Expression of VP1 protein in the milk of transgenic mice: A potential oral vaccine protects against enterovirus 71 infection

Vaccine

Volumn 26, Issue 23, 2008, Pages 2882-2889

  Chen, Hsiao Ling ^a   Huang, Jiun Yan ^b   Chu, Te Wei ^b   Tsai, Tung Chou ^b   Hung, Che Ming ^b   Lin, Chih Cheng ^b   Liu, Fang Chueh ^b   Wang, Li Chung ^b,c   Chen, Yi Ju ^b,c   Lin, Ming Fong ^b,d   Chen, Chuan Mu ^b  

^a DA YEH UNIVERSITY   (Taiwan)

^b NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^c TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^d TAICHUNG HOSPITAL   (Taiwan)

Author keywords

Animal model; Antiviral infection; Enterovirus 71; Oral vaccine; Transgenic mice; VP1 capsid protein

Indexed keywords

PLACEBO; PROTEIN VP1;

ANIMAL CELL; ANTIBODY DETECTION; ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; ENTEROVIRUS 71; GENOTYPE; HUMAN; MILK; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRUS INFECTION; VIRUS NEUTRALIZATION; VIRUS STRAIN;

ADMINISTRATION, ORAL; AGING; ANIMALS; ANTIBODIES, VIRAL; CAPSID PROTEINS; CHILD, PRESCHOOL; DNA, COMPLEMENTARY; ENTEROVIRUS A, HUMAN; ENTEROVIRUS INFECTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENOTYPE; HUMANS; IMMUNOBLOTTING; LACTALBUMIN; MICE; MICE, INBRED ICR; MICE, TRANSGENIC; MILK; NEUTRALIZATION TESTS; PROMOTER REGIONS (GENETICS); VIRAL FUSION PROTEINS; VIRAL VACCINES;

EID: 43249110801     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2008.03.041     Document Type: Article

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