Radiosynthesis of (S)-5-methoxymethyl-3-[6-(4,4,4-trifluorobutoxy)benzo[d] isoxazol-3-yl] oxazolidin-2-[11C]one ([11C]SL25.1188), a novel radioligand for imaging monoamine oxidase-B with PET

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 51, Issue 3, 2008, Pages 153-158

  Bramoullé, Yann ^a   Puech, Frédéric ^b   Saba, Wadad ^a   Valette, Heric ^a   Bottlaender, Michel ^a   George, Pascal ^b   Dollé, Frédéric ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

^b SANOFI   (France)

Author keywords

Carbon 11; MAO B; Phosgene; SL25.1188

Indexed keywords

CARBON; POSITRON EMISSION TOMOGRAPHY; RATS;

2-OXAZOLIDINONE; CARBON-11; MAO-B; METHOXYMETHYL; MONOAMINE OXIDASE B; NOVEL SERIES; PHOSGENE; RADIOLIGANDS; RADIOSYNTHESIS; SL25.1188;

DICHLOROMETHANE;

5 METHOXYMETHYL 3 [6 (4,4,4 TRIFLUOROBUTOXY)BENZO[D]ISOXAZOL 3 YL]OXAZOLIDIN 2 ONE; 5 METHOXYMETHYL 3 [6 (4,4,4 TRIFLUOROBUTOXY)BENZO[D]ISOXAZOL 3 YL]OXAZOLIDIN 2 ONE C 11; AMINE OXIDASE (FLAVIN CONTAINING) ISOENZYME B; CARBON 11; DICHLOROMETHANE; MONOAMINE OXIDASE B INHIBITOR; PHOSGENE; RADIOLIGAND; SL 25 1188;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; ISOTOPE LABELING; POSITRON EMISSION TOMOGRAPHY; RADIOCHEMISTRY; REACTION ANALYSIS; RING OPENING;

RATTUS;

EID: 43149090069     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1492     Document Type: Article

References (72)