Diagnosis of pancreaticobiliary malignancy by detection of minichromosome maintenance protein 5 in bile aspirates

British Journal of Cancer

Volumn 98, Issue 9, 2008, Pages 1548-1554

  Ayaru, L ^a   Stoeber, K ^a,b   Webster, G J ^c   Hatfield, A R W ^c   Wollenschlaeger, A ^a   Okoturo, O ^b   Rashid, M ^a   Williams, G ^a,b,d   Pereira, S P ^a,c,d  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

^c UNIVERSITY COLLEGE LONDON HOSPITALS   (United Kingdom)

^d ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

Author keywords

Biliary stricture; Biliary tract cancer; MCM; Pancreatic cancer

Indexed keywords

MINICHROMOSOME MAINTENANCE PROTEIN 2; MINICHROMOSOME MAINTENANCE PROTEIN 5;

ADULT; AGED; ARTICLE; ASPIRATION; AUTOMATION; BILE DUCT OBSTRUCTION; BILIARY TRACT CANCER; BRUSH BORDER; CANCER DIAGNOSIS; CONTROLLED STUDY; CYTOLOGY; DOWN REGULATION; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FEMALE; FLUOROMETRY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; PANCREAS CANCER; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SENSITIVITY ANALYSIS;

ADULT; AGED; BILE; BILIARY TRACT NEOPLASMS; CELL CYCLE PROTEINS; CHOLANGIOPANCREATOGRAPHY, ENDOSCOPIC RETROGRADE; DNA REPLICATION; FEMALE; FLUOROIMMUNOASSAY; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NUCLEAR PROTEINS; PANCREATIC NEOPLASMS; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 43249095653     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/sj.bjc.6604342     Document Type: Article

References (25)

1. Baron TH, Harewood GC, Rumalla A, Pochron NL, Stadheim LM, Gores GJ, Therneau TM, De Groen PC, Sebo TJ, Salomao DR, Kipp BR (2004) A prospective comparison of digital image analysis and routine cytology for the identification of malignancy in biliary tract strictures. Clin Gastroenterol Hepatol 2: 214-219
2. Blow JJ, Hodgson B (2002) Replication licensing - defining the proliferative state? Trends Cell Biol 12: 72-78
3. De Bellis M, Sherman S, Fogel EL, Cramer H, Chappo J, McHenry Jr L, Watkins JL, Lehman GA (2002a) Tissue sampling at ERCP in suspected malignant biliary strictures (Part 1). Gastrointest Endosc 56: 552-561
4. de Bellis M, Sherman S, Fogel EL, Cramer H, Chappo J, McHenry Jr L, Watkins JL, Lehman GA (2002b) Tissue sampling at ERCP in suspected malignant biliary strictures (Part 2). Gastrointest Endosc 56: 720-730
5. Freeman A, Morris LS, Mills AD, Stoeber K, Laskey RA, Williams GH, Coleman N (1999) Minichromosome maintenance proteins as biological markers of dysplasia and malignancy. Clin Cancer Res 5: 2121-2132
6. Fritscher-Ravens A, Broering DC, Knoefel WT, Rogiers X, Swain P, Thonke F, Bobrowski C, Topalidis T, Soehendra N (2004) EUS-guided fine-needle aspiration of suspected hilar cholangiocarcinoma in potentially operable patients with negative brush cytology. Am J Gastroenterol 99: 45-51
7. Gress TM (2004) Molecular diagnosis of pancreatobiliary malignancies in brush cytologies of biliary strictures. Gut 53: 1727-1729
8. Hamer OW, Feuerbach S (2006) How useful is integrated PET and CT for the management of pancreatic cancer? Nat Clin Pract Gastroenterol Hepatol 3: 74-75
9. Harewood GC, Baron TH, Stadheim LM, Kipp BR, Sebo TJ, Salomao DR (2004) Prospective, blinded assessment of factors influencing the accuracy of biliary cytology interpretation. Am J Gastroenterol 99: 1464-1469
10. Jailwala J, Fogel EL, Sherman S, Gottlieb K, Flueckiger J, Bucksot LG, Lehman GA (2000) Triple-tissue sampling at ERCP in malignant biliary obstruction. Gastrointest Endosc 51: 383-390
11. Kearsey SE, Labib K (1998) MCM proteins: evolution, properties, and role in DNA replication. Biochim Biophys Acta 1398: 113-136
12. Khan SA, Thomas HC, Davidson BR, Taylor-Robinson SD (2005) Cholangiocarcinoma. Lancet 366: 1303-1314
13. Lazaridis KN, Gores GJ (2005) Cholangiocarcinoma. Gastroenterology 128: 1655-1667
14. Lee JG (2006) Brush cytology and the diagnosis of pancreaticobiliary malignancy during ERCP. Gastrointest Endosc 63: 78-80
15. Mansfield JC, Griffin SM, Wadehra V, Matthewson K (1997) A prospective evaluation of cytology from biliary strictures. Gut 40: 671-677
16. Moreno Luna LE, Kipp B, Halling KC, Sebo TJ, Kremers WK, Roberts LR, Barr Fritcher EG, Levy MJ, Gores GJ (2006) Advanced cytologic techniques for the detection of malignant pancreatobiliary strictures. Gastroenterology 131: 1064-1072
17. Ponchon T, Gagnon P, Berger F, Labadie M, Liaras A, Chavaillon A, Bory R (1995) Value of endobiliary brush cytology and biopsies for the diagnosis of malignant bile duct stenosis: results of a prospective study. Gastrointest Endosc 42: 565-572
18. Stoeber K, Halsall I, Freeman A, Swinn R, Doble A, Morris L, Coleman N, Bullock N, Laskey RA, Hales CN, Williams GH (1999) Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine. Lancet 354: 1524-1525
19. Stoeber K, Mills AD, Kubota Y, Krude T, Romanowski P, Marheineke K, Laskey RA, Williams GH (1998) Cdc6 protein causes premature entry into S phase in a mammalian cell-free system. EMBO J 17: 7219-7229
20. Stoeber K, Swinn R, Prevost AT, de Clive-Lowe P, Halsall I, Dilworth SM, Marr J, Turner WH, Bullock N, Doble A, Hales CN, Williams GH (2002) Diagnosis of genito-urinary tract cancer by detection of minichromosome maintenance 5 protein in urine sediments. J Natl Cancer Inst 94: 1071-1079
21. Stoeber K, Tlsty TD, Happerfield L, Thomas GA, Romanov S, Bobrow L, Williams ED, Williams GH (2001) DNA replication licensing and human cell proliferation. J Cell Sci 114: 2027-2041
22. Wharton SB, Chan KK, Anderson JR, Stoeber K, Williams GH (2001) Replicative Mcm2 protein as a novel proliferation marker in oligodendrogliomas and its relationship to Ki67 labelling index, histological grade and prognosis. Neuropathol Appl Neurobiol 27: 305-313
23. Williams G, Stoeber K (1999) Clinical applications of a novel mammalian cell-free DNA replication system. Br J Cancer 80(Suppl 1): 20-24
24. Williams GH, Romanowski P, Morris L, Madine M, Mills AD, Stoeber K, Marr J, Laskey RA, Coleman N (1998) Improved cervical smear assessment using antibodies against proteins that regulate DNA replication. Proc Natl Acad Sci USA 95: 14932-14937
25. Williams GH, Swinn R, Prevost AT, De Clive-Lowe P, Halsall I, Going JJ, Hales CN, Stoeber K, Middleton SJ (2004) Diagnosis of oesophageal cancer by detection of minichromosome maintenance 5 protein in gastric aspirates. Br J Cancer 91: 714-719