The effect of binge fetal alcohol exposure on the number of vasoactive intestinal peptide-producing neurons in fetal sheep brain

Developmental Neuroscience

Volumn 30, Issue 4, 2008, Pages 276-284

  Anderson, David J ^a   Mondares, Robin L ^a   Born, Donald E ^a   Gleason, Christine A ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Cerebral vasodilation; Fetal alcohol exposure; Neurons; Unbiased stereology; Vasoactive intestinal peptide

Indexed keywords

ALCOHOL; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; CELL COUNT; CELL MATURATION; CELL POPULATION; CONTROLLED STUDY; EXPOSURE; FETUS; HEMISPHERE; IMMUNOHISTOCHEMISTRY; NERVE CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHEEP; STEREOLOGY;

ANIMALS; CELL COUNT; FEMALE; FETAL ALCOHOL SYNDROME; GESTATIONAL AGE; HYPOXIA, BRAIN; IMMUNOHISTOCHEMISTRY; MALE; NEURONS; PREGNANCY; PROSENCEPHALON; SHEEP; VASOACTIVE INTESTINAL PEPTIDE;

EID: 43249087589     PISSN: 03785866     EISSN: None     Source Type: Journal    
DOI: 10.1159/000110349     Document Type: Article

References (49)

1. Abel EL, Sokol RJ (1986): Fetal alcohol syndrome is now leading cause of mental retardation. Lancet 2:1222.
2. American Academy of Pediatrics, Committee on Substance Abuse and Committee on Children with Disabilities (2000): Fetal alcohol syndrome and alcohol-related neurodevelopmental disorders. Pediatrics 106:358-361.
3. Antonopoulos J, Papadopoulos GC, Karamanlidis AN, Parnavelas JG, Dinopoulos A, Michaloudi H (1987): VIP- and CCK-like-immunoreactive neurons in the hedgehog (Erinaceus europaeus) and sheep (Ovis aries) brain. J Comp Neurol 263:290-307.
4. Bailey CD, Brien JF, Reynolds JN (2004): Chronic prenatal ethanol exposure alters the proportion of GABAergic neurons in layers II/III of the adult guinea pig somatosensory cortex. Neurotoxicol Teratol 26:59-63.
5. Bayraktar T, Welker E, Freund TF, Zilles K, Staiger JF (2000): Neurons immunoreactive for vasoactive intestinal polypeptide in the rat primary somatosensory cortex: morphology and spatial relationship to barrel-related columns. J Comp Neurol 420:291-304.
6. Benagiano V, Virgintino D, Maiorano E, Rizzi A, Palombo S, Roncali L, Ambrosi G (1996): VIP-like immunoreactivity within neurons and perivascular neuronal processes of the human cerebral cortex. Eur J Histochem 40:53-56.
7. Brenneman DE, Gozes I (1996): A femtomolar-acting neuroprotective peptide. J Clin Invest 97:2299-2307.
8. Brenneman DE, Spong CY, Gozes I (2000): Protective peptides derived from novel glial proteins. Biochem Soc Trans 28:452-455.
9. Caetano R, Ramisetty-Mikler S, Floyd LR, Mc-Grath C (2006): The epidemiology of drinking among women of child-bearing age. Alcohol Clin Exp Res 30:1023-1030.
10. Cameron HA, Hazel TG, McKay RD (1998): Regulation of neurogenesis by growth factors and neurotransmitters. J Neurobiol 36:287-306.
11. Cattoretti G, Pileri S, Parravicini C, Becker MH, Poggi S, Bifulco C, Key G, D'Amato L, Sabattini E, Feudale E, Reynolds F, Gerdes J, Rilke F (1993): Antigen unmasking on formalin-fixed, paraffin-embedded tissue sections. J Pathol 171:83-98.
12. Cauli B, Tong XK, Rancillac A, Serluca N, Lambolez B, Rossier J, Hamel E (2004): Cortical GABA interneurons in neurovascular coupling: relays for subcortical vasoactive pathways. J Neurosci 24:8940-8949.
13. Chambers CD, Kavteladze L, Joutchenko L, Bakhireva LN, Jones KL (2006): Alcohol consumption patterns among pregnant women in the Moscow region of the Russian Federation. Alcohol 38:133-137.
14. Chedotal A, Umbriaco D, Descarries L, Hartman BK, Hamel E (1994): Light and electron microscopic immunocytochemical analysis of the neurovascular relationships of choline acetyltransferase and vasoactive intestinal polypeptide nerve terminals in the rat cerebral cortex. J Comp Neurol 343:57-71.
15. Cohen G, Gressens P, Gallego J, Gaultier C (2002): Depression of hypoxic arousal response in adolescent mice following antenatal vasoactive intestinal polypeptide blockade. J Physiol 540:691-699.
16. Cudd TA, Chen WJ, Parnell SE, West JR (2001): Third trimester binge ethanol exposure results in fetal hypercapnea and acidemia but not hypoxemia in pregnant sheep. Alcohol Clin Exp Res 25:269-276.
17. Dejda A, Sokolowska P, Nowak JZ (2005): Neuroprotective potential of three neuropeptides PACAP, VIP and PHI. Pharmacol Rep 57:307-320.
18. Endres M, Toso L, Roberson R, Park J, Abebe D, Poggi S, Spong CY (2005): Prevention of alcohol-induced developmental delays and learning abnormalities in a model of fetal alcohol syndrome. Am J Obstet Gynecol 193:1028-1034.
19. Fahrenkrug J, Hannibal J, Tams J, Georg B (2000): Immunohistochemical localization of the VIP1 receptor (VPAC1R) in rat cerebral blood vessels: relation to PACAP and VIP containing nerves. J Cereb Blood Flow Metab 20:1205-1214.
20. Gladstone J, Levy M, Nulman I, Koren G (1997): Characteristics of pregnant women who engage in binge alcohol consumption. CMAJ 156:789-794.
21. Gleason CA, Iida H, Hotchkiss KJ, Northington FJ, Traystman RJ (1997): Newborn cerebrovascular responses after first trimester moderate maternal ethanol exposure in sheep. Pediatr Res 42:39-45.
22. Gozes I, Divinsky I, Pilzer I, Fridkin M, Brenneman DE, Spier AD (2003): From vasoactive intestinal peptide (VIP) through activity-dependent neuroprotective protein (ADNP) to NAP: a view of neuroprotection and cell division. J Mol Neurosci 20:315-322.
23. Gressens P, Besse L, Robberecht P, Gozes I, Fridkin M, Evrard P (1999): Neuroprotection of the developing brain by systemic administration of vasoactive intestinal peptide derivatives. J Pharmacol Exp Ther 288:1207-1213.
24. Gressens P, Hill JM, Gozes I, Fridkin M, Brenneman DE (1993): Growth factor function of vasoactive intestinal peptide in whole cultured mouse embryos. Nature 362:155-158.
25. Gressens P, Hill JM, Paindaveine B, Gozes I, Fridkin M, Brenneman DE (1994): Severe microcephaly induced by blockade of vasoactive intestinal peptide function in the primitive neuroepithelium of the mouse. J Clin Invest 94:2020-2027.
26. Gressens P, Marret S, Hill JM, Brenneman DE, Gozes I, Fridkin M, Evrard P (1997): Vasoactive intestinal peptide prevents excitotoxic cell death in the murine developing brain. J Clin Invest 100:390-397.
27. Halmesmaki E, Raivio KO, Ylikorkala O (1987): Patterns of alcohol consumption during pregnancy. Obstet Gynecol 69:594-597.
28. Hamel E (2004): Cholinergic modulation of the cortical microvascular bed. Prog Brain Res 145:171-178.
29. Heistad DD, Marcus ML, Said SI, Gross PM (1980): Effect of acetylcholine and vasoactive intestinal peptide on cerebral blood flow. Am J Physiol 239:H73-H80.
30. Itakura T, Yokote H, Okuno T, Naka Y, Nakakita K, Kamei I, Nakai K, Imai H, Komai N (1987): Regulation of rCBF by intracortical vasoactive intestinal polypeptide-containing neurons: immunohistochemical and hydrogen clearance study in rats. J Neurosurg 67:93-96.
31. Madeira MD, Andrade JP, Lieberman AR, Sousa N, Almeida OF, Paula-Barbosa MM (1997): Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels. J Neurosci 17:1302-1319.
32. Magistretti PJ (1990): VIP neurons in the cerebral cortex. Trends Pharmacol Sci 11:250-254.
33. Mayock DE, Ness D, Mondares RL, Gleason CA (2007): Binge alcohol exposure in the second trimester attenuates fetal cerebral blood flow response to hypoxia. J Appl Physiol 102:972-977.
34. Morrison JH, Magistretti PJ, Benoit R, Bloom FE (1984): The distribution and morphological characteristics of the intracortical VIP-positive cell: an immunohistochemical analysis. Brain Res 292:269-282.
35. Mwamengele GL, Mayhew TM, Dantzer V (1993): Purkinje cell complements in mammalian cerebella and the biases incurred by counting nucleoli. J Anat 183:155-160.
36. Paspalas CD, Papadopoulos GC (1998): Ultrastructural evidence for combined action of noradrenaline and vasoactive intestinal polypeptide upon neurons, astrocytes, and blood vessels of the rat cerebral cortex. Brain Res Bull 45:247-259.
37. Pozo D, Delgado M, Martinez M, Guerrero JM, Leceta J, Gomariz RP, Calvo JR (2000): Immunobiology of vasoactive intestinal peptide (VIP). Immunol Today 21:7-11.
38. Rojas JC, Vigueras RM, Sicilia G, Reyes G, Cintra L, Aguilar-Roblero R (1998): Effects of acute prenatal ethanol exposure on immunoreactive vasopressin and vasoactive intestinal polypeptide cells in the suprachiasmatic nucleus of the rat. Proc West Pharmacol Soc 41:55-56.
39. Sari Y, Gozes I (2006): Brain deficits associated with fetal alcohol exposure may be protected, in part, by peptides derived from activity-dependent neurotrophic factor and activity-dependent neuroprotective protein. Brain Res Rev 52:107-118.
40. Spong CY, Abebe DT, Gozes I, Brenneman DE, Hill JM (2001): Prevention of fetal demise and growth restriction in a mouse model of fetal alcohol syndrome. J Pharmacol Exp Ther 297:774-779.
41. Spong CY, Auth J, Vink J, Goodwin K, Abebe DT, Hill JM, Brenneman DE (2002): Vasoactive intestinal peptide mRNA and immunoreactivity are decreased in fetal alcohol syndrome model. Regul Pept 108:143-147.
42. Warren KR, Bast RJ (1988): Alcohol-related birth defects: an update. Public Health Rep 103:638-642.
43. Watari H, Born DE, Gleason CA (2006): Effects of first trimester binge alcohol exposure on developing white matter in fetal sheep. Pediatr Res 59:560-564.
44. West JR, Chen WJ, Pantazis NJ (1994): Fetal alcohol syndrome: the vulnerability of the developing brain and possible mechanisms of damage. Metab Brain Dis 9:291-322.
45. West JR, Parnell SE, Chen WJ, Cudd TA (2001): Alcohol-mediated Purkinje cell loss in the absence of hypoxemia during the third trimester in an ovine model system. Alcohol Clin Exp Res 25:1051-1057.
46. West MJ (2002): Design-based stereological methods for counting neurons. Prog Brain Res 135:43-51.
47. West MJ, Gundersen HJ (1990): Unbiased stereological estimation of the number of neurons in the human hippocampus. J Comp Neurol 296:1-22.
48. West MJ, Slomianka L, Gundersen HJ (1991): Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anat Rec 231:482-497.
49. Zhou JN, Hofman MA, Swaab DF (1996): Morphometric analysis of vasopressin and vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus: influence of microwave treatment. Brain Res 742:334-338.