Sub one minute inhibition assays for the major cytochrome P450 enzymes utilizing ultra-performance liquid chromatography/tandem mass spectrometry

Rapid Communications in Mass Spectrometry

Volumn 22, Issue 9, 2008, Pages 1345-1350

  Rainville, Paul D ^a   Wheaton, Jessalynn P ^b   Alden, Peter G ^a   Plumb, Robert S ^a  

^a WATERS CORPORATION   (United States)

^b Davis Companies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASSAYS; DRUG PRODUCTS; ENZYME INHIBITION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; SUBSTRATES;

2 MICRON; CYTOCHROME P450 ENZYMES; CYTOCHROMES P450; DRUG DISCOVERY; INHIBITION ASSAYS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY/TANDEM MASS SPECTROMETRY; MEASUREMENTS OF; NEW CHEMICAL ENTITIES; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

PROBES;

EID: 43249092372     PISSN: 09514198     EISSN: 10970231     Source Type: Journal    
DOI: 10.1002/rcm.3465     Document Type: Article

References (13)