Radiolabeling of a high potency cannabinoid subtype-1 receptor ligand, N-(4-fluoro-benzyl)-4-(3-(piperidin-1-yl)-indole-1-sulfonyl) benzamide (PipISB), with carbon-11 or fluorine-18

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 51, Issue 3, 2008, Pages 146-152

  Donohue, Sean R ^a,b   Halldin, Christer ^b   Schou, Magnus ^b   Hong, Jinsoo ^a   Phebus, Lee ^c   Chernet, Eyassu ^c   Hitchcock, Stephen A ^a,d   Gardinier, Kevin M ^c   Ruley, Kevin M ^c   Krushinski, Joseph H ^c   Schaus, John ^c   Pike, Victor W ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b KAROLINSKA INSTITUTE   (Sweden)

^c ELI LILLY AND COMPANY   (United States)

^d AMGEN INC   (United States)

Author keywords

Arylsulfonyl substituted indole; Carbon 11; CB1; Fluorine 18; PET; PipISB; Receptor

Indexed keywords

AMIDES; CARBON DIOXIDE; CYCLOTRONS; ELECTRONS; FLUORINE; FLUORINE COMPOUNDS; LIGANDS; POLYCYCLIC AROMATIC HYDROCARBONS; POSITRON EMISSION TOMOGRAPHY; POSITRONS;

ARYLSULFONYL-SUBSTITUTED INDOLE; BENZAMIDES; CARBON-11; FLUORINE-18; HIGH POTENCY; PIPISB; RADIOLABELLING; RECEPTOR; RECEPTOR LIGANDS; SUBSTITUTED INDOLES;

CARBON MONOXIDE;

CANNABINOID 1 RECEPTOR; CARBON 11; CARBON DIOXIDE; CARBON MONOXIDE; FLUORIDE ION; FLUORINE 18; FLUORINE DERIVATIVE; FLUOROBENZYL BROMIDE; N (4 FLUOROBENZYL) 4 [3 (PIPERIDIN 1 YL)INDOLE 1 SULFONYL]BENZAMIDE C 11; N (4 FLUOROBENZYL) 4 [3 (PIPERIDIN 1 YL)INDOLE 1 SULFONYL]BENZAMIDE F 18; RADIOLIGAND;

ANIMAL CELL; ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INSECT CELL CULTURE; ISOTOPE LABELING; NONHUMAN; RADIOCHEMISTRY; REACTION ANALYSIS;

EID: 43149098070     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1491     Document Type: Article

References (33)