Human herpesvirus-6 infection: A prospective study evaluating HHV-6 DNA levels in liver from children with acute liver failure

Journal of Medical Virology

Volumn 80, Issue 6, 2008, Pages 1051-1057

  Chevret, Laurent ^a   Boutolleau, David ^a,b   Halimi Idri, Nadia ^a   Branchereau, Sophie ^a   Baujard, Catherine ^a   Fabre, Monique ^a   Gautheret Dejean, Agnès ^b   Debray, Dominique ^a  

^a BICÊTRE HOSPITAL   (France)

^b PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

Acute liver failure; Children; Diagnosis; Human herpesvirus 6; Real time PCR

Indexed keywords

VIRUS DNA;

ARTICLE; AUTOIMMUNE HEPATITIS; CHRONIC LIVER DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENOMICS; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; INFANT; LIVER FAILURE; LIVER TRANSPLANTATION; MALE; REAL TIME POLYMERASE CHAIN REACTION; VIRUS DETECTION; VIRUS LOAD;

CHILD; CHILD, PRESCHOOL; DNA, VIRAL; FEMALE; HERPESVIRUS 6, HUMAN; HUMANS; INFANT; LEUKOCYTES, MONONUCLEAR; LIVER; LIVER FAILURE, ACUTE; LIVER TRANSPLANTATION; MALE; PROSPECTIVE STUDIES; ROSEOLOVIRUS INFECTIONS;

HUMAN HERPESVIRUS 6;

EID: 43249101189     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21143     Document Type: Article

References (34)

1. Ablashi DV, Agut H, Berneman Z, Campadelli-Fiume G, Carrigan D, Ceccerini-Nelli L, Chandran B, Chou S, Collandre H, Cone R, Dambaugh T, Dewhurst S, DiLuca D, Foa-Tomasi L, Fleckenstein B, Frenkel N, Gallo R, Gompels U, Hall C, Jones M, Lawrence G, Martin M, Montagnier L, Neipel F, Nicholas J, Pellett P, Razzaque A, Torrelli G, Thomson B, Salahuddin S, Wyatt L, Yamanishi K. 1993. Human herpesvirus-6 strain groups: A nomenclature. Arch Virol 129:363-366.
2. Asano Y, Yoshikawa T, Suga S, Yazaki T, Kondo K, Yamanishi K. 1990. Fatal fulminant hepatitis in an infant with human herpesvirus-6 infection. Lancet 335:862-863.
3. Asano Y, Yoshikawa T, Kajita Y, Ogura R, Suga S, Yazaki T, Nakashima T, Yamada A, Kurata T. 1992. Fatal encephalitis/encephalopathy in primary human herpesvirus-6 infection. Arch Dis Child 67:1484-1485.
4. Asano Y, Yoshikawa T, Suga S, Kobayashi I, Nakashima T, Yazaki T, Kajita Y, Ozaki T. 1994. Clinical features of infants with primary human herpesvirus 6 infection (exanthem subitum, roseola infantum). Pediatrics 93:104-108.
5. Aubin JT, Collandre H, Candotti D, Ingrand D, Rouzioux C, Burgard M, Richard S, Huraux JM, Agut H. 1991. Several groups among human herpesvirus 6 strains can be distinguished by Southern blotting and polymerase chain reaction. J Clin Microbiol 29:367-372.
6. Aubin JT, Poirel L, Robert C, Huraux JM, Agut H. 1994. Identification of human herpesvirus 6 variants A and B by amplimer hybridization with variant-specific oligonucleotides and amplification with variant-specific primers. J Clin Microbiol 32:2434-2440.
7. Berneman ZN, Ablashi DV, Li G, Eger-Fletcher M, Reitz MS Jr, Hung CL, Brus I, Komaroff AL, Gallo RC. 1992. Human herpesvirus 7 is a T-lymphotropic virus and is related to, but significantly different from, human herpesvirus 6 and human cytomegalovirus. Proc Natl Acad Sci USA 89:10552-10556.
8. Boutolleau D, Fernandez C, Andre E, Imbert-Marcille BM, Milpied N, Agut H, Gautheret-Dejean A. 2003. Human herpesvirus (HHV)-6 and HHV-7: Two closely related viruses with different infection profiles in stem cell transplantation recipients. J Infect Dis 187:179-186.
9. Boutolleau D, Bonduelle O, Sabard A, Devers L, Agut H, Gautheret-Dejean A. 2005. Detection of human herpesvirus 7 DNA in peripheral blood reflects mainly CD4+ cell count in patients infected with HIV. J Med Virol 76:223-228.
10. Cacheux W, Carbonell N, Rosmorduc O, Wendum D, Paye F, Poupon R, Chazouilleres O, Gozlan J. 2005. HHV-6-related acute liver failure in two immunocompetent adults: Favourable outcome after liver transplantation and/or ganciclovir therapy. J Intern Med 258:573-578.
11. Cermelli C, Concari M, Carubbi F, Fabio G, Sabbatini AM, Pecorari M, Pietrosemoli P, Meacci M, Guicciardi E, Carulli N, Portolani M. 1996. Growth of human herpesvirus 6 in HEPG2 cells. Virus Res 45:75-85.
12. Challoner PB, Smith KT, Parker JD, MacLeod DL, Coulter SN, Rose TM, Schultz ER, Bennett JL, Garber RL, Chang M, et al. 1995. Plaque-associated expression of human herpesvirus 6 in multiple sclerosis. Proc Natl Acad Sci USA 92:7440-7444.
13. Dewhurst S, McIntyre K, Schnabel K, Hall CB. 1993. Human herpesvirus 6 (HHV-6) variant B accounts for the majority of symptomatic primary HHV-6 infections in a population of U.S. infants. J Clin Microbiol 31:416-418.
14. Di Luca D, Mirandola P, Ravaioli T, Bigoni B, Cassai E. 1996. Distribution of HHV-6 variants in human tissues. Infect Agents Dis 5:203-214.
15. Dockrell DH, Paya CV. 2001. Human herpesvirus-6 and -7 in transplantation. Rev Med Virol 11:23-36.
16. Drouet E, Michelson S, Denoyel G, Colimon R. 1993. Polymerase chain reaction detection of human cytomegalovirus in over 2000 blood specimens correlated with virus isolation and related to urinary virus excretion. J Virol Methods 45:259-276.
17. Durand P, Debray D, Mandel R, Baujard C, Branchereau S, Gauthier F, Jacquemin E, Devictor D. 2001. Acute liver failure in infancy: A 14-year experience of a pediatric liver transplantation center. J Pediatr 139:871-876.
18. Gautheret-Dejean A, Manichanh C, Thien-Ah-Koon F, Fillet AM, Mangeney N, Vidaud M, Dhedin N, Vernant JP, Agut H. 2002. Development of a real-time polymerase chain reaction assay for the diagnosis of human herpesvirus-6 infection and application to bone marrow transplant patients. J Virol Methods 100:27-35.
19. Hall CB, Long CE, Schnabel KC, Caserta MT, McIntyre KM, Costanzo MA, Knott A, Dewhurst S, Insel RA, Epstein LG. 1994. Human herpesvirus-6 infection in children. A prospective study of complications and reactivation. N Engl J Med 331:432-438.
20. Huang LM, Lee CY, Lin KH, Chuu WM, Lee PI, Chen RL, Chen JM, Lin DT. 1990. Human herpesvirus-6 associated with fatal haemophagocytic syndrome. Lancet 336:60-61.
21. Inagi R, Guntapong R, Nakao M, Ishino Y, Kawanishi K, Isegawa Y, Yamanishi K. 1996. Human herpesvirus 6 induces IL-8 gene expression in human hepatoma cell line, He p G2. J Med Virol 49:34-40.
22. Ishikawa K, Hasegawa K, Naritomi T, Kanai N, Ogawa M, Kato Y, Kobayashi M, Torii N, Hayashi N. 2002. Prevalence of herpesviridae and hepatitis virus sequences in the livers of patients with fulminant hepatitis of unknown etiology in Japan. J Gastroenterol 37:523-530.
23. Laurendeau I, Bahuau M, Vodovar N, Larramendy C, Olivi M, Bieche I, Vidaud M, Vidaud D. 1999. TaqMan PCR-based gene dosage assay for predictive testing in individuals from a cancer family with INK4 locus haploinsufficiency. Clin Chem 45:982-986.
24. Lautenschlager I, Linnavuori K, Hockerstedt K. 2000. Human herpesvirus-6 antigenemia after liver transplantation. Transplantation 69:2561-2566.
25. Lawrence GL, Chee M, Craxton MA, Gompels UA, Honess RW, Barrell BG. 1990. Human herpesvirus 6 is closely related to human cytomegalovirus. J Virol 64:287-299.
26. Mendel I, de Matteis M, Bertin C, Delaporte B, Maguer D, Collandre H, Buffet-Janvresse C. 1995. Fulminant hepatitis in neonates with human herpesvirus 6 infection. Pediatr Infect Dis J 14:993-997.
27. Okuno T, Takahashi K, Balachandra K, Shiraki K, Yamanishi K, Takahashi M, Baba K. 1989. Seroepidemiology of human herpesvirus 6 infection in normal children and adults. J Clin Microbiol 27:651-653.
28. Ozaki Y, Tajiri H, Tanaka-Taya K, Mushiake S, Kimoto A, Yamanishi K, Okada S. 2001. Frequent detection of the human herpesvirus 6-specific genomes in the livers of children with various liver diseases. J Clin Microbiol 39:2173-2177.
29. Prezioso PJ, Cangiarella J, Lee M, Nuovo GJ, Borkowsky W, Orlow SJ, Greco MA. 1992. Fatal disseminated infection with human herpesvirus-6. J Pediatr 120:921-923.
30. Salahuddin SZ, Ablashi DV, Markham PD, Josephs SF, Sturzenegger S, Kaplan M, Halligan G, Biberfeld P, Wong-Staal F, Kramarsky B., et al. 1986. Isolation of a new virus, HBLV, in patients with lymphoproliferative disorders. Science 234:596-601.
31. Schmitt K, Deutsch J, Tulzer G, Meindi R, Aberle S. 1996. Autoimmune hepatitis and adrenal insufficiency in an infant with human herpesvirus-6 infection. Lancet 348:966.
32. Sobue R, Miyazaki H, Okamoto M, Hirano M, Yoshikawa T, Suga S, Asano Y. 1991. Fulminant hepatitis in primary human herpesvirus-6 infection. N Engl J Med 324:1290.
33. Yamanishi K, Okuno T, Shiraki K, Takahashi M, Kondo T, Asano Y, Kurata T. 1988. Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet 1:1065-1067.
34. Zerr DM, Meier AS, Selke SS, Frenkel LM, Huang ML, Wald A, Rhoads MP, Nguy L, Bornemann R, Morrow RA, Corey L. 2005. A population-based study of primary human herpesvirus 6 infection. N Engl J Med 352:768-776.