Effects of aromatase inhibitor (Fadrozole)-induced sex-reversal on gonadal differentiation and mRNA expression of P450arom, AMH and ERα in embryos and growth in posthatching quail

Journal of Poultry Science

Volumn 45, Issue 2, 2008, Pages 116-124

  Koba, Naomi ^a   Mori, Masahiko ^a   Ha, Yonju ^a   Mizushima, Shusei ^a   Tsukada, Akira ^a   Saito, Noboru ^a   Ono, Tamao ^b   Shimada, Kiyoshi ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b SHINSHU UNIVERSITY   (Japan)

Author keywords

Aromatase inhibitor; P450arom mRNA; Quail gonad; Sex reversal

Indexed keywords

PHASIANIDAE;

EID: 43249093260     PISSN: 13467395     EISSN: 13490486     Source Type: Journal    
DOI: 10.2141/jpsa.45.116     Document Type: Article

References (38)

1. arom messenger ribonucleic acid of gonads in chicken embryos. General and Comparative Endocrinology, 102: 241-246. 1996.
2. arom) mRNA expression in adult chicken gonads. Japanese Poultry Science, 34: 158-168. 1997a.
3. arom mRNA of gonads in broiler embryos and broiler chickens. Japanese Poultry Science, 34: 318-328. 1997b.
4. Abinawanto, Zhang C, Saito N, Matsuda Y and Shimada K. Identification of sperm-bearing female-specific chromosome in the sex-reversed chicken. Journal of Experimental Zoology, 280: 65-72. 1998.
5. Akazome Y, Abe T and Mori T. Differentiation of chicken gonad as an endocrine organ: expression of LH receptor, FSH receptor, cytochrome P450c17 and aromatase genes. Reproduction, 123: 721-728. 2002.
6. Andrews JE, Smith CA and Sinclair AH. Sites of estrogen receptor and aromatase expression in the chicken embryo. General and Comparative Endocrinology, 108: 182-190. 1997.
7. Burke WH and Henry MH. Gonadal development and growth of chickens and turkeys hatched from eggs injected with an aromatase inhibitor. Poultry Science, 78: 1019-1033. 1999.
8. Chairun Nisa U, Tsukada A, Mori M, Saito N and Shimada K. Expression of protamine mRNA in relation to spermatogenic activity in Japanese quail. Journal of Poultry Science, 40: 309-318. 2003.
9. Elbrecht A and Smith RG. Aromatase enzyme activity and sex determination in chickens. Science, 255: 467-470. 1992.
10. Ellegren H. Hens, cocks and avian sex determination. EMBO Reports, 2: 192-196. 2001.
11. Etches RJ and Kagami H. Genotypic and phenotypic sex reversal. In: Perspectives in Avian Endocrinology (Harvey S and Etches RJ eds.). pp. 57-67. Journal of Endocrinology Ltd. Bristol. 1997.
12. Govoroun MS, Pannetier M, Pailhoux E, Cocquet J, Brillard JP, Couty I, Batellier F and Cotinot C. Isolation of chicken homolog of the FOXL2 gene and comparison of its expression patterns with those of aromatase during ovarian development. Developmental Dynamics, 231: 859-870. 2004.
13. 17-20 lyase, and P450 aromatase in fetal mouse gonads. Endocrinology, 135: 262-268. 1994.
14. Hirabayashi N, Matsuki Y, Suzuki E, Usami M, Ohno Y and Shimada K. Toxicokinetic study of Fadrozole, a nonsteroidal aromatase inhibitor, in chicken eggs by the injection into the air sac. Japanese Poultry Science, 36: 382-387. 1999.
15. Hrabia A, Takagi S and Shimada K. Variable response to hormonal induction of multiple ovulation in quail. Journal of Poultry Science, 40: 231-238. 2003.
16. Hudson QJ, Smith CA and Sinclair AH. Aromatase inhibition reduces expression of FOXL2 in the embryonic chicken ovary. Developmental Dynamics, 233: 1052-1055. 2005.
17. Kamata R, Takahashi S and Morita M. Gene expression of sex-determining factors and steroidogenic enzymes in the chicken embryo: influence of xenoestrogens. General and Comparative Endocrinology, 138: 148-156. 2004.
18. Lasala C, Carré-Eusèbe D, Picard J-Y and Rey R. Subcellular and molecular mechanisms regulating anti-Müllerian hormone gene expression in mammalian and nonmammalian species. DNA and Cell Biology, 23: 572-585. 2004.
19. Lin M, Thorne MH, Martin IC, Sheldon BL and Jones RC. Development of the gonads in the triploid (ZZW and ZZZ) fowl, Gallus domesticus, and comparison with normal diploid males (ZZ) and females (ZW). Reproduction, Fertility, and Development, 7: 1185-1197. 1995.
20. Mizuno S, Kunita R, Nakabayashi O, Kuroda Y, Arai N, Harata M, Ogawa A, Itoh Y, Teranishi M and Hori T. Z and W chromosomes of chickens: studies on their gene functions in sex determination and sex differentiation. Cytogenetic and Genome Research, 99: 236-244. 2002.
21. Nakabayashi O, Kikuchi H, Kikuchi T and Mizuno S. Differential expression of genes for aromatase and estrogen receptor during the gonadal development in chicken embryos. Journal of Molecular Endocrinology, 20: 193-202. 1998.
22. Nanda I, Shan Z, Schartl M, Burt DW, Koehler M, Nothwang H, Grützner F, Paton IR, Windsor D, Dunn I, Engel W, Staeheli P, Mizuno S, Haaf T and Schmid M. 300 million years of conserved synteny between chicken Z and human chromosome 9. Nature Genetics, 21: 258-259. 1999.
23. Nishikimi H, Kansaku N, Saito N, Usami M, Ohno Y and Shimada K. Sex differentiation and mRNA expression of P 450c17, P450arom and AMH in gonads of the chicken. Molecular Reproduction and Development, 55: 20-30. 2000.
24. Nomura O, Nakabayashi O, Nishimori K, Yasue H and Mizuno S. Expression of five steroidogenic genes including aromatase gene at early developmental stages of chicken male and female embryos. Journal of Steroid Biochemistry & Molecular Biology, 71: 103-109. 1999.
25. Oréal E, Mazaud S, Picard J-Y, Magre S, Carré-Eusèbe D. Different patterns of Anti- Müllerian hormone expression, as related to DMRT1, SF-1, WT1, GATA-4, Wnt-4 and Lhx9 expression, in the chick differentiating gonads. Developmental Dynamics, 225: 221-232. 2002.
26. Parma P, Pailhoux E and Cotinot C. Reverse transcription-polymerase chain reaction analysis of genes involved in gonadal differentiation in pigs. Biology of Reproduction, 61: 741-748. 1999.
27. Ro S and Kondo K. Inhibitory effect of exogenous estrogen on the testicular size of the embryo in the Japanese quail. Animal Science Journal, 48: 13-21. 1977a.
28. Ro S and Kondo K. Female like gonadal patterns of the male embryos of Japanese quail with a high dose of exogenous estrogen to early stage of incubation. Animal Science Journal, 48: 325-330. 1977b.
29. Shimada K. Gene expression of steroidogenic enzymes in chicken embryonic gonads. Journal of Experimental Zoology, 281: 450-456. 1998.
30. Smith CA, Andrews JE and Sinclair AH. Gonadal sex differentiation in chicken embryos: expression of estrogen receptor and aromatase genes. Journal of Steroid Biochemistry and Molecular Biology, 60: 295-302. 1997.
31. Smith CA, McClive PJ, Western PS, Reed KJ and Sinclair AH. Conservation of a sex-determining gene. Nature, 402: 601-602. 1999a.
32. Smith CA, Smith MJ and Sinclair AH. Gene expression during gonadogenesis in the chicken embryo. Gene, 234: 395-402. 1999b.
33. Takagi S, Ono T, Tsukada A, Atsumi Y, Mizushima S, Saito N and Shimada K. Fertilization and blastoderm development of quail oocytes after intracytoplasmic injection of chicken sperm bearing a W chromosome. Poultry Science, 86: 937-943. 2007a.
34. Takagi S, Ono T, Tsukada A, Atsumi Y, Mizushima S, Saito N and Shimada K. Z-Chromosome specific primers for chicken-quail hybrid blastoderm. Journal of Poultry Science, 44: 209-212. 2007b.
35. Takagi S, Tsukada A, Saito N and Shimada K. Fertilizing ability of chicken sperm bearing W chromosome. Poultry Science, 86: 731-738. 2007c.
36. Vaillant S, Dorizzi M, Pieau C and Richard-Mercier N. Sex reversal and aromatase in chicken. Journal of Experimental Zoology, 290: 727-740. 2001.
37. Yamamoto I, Tsukada A, Saito N and Shimada K. Profiles of mRNA expression of genes related to sex differentiation of the gonads in the chicken embryo. Poultry Science, 82: 1462-1467. 2003.
38. 17α hydroxylase and P450 aromatase genes in the chicken gonad before and after sexual differentiation. General and Comparative Endocrinology, 102: 233-240. 1996.