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1
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33745299968
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Bacterial pneumonia, HIV therapy, and disease progression among HIV-infected women in the HIV epidemiologic research (HER) study
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The rate of bacterial pneumonia in HIV-infected women remains extremely high despite the introduction of ART
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Kohli R, Lo Y, Homel P, et al. Bacterial pneumonia, HIV therapy, and disease progression among HIV-infected women in the HIV epidemiologic research (HER) study. Clin Infect Dis 2006; 43:90-98. The rate of bacterial pneumonia in HIV-infected women remains extremely high despite the introduction of ART.
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(2006)
Clin Infect Dis
, vol.43
, pp. 90-98
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Kohli, R.1
Lo, Y.2
Homel, P.3
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2
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0037076755
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Guidelines for preventing opportunistic infections among HIV-infected persons: 2002 Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America
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Centers for Disease Control and Prevention
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Centers for Disease Control and Prevention: Guidelines for preventing opportunistic infections among HIV-infected persons: 2002 Recommendations of the U.S. Public Health Service and the Infectious Diseases Society of America. MMWR Morb Mortal Wkly Rep 2002, 51:1-52.
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(2002)
MMWR Morb Mortal Wkly Rep
, vol.51
, pp. 1-52
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3
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34848846869
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+ count less than 200 cells/μl.
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+ count less than 200 cells/μl.
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4
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33644754044
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Changes in invasive pneumococcal disease among HIV-infected adults living in the era of childhood pneumococcal immunization
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This cohort study suggested that the introduction of the pediatric pneumococcal conjugate vaccine has decreased the rate of invasive pneumococcal disease in HIV-infected adults
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Flannery B, Heffernan RT, Harrison LH, et al. Changes in invasive pneumococcal disease among HIV-infected adults living in the era of childhood pneumococcal immunization. Ann Intern Med 2006; 144:1-9. This cohort study suggested that the introduction of the pediatric pneumococcal conjugate vaccine has decreased the rate of invasive pneumococcal disease in HIV-infected adults.
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(2006)
Ann Intern Med
, vol.144
, pp. 1-9
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Flannery, B.1
Heffernan, R.T.2
Harrison, L.H.3
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5
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34447099008
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Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination
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Influenza is a common cause of febrile respiratory symptoms in HIV-infected patients receiving ART and presenting to an outpatient clinic for care despite high rates of prior influenza vaccination
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Klein MB, Lu Y, DelBalso L, et al. Influenzavirus infection is a primary cause of febrile respiratory illness in HIV-infected adults, despite vaccination. Clin Infect Dis 2007; 45:234-240. Influenza is a common cause of febrile respiratory symptoms in HIV-infected patients receiving ART and presenting to an outpatient clinic for care despite high rates of prior influenza vaccination.
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(2007)
Clin Infect Dis
, vol.45
, pp. 234-240
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Klein, M.B.1
Lu, Y.2
DelBalso, L.3
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6
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34250314931
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Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resourceconstrained settings: Informing urgent policy changes
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This paper presents a compelling argument for modification of national tuberculosis evaluation algorithms in HIV-infected patients
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Getahun H, Harrington M, O'Brien R, et al. Diagnosis of smear-negative pulmonary tuberculosis in people with HIV infection or AIDS in resourceconstrained settings: informing urgent policy changes. Lancet 2007; 369:2042-2049. This paper presents a compelling argument for modification of national tuberculosis evaluation algorithms in HIV-infected patients.
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(2007)
Lancet
, vol.369
, pp. 2042-2049
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Getahun, H.1
Harrington, M.2
O'Brien, R.3
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7
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33745096237
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Dowdy DW, Chaisson RE, Moulton LH, et al. The potential impact of enhanced diagnostic techniques for tuberculosis driven by HIV: a mathematical model. AIDS 2006; 20:751-762. A sophisticated mathematical analysis of the impact of a variety of diagnostic and public health measures on tuberculosis-control in areas of high HIV prevalence is presented.
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Dowdy DW, Chaisson RE, Moulton LH, et al. The potential impact of enhanced diagnostic techniques for tuberculosis driven by HIV: a mathematical model. AIDS 2006; 20:751-762. A sophisticated mathematical analysis of the impact of a variety of diagnostic and public health measures on tuberculosis-control in areas of high HIV prevalence is presented.
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8
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33644643266
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Guidelines for using the QuantiFERONTB Gold test for detecting Mycobacterium tuberculosis infection, United States
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Mazurek GH, Jereb J, Lobue P, et al. Guidelines for using the QuantiFERONTB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep 2005; 54:49-55.
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(2005)
MMWR Recomm Rep
, vol.54
, pp. 49-55
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Mazurek, G.H.1
Jereb, J.2
Lobue, P.3
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9
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34047231078
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Comparison of an interferon-gamma release assay with tuberculin skin testing in HIV-infected individuals
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The first large comparative study of TIGRA and TST performance in HIV-infected patients raises difficult questions about how to interpret discordant results between the two tests
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Luetkemeyer AF, Charlebois ED, Flores LL, et al. Comparison of an interferon-gamma release assay with tuberculin skin testing in HIV-infected individuals. Am J Respir Crit Care Med 2007; 175:737-742. The first large comparative study of TIGRA and TST performance in HIV-infected patients raises difficult questions about how to interpret discordant results between the two tests.
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(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 737-742
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Luetkemeyer, A.F.1
Charlebois, E.D.2
Flores, L.L.3
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10
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33750599208
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Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospot
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Jafari C, Ernst M, Kalsdorf B, et al. Rapid diagnosis of smear-negative tuberculosis by bronchoalveolar lavage enzyme-linked immunospot. Am J Respir Crit Care Med 2006; 174:1048-1054.
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(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 1048-1054
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Jafari, C.1
Ernst, M.2
Kalsdorf, B.3
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11
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33846222408
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Undiagnosed tuberculosis in a community with high HIV prevalence: Implications for tuberculosis control
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Wood R, Middelkoop K, Myer L, et al. Undiagnosed tuberculosis in a community with high HIV prevalence: implications for tuberculosis control. Am J Respir Crit Care Med 2007; 175:87-93.
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(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 87-93
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Wood, R.1
Middelkoop, K.2
Myer, L.3
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12
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34250822376
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The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil
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In spite of its retrospective design, this study provides a thought-provoking examination of the efficacy of IPT in HIV-infected patients
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Golub JE, Saraceni V, Cavalcante SC, et al. The impact of antiretroviral therapy and isoniazid preventive therapy on tuberculosis incidence in HIV-infected patients in Rio de Janeiro, Brazil. AIDS 2007; 21:1441-1448. In spite of its retrospective design, this study provides a thought-provoking examination of the efficacy of IPT in HIV-infected patients.
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(2007)
AIDS
, vol.21
, pp. 1441-1448
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Golub, J.E.1
Saraceni, V.2
Cavalcante, S.C.3
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13
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33845712173
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Reducing tuberculosis incidence by tuberculin skin testing, preventive treatment, and antiretroviral therapy in an area of low tuberculosis transmission
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Elzi L, Schlegel M, Weber R, et al. Reducing tuberculosis incidence by tuberculin skin testing, preventive treatment, and antiretroviral therapy in an area of low tuberculosis transmission. Clin Infect Dis 2007; 44:94-102.
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(2007)
Clin Infect Dis
, vol.44
, pp. 94-102
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Elzi, L.1
Schlegel, M.2
Weber, R.3
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14
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33646493800
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Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV-tuberculosis coinfected populations
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This paper presents an important discussion of the pros and cons of IPT for latent tuberculosis infection in HIV-infected persons
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Cohen T, Lipsitch M, Walensky RP, et al. Beneficial and perverse effects of isoniazid preventive therapy for latent tuberculosis infection in HIV-tuberculosis coinfected populations. Proc Natl Acad Sci U S A 2006; 103:7042-7047. This paper presents an important discussion of the pros and cons of IPT for latent tuberculosis infection in HIV-infected persons.
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(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 7042-7047
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Cohen, T.1
Lipsitch, M.2
Walensky, R.P.3
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15
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33750629139
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Gandhi NR, Moll A, Sturm AW, et al. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet 2006; 368:1575-1580. All HIV and tuberculosis specialists should be familiar with the specter of highly transmissable XDR tuberculosis described in this article, which may serve as a sentinel warning of a new and enormous challenge for tuberculosis control.
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Gandhi NR, Moll A, Sturm AW, et al. Extensively drug-resistant tuberculosis as a cause of death in patients co-infected with tuberculosis and HIV in a rural area of South Africa. Lancet 2006; 368:1575-1580. All HIV and tuberculosis specialists should be familiar with the specter of highly transmissable XDR tuberculosis described in this article, which may serve as a sentinel warning of a new and enormous challenge for tuberculosis control.
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16
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33749649080
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Microscopic-observation drug-susceptibility assay for the diagnosis of TB
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The MODS assay is a landmark development in the quest for tuberculosis diagnostics for the developing world
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Moore DA, Evans CA, Gilman RH, et al. Microscopic-observation drug-susceptibility assay for the diagnosis of TB. N Engl J Med 2006; 355: 1539-1550. The MODS assay is a landmark development in the quest for tuberculosis diagnostics for the developing world.
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(2006)
N Engl J Med
, vol.355
, pp. 1539-1550
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Moore, D.A.1
Evans, C.A.2
Gilman, R.H.3
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17
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34249818487
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Treatment outcomes of patients with HIV and tuberculosis
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In an era in which treatment shortening is in vogue, this paper explores the possibility that a different approach may be necessary in HIV-infected patients
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Nahid P, Gonzalez LC, Rudoy I, et al. Treatment outcomes of patients with HIV and tuberculosis. Am J Respir Crit Care Med 2007; 175:1199-1206. In an era in which treatment shortening is in vogue, this paper explores the possibility that a different approach may be necessary in HIV-infected patients.
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(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 1199-1206
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Nahid, P.1
Gonzalez, L.C.2
Rudoy, I.3
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18
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Administration of efavirenz (600 mg/day) with rifampicin results in highly variable levels but excellent clinical outcomes in patients treated for tuberculosis and HIV
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Friedland G, Khoo S, Jack C, et al. Administration of efavirenz (600 mg/day) with rifampicin results in highly variable levels but excellent clinical outcomes in patients treated for tuberculosis and HIV. J Antimicrob Chemother 2006; 58:1299-1302.
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(2006)
J Antimicrob Chemother
, vol.58
, pp. 1299-1302
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Friedland, G.1
Khoo, S.2
Jack, C.3
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19
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33646347882
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Virological response to highly active antiretroviral therapy is unaffected by antituberculosis therapy
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Breen RA, Miller RF, Gorsuch T, et al. Virological response to highly active antiretroviral therapy is unaffected by antituberculosis therapy. J Infect Dis 2006; 193:1437-1440.
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(2006)
J Infect Dis
, vol.193
, pp. 1437-1440
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Breen, R.A.1
Miller, R.F.2
Gorsuch, T.3
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20
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33847156425
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Timing of antiretroviral therapy initiation in tuberculosis patients with AIDS: A decision analysis
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In a hypothesis-generating study, the authors find that the consequences of delaying ART in HIV-tuberculosis co-infection may outweigh the benefits
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Schiffer JT, Sterling TR. Timing of antiretroviral therapy initiation in tuberculosis patients with AIDS: a decision analysis. J Acquir Immune Defic Syndr 2007; 44:229-234. In a hypothesis-generating study, the authors find that the consequences of delaying ART in HIV-tuberculosis co-infection may outweigh the benefits.
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(2007)
J Acquir Immune Defic Syndr
, vol.44
, pp. 229-234
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Schiffer, J.T.1
Sterling, T.R.2
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21
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33646059534
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Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients
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Bourgarit A, Carcelain G, Martinez V, et al. Explosion of tuberculin-specific Th1-responses induces immune restoration syndrome in tuberculosis and HIV co-infected patients. AIDS 2006; 20:F1-F7.
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(2006)
AIDS
, vol.20
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Bourgarit, A.1
Carcelain, G.2
Martinez, V.3
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22
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33846624283
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Tuberculosis-associated immune reconstitution disease: Incidence, risk factors and impact in an antiretroviral treatment service in South Africa
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A postulated mechanism for IRIS raises the question, can a diagnostic test for IRIS be far behind
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Lawn SD, Myer L, Bekker LG, et al. Tuberculosis-associated immune reconstitution disease: incidence, risk factors and impact in an antiretroviral treatment service in South Africa. AIDS 2007; 21:335-341. A postulated mechanism for IRIS raises the question, can a diagnostic test for IRIS be far behind?
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(2007)
AIDS
, vol.21
, pp. 335-341
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Lawn, S.D.1
Myer, L.2
Bekker, L.G.3
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23
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34547629992
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Friedland G, Churchyard GJ, Nardell E. Tuberculosis and HIV coinfection: current state of knowledge and research priorities. J Infect Dis 2007; 196 (Suppl 1):S1-S3. The conveners of an expert symposium on HIV-tuberculosis co-infection introduce an excellent supplemental issue to the Journal of Infectious Diseases, which provides current overviews of the most important issues in the field.
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Friedland G, Churchyard GJ, Nardell E. Tuberculosis and HIV coinfection: current state of knowledge and research priorities. J Infect Dis 2007; 196 (Suppl 1):S1-S3. The conveners of an expert symposium on HIV-tuberculosis co-infection introduce an excellent supplemental issue to the Journal of Infectious Diseases, which provides current overviews of the most important issues in the field.
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24
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33751248769
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Huang L, Morris A, Limper AH, et al. An Official ATS Workshop Summary: Recent advances and future directions in pneumocystis pneumonia (PCP). Proc Am Thorac Soc 2006; 3:655-664. This is a concise overview of recent advances in PCP.
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Huang L, Morris A, Limper AH, et al. An Official ATS Workshop Summary: Recent advances and future directions in pneumocystis pneumonia (PCP). Proc Am Thorac Soc 2006; 3:655-664. This is a concise overview of recent advances in PCP.
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25
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36349024281
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Pneumocystis jirovecii pneumonia and other pulmonary infections in TB smear-negative HIV-positive patients with atypical chest X-ray in Ethiopia
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This report highlights the frequency of bacterial pneumonia and PCP in HIV-infected patients in Africa who are sputum smear negative for acid-fast bacilli
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Aderaye G, Bruchfeld J, Aseffa G, et al. Pneumocystis jirovecii pneumonia and other pulmonary infections in TB smear-negative HIV-positive patients with atypical chest X-ray in Ethiopia. Scand J Infect Dis 2007; 39:1045-1053. This report highlights the frequency of bacterial pneumonia and PCP in HIV-infected patients in Africa who are sputum smear negative for acid-fast bacilli.
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(2007)
Scand J Infect Dis
, vol.39
, pp. 1045-1053
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Aderaye, G.1
Bruchfeld, J.2
Aseffa, G.3
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26
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33745822758
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Pneumocystis jirovecii pneumonia in African miners at autopsy
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This extremely comprehensive autopsy study of African miners documents a high rate of unsuspected PCP and presumably HIV before death
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Wong ML, Back P, Candy G, et al. Pneumocystis jirovecii pneumonia in African miners at autopsy. Int J Tuberc Lung Dis 2006; 10:756-760. This extremely comprehensive autopsy study of African miners documents a high rate of unsuspected PCP and presumably HIV before death.
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(2006)
Int J Tuberc Lung Dis
, vol.10
, pp. 756-760
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Wong, M.L.1
Back, P.2
Candy, G.3
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27
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34547728802
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+ count remains under 200 cells/μl.
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+ count remains under 200 cells/μl.
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28
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43149110111
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Huggett JF, Taylor MS, Kocjan G, et al. Development and evaluation of a real-time PCR assay for detection of Pneumocystis jirovecii DNA in bronchoalveolar lavage fluid of HIV-infected patients. Thorax 2007; 10 Aug [Epub ahead of print]. This paper describes a novel means of PCP diagnosis based on a PCR assay utilizing primers to the heat shock protein 70 gene.
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Huggett JF, Taylor MS, Kocjan G, et al. Development and evaluation of a real-time PCR assay for detection of Pneumocystis jirovecii DNA in bronchoalveolar lavage fluid of HIV-infected patients. Thorax 2007; 10 Aug [Epub ahead of print]. This paper describes a novel means of PCP diagnosis based on a PCR assay utilizing primers to the heat shock protein 70 gene.
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29
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2042503030
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Prevalence and clinical predictors of Pneumocystis colonization among HIV-infected men
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Morris A, Kingsley LA, Groner G, et al. Prevalence and clinical predictors of Pneumocystis colonization among HIV-infected men. AIDS 2004; 18:793-798.
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(2004)
AIDS
, vol.18
, pp. 793-798
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Morris, A.1
Kingsley, L.A.2
Groner, G.3
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30
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4544240074
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Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization
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Morris A, Sciurba FC, Lebedeva IP, et al. Association of chronic obstructive pulmonary disease severity and Pneumocystis colonization. Am J Respir Crit Care Med 2004; 170:408-413.
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(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 408-413
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Morris, A.1
Sciurba, F.C.2
Lebedeva, I.P.3
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31
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33947122772
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Norris KA, Morris A, Patil S, et al. Pneumocystis colonization, airway inflammation, and pulmonary function decline in acquired immunodeficiency syndrome. Immunol Res 2006; 36:175-187. This excellent review describes the association between Pneumocystis colonization and obstructive lung disease.
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Norris KA, Morris A, Patil S, et al. Pneumocystis colonization, airway inflammation, and pulmonary function decline in acquired immunodeficiency syndrome. Immunol Res 2006; 36:175-187. This excellent review describes the association between Pneumocystis colonization and obstructive lung disease.
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32
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0037415026
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Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia
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Morris A, Wachter RM, Luce J, et al. Improved survival with highly active antiretroviral therapy in HIV-infected patients with severe Pneumocystis carinii pneumonia. AIDS 2003; 17:73-80.
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(2003)
AIDS
, vol.17
, pp. 73-80
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Morris, A.1
Wachter, R.M.2
Luce, J.3
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33
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33747067973
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Improved survival for HIV infected patients with severe Pneumocystis jirovecii pneumonia is independent of highly active antiretroviral therapy
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This article shows that mortality from severe PCP requiring ICU care has decreased over time but is independent of ART, suggesting that other factors such as low tidal ventilation for acute respiratory distress syndrome and fluid conservative management may be responsible
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Miller RF, Allen E, Copas A, et al. Improved survival for HIV infected patients with severe Pneumocystis jirovecii pneumonia is independent of highly active antiretroviral therapy. Thorax 2006; 61:716-721. This article shows that mortality from severe PCP requiring ICU care has decreased over time but is independent of ART, suggesting that other factors such as low tidal volume ventilation for acute respiratory distress syndrome and fluid conservative management may be responsible.
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(2006)
Thorax
, vol.61
, pp. 716-721
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Miller, R.F.1
Allen, E.2
Copas, A.3
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34
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29744464688
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Current issues in critical care of the human immunodeficiency virus-infected patient
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This is an overview of the changing epidemiology of HIV-infected patients in the ICU during the ART era
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Morris A, Masur H, Huang L. Current issues in critical care of the human immunodeficiency virus-infected patient. Crit Care Med 2006; 34:42-49. This is an overview of the changing epidemiology of HIV-infected patients in the ICU during the ART era.
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(2006)
Crit Care Med
, vol.34
, pp. 42-49
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Morris, A.1
Masur, H.2
Huang, L.3
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35
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33745881035
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Intensive care of patients with HIV infection
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This review focuses on use of ART in the ICU. The article includes a useful clinical algorithm that provides a framework for making decisions regarding use of ART in the ICU
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Huang L, Quartin A, Jones D, et al. Intensive care of patients with HIV infection. N Engl J Med 2006; 355:173-181. This review focuses on use of ART in the ICU. The article includes a useful clinical algorithm that provides a framework for making decisions regarding use of ART in the ICU.
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(2006)
N Engl J Med
, vol.355
, pp. 173-181
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Huang, L.1
Quartin, A.2
Jones, D.3
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