Gender comparison of contractile performance and beta-adrenergic response in isolated rat cardiac trabeculae

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology

Volumn 178, Issue 3, 2008, Pages 307-313

  Monasky, Michelle M ^a   Varian, Kenneth D ^a   Janssen, Paul M L ^a  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

Adrenergic stimulation; Contractility; Gender; Intact myocardium; Relaxation

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE;

ANIMAL; ARTICLE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG EFFECT; ELECTROSTIMULATION; FEMALE; HEART CONTRACTION; HEART VENTRICLE; MALE; PHYSIOLOGY; RAT; RAT STRAIN; SEXUAL DEVELOPMENT;

ADRENERGIC BETA-AGONISTS; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; FEMALE; HEART VENTRICLES; ISOPROTERENOL; MALE; MYOCARDIAL CONTRACTION; RATS; RATS, INBRED STRAINS; RECEPTORS, ADRENERGIC, BETA; SEX CHARACTERISTICS;

RATTUS;

EID: 43149123779     PISSN: 01741578     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00360-007-0223-y     Document Type: Article

References (25)

1. Bairey Merz CN, Shaw LJ, Reis SE, Bittner V, Kelsey SF, Olson M, Johnson BD, Pepine CJ, Mankad S, Sharaf BL, Rogers WJ, Pohost GM, Lerman A, Quyyumi AA, Sopko G (2006) Insights from the NHLBI-sponsored women's ischemia syndrome evaluation (WISE) study: part II: gender differences in presentation, diagnosis, and outcome with regard to gender-based pathophysiology of atherosclerosis and macrovascular and microvascular coronary disease. J Am Coll Cardiol 47:S21-S29
2. Beyer ME, Yu G, Hanke H, Hoffmeister HM (2001) Acute gender-specific hemodynamic and inotropic effects of 17beta-estradiol on rats. Hypertension 38:1003-1010
3. Biondi-Zoccai GG, Baldi A, Biasucci LM, Abbate A (2004) Female gender, myocardial remodeling and cardiac failure: are women protected from increased myocardiocyte apoptosis? Ital Heart J 5:498-504
4. Brown NM, Setchell KD (2001) Animal models impacted by phytoestrogens in commercial chow: implications for pathways influenced by hormones. Lab Invest 81:735-747
5. Capasso JM, Remily RM, Smith RH, Sonnenblick EH (1983) Sex differences in myocardial contractility in the rat. Basic Res Cardiol 78:156-171
6. Chu SH, Sutherland K, Beck J, Kowalski J, Goldspink P, Schwertz D (2005) Sex differences in expression of calcium-handling proteins and beta-adrenergic receptors in rat heart ventricle. Life Sci 76:2735-2749
7. Das DK (2004) Sexual dimorphism and in the aging heart: role of estrogen, nitric oxide and beyond. J Mol Cell Cardiol 37:667-669
8. Deswal A, Bozkurt B (2006) Comparison of morbidity in women versus men with heart failure and preserved ejection fraction. Am J Cardiol 97:1228-1231
9. Fetters JK, Peterson ED, Shaw LJ, Newby LK, Califf RM (1996) Sex-specific differences in coronary artery disease risk factors, evaluation, and treatment: have they been adequately evaluated? Am Heart J 131:796-813
10. Hiranandani N, Varian KD, Monasky MM, Janssen PM (2006) Frequency-dependent contractile response of isolated cardiac trabeculae under hypo-, normo-, and hyperthermic conditions. J Appl Physiol 100:1727-1732
11. Jacobs AK (2006) Women, ischemic heart disease, revascularization, and the gender gap: what are we missing? J Am Coll Cardiol 47:S63-S65
12. Janssen PML, Hunter WC (1995) Force, not sarcomere length, correlates with prolongation of isosarcometric contraction. Am J Physiol Heart Circ Physiol 269:H676-H685
13. Janssen PML, Stull LB, Marban E (2002) Myofilament properties comprise the rate-limiting step for cardiac relaxation at body temperature in the rat. Am J Physiol Heart Circ Physiol 282:H499-H507
14. Layland J, Kentish JC (1999) Positive force- and [Ca2+]i-frequency relationships in rat ventricular trabeculae at physiological frequencies. Am J Physiol Heart Circ Physiol 276:H9-H18
15. Layland J, Kentish JC (2000) Effects of 1- or -adrenoceptor stimulation on work-loop and isometric contractions of isolated rat cardiac trabeculae. J Physiol (Lond) 524:205-219
16. Mulieri LA, Hasenfuss G, Ittleman F, Blanchard EM, Alpert NR (1989) Protection of human left ventricular myocardium from cutting injury with 2,3-butanedione monoxime. Circ Res 65:1441-1449
17. Patterson E, Ma L, Szabo B, Robinson CP, Thadani U (1998) Ovariectomy and estrogen-induced alterations in myocardial contractility in female rabbits: role of the L-type calcium channel. J Pharmacol Exp Ther 284:586-591
18. Raman S, Kelley MA, Janssen PM (2006) Effect of muscle dimensions on trabecular contractile performance under physiological conditions. Pflugers Arch 451:625-630
19. Regitz-Zagrosek V, Lehmkuhl E, Weickert MO (2006) Gender differences in the metabolic syndrome and their role for cardiovascular disease. Clin Res Cardiol 95:136-147
20. Schouten VJ, ter Keurs HE (1986) The force-frequency relationship in rat myocardium. The influence of muscle dimensions. Pflugers Arch 407:14-17
21. Shaw LJ, Bairey Merz CN, Pepine CJ, Reis SE, Bittner V, Kelsey SF, Olson M, Johnson BD, Mankad S, Sharaf BL, Rogers WJ, Wessel TR, Arant CB, Pohost GM, Lerman A, Quyyumi AA, Sopko G (2006) Insights from the NHLBI-sponsored women's ischemia syndrome evaluation (WISE) study: part I: gender differences in traditional and novel risk factors, symptom evaluation, and gender-optimized diagnostic strategies. J Am Coll Cardiol 47:S4-S20
22. Stull LB, Leppo M, Marban E, Janssen PML (2002) Physiological determinants of contractile force generation and calcium handling in mouse myocardium. J Mol Cell Cardiol 34:1367-1376
23. ter Keurs HE, Rijnsburger WH, van Heuningen R, Nagelsmit MJ (1980) Tension development and sarcomere length in rat cardiac trabeculae. Evidence of length-dependent activation. Circ Res 46:703-714
24. Vizgirda VM, Wahler GM, Sondgeroth KL, Ziolo MT, Schwertz DW (2002) Mechanisms of sex differences in rat cardiac myocyte response to beta-adrenergic stimulation. Am J Physiol Heart Circ Physiol 282:H256-H263
25. Vuolteenaho O, Ruskoaho H (2003) Gender matters: estrogen protects from cardiac hypertrophy. Trends Endocrinol Metab 14:52-54