Exhaled nitric oxide levels during treatment in patients hospitalized with asthma

Allergy and Asthma Proceedings

Volumn 29, Issue 2, 2008, Pages 171-176

  Baptist, Alan P ^a,b   Shah, Bhavish ^a   Wang, Yun ^a   Ager, Joel ^a   Safwan Badr, M ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE   (United States)

Author keywords

Asthma; Asthma exacerbation; Breath tests; Corticosteroids; Hospitalization; Nitric oxide; Relapse; Respiratory function tests; Spirometry; Treatment outcome

Indexed keywords

ANTIASTHMATIC AGENT; BIOLOGICAL MARKER; NITRIC OXIDE;

ADULT; ARTICLE; ASTHMA; CLINICAL TRIAL; EXHALATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMAN; IMMUNOLOGY; MALE; METABOLISM; MIDDLE AGED;

ADULT; ANTI-ASTHMATIC AGENTS; ASTHMA; BIOLOGICAL MARKERS; EXHALATION; FEMALE; FORCED EXPIRATORY VOLUME; HUMANS; MALE; MIDDLE AGED; NITRIC OXIDE;

EID: 43149100809     PISSN: 10885412     EISSN: None     Source Type: Journal    
DOI: 10.2500/aap.2008.29.3098     Document Type: Article

References (34)

1. Pleis JR, and Lethbridge-Cejku M. Summary health statistics for U.S. adults: National Health Interview Survey, 2005. Vital Health Stat 10 232:1-153, 2006.
2. Asthma prevalence and control characteristics by race/ethnicity - United States, 2002. MMWR Morb Mortal Wkly Rep 53: 145-148, 2004.
3. Singleton RJ, Holman RC, Cobb N, et al. Asthma hospitalizations among American Indian and Alaska Native people and for the general US population. Chest 130:1554-1562, 2006.
4. Kozak LJ, Owings MF, and Hall MJ. National Hospital Discharge Survey: 2002 Annual summary with detailed diagnosis and procedure data. Vital Health Stat 13 158:1-199, 2005.
5. Karras DJ, Sammon ME, Terregino CA, et al. Clinically meaningful changes in quantitative measures of asthma severity. Acad Emerg Med 7:327-334, 2000.
6. Kelly AM, Kerr D, and Powell C. Is severity assessment after one hour of treatment better for predicting the need for admission in acute asthma? Respir Med 98:777-781, 2004.
7. McCarren M, Zalenski RJ, McDermott M, and Kaur K. Predicting recovery from acute asthma in an emergency diagnostic and treatment unit. Acad Emerg Med 7:28-35, 2000.
8. Weber EJ, Silverman RA, Callaham ML, et al. A prospective multicenter study of factors associated with hospital admission among adults with acute asthma. Am J Med 113:371-378, 2002.
9. Manser R, Reid D, and Abramson M. Corticosteroids for acute severe asthma in hospitalised patients. Cochrane Database Syst Rev 1:CD001740, 2001.
10. National Institutes of Health (NIH). National Asthma Education and Prevention Program Expert Panel Report 2: Guidelines for the diagnosis and management of asthma. NIH Publication No. 97-4051, 1997.
11. Markoff BA, MacMillan JF Jr, and Kumra V. Discharge of the asthmatic patient. Clin Rev Allergy Immunol 20:341-355, 2001.
12. Belvisi MG, Stretton CD, Yacoub M, and Barnes PJ. Nitric oxide is the endogenous neurotransmitter of bronchodilator nerves in humans. Eur J Pharmacol 210:221-222, 1992.
13. Blitzer ML, Loh E, Roddy MA, et al. Endothelium-derived nitric oxide regulates systemic and pulmonary vascular resistance during acute hypoxia in humans. J Am Coll Cardiol 28:591-596, 1996.
14. Nathan C, and Xie QW. Nitric oxide synthases: Roles, tolls, and controls. Cell 78:915-918, 1994.
15. ATS/ERS recommendations for standardized procedures for the online and offline measurement of exhaled lower respiratory nitric oxide and nasal nitric oxide, 2005. Am J Respir Crit Care Med 171:912-930, 2005.
16. Massaro AF, Gaston B, Kita D, et al. Expired nitric oxide levels during treatment of acute asthma. Am J Respir Crit Care Med 152:800-803, 1995.
17. Strunk RC, Szefler SJ, Phillips BR, et al. Relationship of exhaled nitric oxide to clinical and inflammatory markers of persistent asthma in children. J Allergy Clin Immunol 112:883-892, 2003.
18. Baraldi E, Azzolin NM, Zanconato S, et al. Corticosteroids decrease exhaled nitric oxide in children with acute asthma. J Pediatr 131:381-385, 1997.
19. Baraldi E, Dario C, Ongaro R, et al. Exhaled nitric oxide concentrations during treatment of wheezing exacerbation in infants and young children. Am J Respir Crit Care Med 159:1284-1288, 1999.
20. Tsai YG, Lee MY, Yang KD, et al. A single dose of nebulized budesonide decreases exhaled nitric oxide in children with acute asthma. J Pediatr 139:433-437, 2001.
21. Kendrick KR, Baxi SC, and Smith RM. Usefulness of the modified 0-10 Borg scale in assessing the degree of dyspnea in patients with COPD and asthma. J Emerg Nurs 26:216-222, 2000.
22. Miller MR, Hankinson J, Brusasco V, et al. Standardisation of spirometry. Eur Respir J 26:319-338, 2005.
23. de Gouw HW, Hendriks J, Woltman AM, et al. Exhaled nitric oxide (NO) is reduced shortly after bronchoconstriction to direct and indirect stimuli in asthma. Am J Respir Crit Care Med 158(1):315-319, 1998.
24. Garcia-Rio F, Ramirez M, Mediano O, et al. Exhaled nitric oxide and airway caliber during exercise-induced bronchoconstriction. Int J Sports Med 27:905-910, 2006.
25. Bruce CT, Zhao D, Yates DH, and Thomas PS. AMP challenge induces a decrease in FE(NO) in asthmatic subjects modulated by nedocromil. Eur J Clin Invest 36:899-905, 2006.
26. Boot JD, Tarasevych S, Sterk PJ, et al. Reversal of the late asthmatic response increases exhaled nitric oxide. Respir Med 99:1591-1594, 2005.
27. Ho LP, Wood FT, Robson A, et al. The current single exhalation method of measuring exhales nitric oxide is affected by airway calibre. Eur Respir J 15:1009-1013, 2000.
28. Kraft M, Djukanovic R, Wilson S, et al. Alveolar tissue inflammation in asthma. Am J Respir Crit Care Med 154:1505-1510, 1996.
29. Lehtimaki L, Kankaanranta H, Saarelainen S, et al. Peripheral inflammation in patients with asthmatic symptoms but normal lung function. J Asthma 42:605-609, 2005.
30. Tsoukias NM, and George SC. A two-compartment model of pulmonary nitric oxide exchange dynamics. J Appl Physiol 85:653-666, 1998.
31. Berry M, Hargadon B, Morgan A, et al. Alveolar nitric oxide in adults with asthma: Evidence of distal lung inflammation in refractory asthma. Eur Respir J 25:986-991, 2005.
32. Gelb AF, Taylor CF, Nussbaum E, et al. Alveolar and airway sites of nitric oxide inflammation in treated asthma. Am J Respir Crit Care Med 170:737-741, 2004.
33. Dinakar C, Van Osdol TJ, Barnes CS, et al. Changes in exhaled nitric oxide levels with immunotherapy. Allergy Asthma Proc 27:140-144, 2006.
34. Gelb AF, Flynn Taylor C, Shinar CM, et al. Role of spirometry and exhaled nitric oxide to predict exacerbations in treated asthmatics. Chest 129:1492-1499, 2006.