Ischemia-reperfusion injury of rabbit ovary and protective effect of trapidil: An experimental study

Pediatric Surgery International

Volumn 24, Issue 3, 2008, Pages 315-318

  Somuncu, Salih ^a   Cakmak, Murat ^a   Dikmen, Gunnur ^b   Akman, Hülya ^a   Kaya, Murat ^a  

^a KIRIKKALE UNIVERSITY   (Turkey)

^b HACETTEPE UNIVERSITY   (Turkey)

Author keywords

Free oxygen radicals; Ischemia reperfusion injury; Ovarian torsion detorsion; Trapidil

Indexed keywords

3,4 METHYLENEDIOXYAMPHETAMINE; CATALASE; GLUTATHIONE PEROXIDASE; MALONALDEHYDE; ROCARNAL; SUPEROXIDE DISMUTASE; TRAPIDIL;

ADNEXA DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CONTROL GROUP; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; EXPERIMENTAL STUDY; FEMALE; ISCHEMIA; NONHUMAN; OVARIECTOMY; OVARY; OVARY TORSION; OXIDATIVE STRESS; PRIORITY JOURNAL; RABBIT; REPERFUSION INJURY; SHAM PROCEDURE; SINGLE DRUG DOSE; STATISTICAL SIGNIFICANCE; TORSION;

ANIMALS; CATALASE; FEMALE; GLUTATHIONE PEROXIDASE; LIPID PEROXIDATION; MALONDIALDEHYDE; OVARY; RABBITS; REPERFUSION INJURY; SUPEROXIDE DISMUTASE; TORSION ABNORMALITY; TRAPIDIL; VASODILATOR AGENTS;

EID: 43149092889     PISSN: 01790358     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00383-007-2079-3     Document Type: Article

References (19)

1. Hibbard L (1985) Adnexal torsion. Am J Obstet Gynecol 152:456-461
2. Bayer AI, Wiskand AK (1994) Adnexal torsion; can the adnexa be saved? Am J Obstet Gynecol 171:1506-1510
3. Bulkley GB (1987) Free radical mediated reperfusion injury: a selective review. Br J Cancer 55:66-69
4. Celik O, Turkoz Y, Hascelik S, Hascelik M, Cigrem Y, Mizrak B, Yologlu S (2004) The protective effect of caffeic acid phenetyl ester on ischemia-reperfusion injury in rat ovary. Eur J Obstet Gynecol and Reprod Biol 117:183-185
5. Turkoz Y, Celik O, Hascalik S, Cigremis Y, Hascelik M, Mizrak B, Yologlu S (2004) Melatonin reduces torsion-detorsion injury in rat ovary: biochemical and histopathologic evaluation. J Pineal Res 37:137-141
6. Sagsoz N, Kisa U, Apan A (2002) Ischemia-reperfusion injury of rat ovary and the effects of vitamin C, mannitol and verapamil. Hum Reprod 17:2972-2976
7. Block HU, Dunemann A, Niebrisch M, Mest HJ (1988) Influence of the antianginal drug trapidil and its derivate AR 12463 on arachidionic acid liberation and thromboxane formation in thrombine stimulated platelets. Biomed Biochem Acta 47:141-144
8. Heinroth-Hoffman I, Hauser A, Mest HJ (1987) Inhibition of thromboxane A2, production by trapidil and trapidil derivatives in the arachidonic acid injected rat. Prostaglandins Leukot Med 30:87-92
9. 2 synthesis in human umblical veins perused in vitro. Prostoglandins 49:311-318
10. Zhon L, Ismaili J, Stordeur P, Thielemans K, Goldman M, Pradier O (1999) Inhibition of the CD40 pathway of monocyte activation by triazolopyrimidine. Clin Immunol 93:232-238
11. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ (1951) Protein measurement with the Folin phenol reagent. J Clin Chem 193:265-269
12. Aebi H (1984) Catalase in vitro. Methods Enzymol 105:121-126
13. Sun Y, Oberley LW, Li Y (1988) A simple method for clinical assay of superoxide dismutase. Clin Chem 34:497-500
14. Flohe L, Gunzler WA (1984) Assays of glutathione peroxidase. Methods Enzymol 105:114-121
15. Draper HH, Hadley M (1990) Malondialdehyde determination as index of lipid peroxidation. Methods Enzymol 186:421-431
16. Goçer AI, Ildan F, Tuna M, Polat S, Tamer L, Kaya M (2001) Effects of trapidil on ATPase, lipid peroxidation with ultrastructure in experimental spinal cord injury. Neurosurg Res 24:136-142
17. Somuncu S, Cakmak MM, Erdogan S, Caglayan O, Akman H, Kaya M (2005) Trapidil, an inhibitor for phosphodiesterase and platalet-derived-growth-factor, amelioriates corrosive esophageal burn in rats. Tohoku J Exp Med 207:203-208
18. Colak, NaycI A, Polat G, Polat A, Comelekoglu U, Kanik A, Turkmenoglu O,Aydin S (2003) Effect of trapidil on the healing of colonic anastomoses in an experimental rat model. ANZ J Surg 73:916-921
19. Pompella A (1997) Biochemistry and histochemistry of oxidant stress and lipid peroxidation. Int J Vitam Nutr Res 67:289-297