicella M.A., Gaspari A.A., Campagnari A.A. (1994) Experimental human infection with Haemophilus ducreyi. J. Infect. Dis. 169, 1146 1150.
18. Spinola S.M., Orazi A., Arno J.N. et al. (1996) Haemophilus ducreyi elicits a cutaneous infiltrate of CD4 cells during experimental human infection. J. Infect. Dis. 173, 394 402.
19. Tsuruta D., Green K.J., Getsios S., Jones J.C.R. (2002) The barrier function of skin - how to keep a tight lid on water loss. Trends Cell Biol. 12, 355 357.
20. Wandall J.H. (1980) Leucocyte mobilization to skin lesions. Acta Pathol. Microbiol. Scand. 88, 255 261.
21. Welkos S.L. Friedlander A.M. (1988) Pathogenesis and genetic control of resistance to the Sterne strain of Bacillus anthracis. Microb. Pathogen. 4, 53 69.
22. Welkos S.L., Keener T.J., Gibbs P.H. (1986) Differences in susceptibility of inbred mice to Bacillus anthracis. Infect. Immun. 51, 795 800.
23. Welkos S.L., Trotter R.W., Becker D.M., Nelson G.O. (1989) Resistance to the Sterne strain of B. anthracis - phagocytic cell responses of resistant and susceptible mice. Microb. Pathogen. 7, 15 35.
24. Yee J., Giannias B., Kapadia B., Chartrand L., Christou N.V. (1994) Exudative neutrophils - modulation of microbicidal function in the inflammatory microenvironment. Arch. Surg. 129, 99 105.