Cloning of the koi herpesvirus genome as an infectious bacterial artificial chromosome demonstrates that disruption of the thymidine kinase locus induces partial attenuation in Cyprinus carpio koi

Journal of Virology

Volumn 82, Issue 10, 2008, Pages 4955-4964

  Costes, B ^a   Fournier, G ^a   Michel, B ^a   Delforge, C ^a   Stalin Raj, V ^a   Dewals, B ^a   Gillet, L ^a   Drion, P ^a   Body, A ^b   Schynts, F ^b   Lieffrig, F ^b   Vanderplasschen, A ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b CER   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CRE RECOMBINASE; DNA FRAGMENT; THYMIDINE KINASE; VIRULENCE FACTOR;

ANIMAL CELL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CARP; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME RELEASE; GENE CASSETTE; GENE DISRUPTION; GENE LOCUS; GENE SEQUENCE; GENETIC TRANSFECTION; GENOME; HERPES VIRUS; IN VITRO STUDY; IN VIVO STUDY; KOI HERPESVIRUS; LOXP SITE; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PLASMID; PRIORITY JOURNAL; PROKARYOTE; VIRION; VIRUS RECOMBINANT; WILD TYPE; ANIMAL; CELL CULTURE; GENE DELETION; GENETICS; GENOMIC INSTABILITY; HERPES VIRUS INFECTION; PATHOGENICITY; PHYSIOLOGY; SURVIVAL; VIROLOGY; VIRUS REPLICATION;

BACTERIA (MICROORGANISMS); COPROSMA KAUENSIS; CYPRINIDAE; CYPRINUS CARPIO; KOI HERPESVIRUS; PROKARYOTA;

ANIMALS; CARPS; CELLS, CULTURED; CHROMOSOMES, ARTIFICIAL, BACTERIAL; CLONING, MOLECULAR; GENE DELETION; GENOMIC INSTABILITY; HERPESVIRIDAE; HERPESVIRIDAE INFECTIONS; SURVIVAL ANALYSIS; THYMIDINE KINASE; TRANSFECTION; VIRULENCE FACTORS; VIRUS REPLICATION;

EID: 43249130523     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00211-08     Document Type: Article

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