Effects of astragalus on renal tubulointerestitial lesions and expression of NF-κB and MCP-1 in renal tissues in rat experimental IgA nephropathy

Chinese Journal of Contemporary Pediatrics

Volumn 10, Issue 2, 2008, Pages 173-178

  Zhang, Guo Zhen ^a   Wu, Xiao Chuan ^a   Peng, Xiao Jie ^a   Yi, Zhu Wen ^a   Mo, Shuan Hong ^a   Tan, Hang ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Astragalus; IgA nephropathy; Monocyte chemotactic protein 1; NF B; Rats; Renal tubulointerestitial lesion

Indexed keywords

ACETYLGLUCOSAMINIDASE; ASTRAGALUS EXTRACT; BOVINE SERUM ALBUMIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOCHEMISTRY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFECT; ERYTHROCYTE COUNT; IMMUNOGLOBULIN A NEPHROPATHY; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULE DISORDER; NONHUMAN; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; QUANTITATIVE ANALYSIS; RANDOMIZATION; RAT; SPRAGUE DAWLEY RAT; STATISTICAL SIGNIFICANCE; TREATMENT DURATION;

ANIMALS; ASTRAGALUS PLANT; CHEMOKINE CCL2; GLOMERULONEPHRITIS, IGA; IMMUNOHISTOCHEMISTRY; KIDNEY TUBULES; RATS; RATS, SPRAGUE-DAWLEY; TRANSCRIPTION FACTOR RELA;

EID: 43249124733     PISSN: 10088830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (19)

1. Chinese source.
2. Chinese source.
3. Chinese source.
4. Donadio JV, Grande JP. IgA nephropathy [J]. N Engl J Med, 2002, 347(10): 738-748.
5. Li L. End-stage renal disease in China [J]. Kidney Int, 1996, 49 (1):287-301.
6. Bogenschutz O, Bohle A, Batz C, Wehrmann M, Pressler H, Kendziorra H, et al. IgA nephritis: on the importance of morphological and clinical parameters in the long-term prognosis of 239 patients [J]. Am J Nephrol, 1990, 10(2):137-147.
7. Chinese source.
8. Baeuerle PA. The inducible transcription activator NF-κB: regulation by distinct protein subunits[J]. Biochim Biophy Acta, 1991, 1072(2):63-80.
9. Baldwin AS Jr. The NF-kappa B and I kappa B proteins: new discoveries and insights[J]. Annu Rev Immunol, 1996, 14: 649-683.
10. Sakurai H, Hisada Y, UenoM, Suqiura M, Kawashima K, Suqita T. Activation of transcription factor NF-κB in experimental glomerulonephritis in rats[J]. Biochim Biophys Acta, 1996, 1316(2): 132-138.
11. Wang Y, Chen J, Chen L, Tay YC, Rangan GK, Harris DC. Induction of monocyte chemoattractant protein-1 in proximal tubule cells by urinary protein[J]. J Am Soc Nephrol, 1997, 8(10): 1537-1545.
12. Chinese source.
13. Wang SN, Hirschberg R. Growth factor ultrafiltration in experimental diabetic nephropathy contributes to interstitiall fibrosis[J]. Am J Physiol Renal Physiol, 2000, 278(3):554-560.
14. Chinese source.
15. Chinese source.
16. Chinese source.
17. Chinese source.
18. Chinese source.
19. Chinese source.