Effect of column temperature on enantioseparation of dihydropyrimidinones using alcohol solvated Chiralpak AS and AS-H columns

Journal of Separation Science

Volumn 31, Issue 6-7, 2008, Pages 1027-1033

  Wang, Fang ^a   Han, Jun ^a   Yeung, David ^a   Semin, David ^a   Cheetham, Janet ^a  

^a AMGEN INC   (United States)

Author keywords

Chiralpak AS and AS H columns; Column temperature programs; Dihydropyrimidinone (DHP) compounds; HPLC enantioseparation; Step temperature program

Indexed keywords

ALCOHOLS; CHROMATOGRAPHIC ANALYSIS; SEPARATION; THERMAL EFFECTS;

CHIRALPAK; COLUMN TEMPERATURE; DIHYDROPYRIMIDINONE COMPOUNDS; ENANTIOSEPARATION; STEP TEMPERATURE;

ORGANIC COMPOUNDS;

2 BUTANOL; ALCOHOL; BUTANOL; DIHYROPYRIMIDINONE DERIVATIVE; ISOBUTANOL; PROPANOL; PYRIMIDINONE DERIVATIVE; TERT BUTYL ALCOHOL;

ARTICLE; CHEMICAL ANALYSIS; CHEMICAL REACTION KINETICS; COLUMN CHROMATOGRAPHY; CONCENTRATION RESPONSE; CONTROLLED STUDY; COOLING; HEAT SENSITIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHASE TRANSITION; PRIORITY JOURNAL; SEPARATION TECHNIQUE; SOLVATION; TEMPERATURE ACCLIMATIZATION; TEMPERATURE STRESS;

EID: 43249123203     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200700482     Document Type: Article

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