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Volumn 21, Issue 3, 2008, Pages 323-331

Management of congenital diaphragmatic hernia

Author keywords

Congenital diaphragmatic hernia; Management; Outcome; Treatment

Indexed keywords

ILOPROST; NITRIC OXIDE; PROSTAGLANDIN; SILDENAFIL;

EID: 43149084797     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/ACO.0b013e3282f9e214     Document Type: Review
Times cited : (27)

References (128)
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    • Lin AE, Pober BR, Adatia I. Congenital diaphragmatic hernia and associated cardiovascular malformations type, frequency, and impact on management. Am J Med Genet C Semin Med Genet 2007; 145:201-216. An important review of the literature revealing an 11-15% incidence of cardiovascular abnormality associated with isolated CDH. Although the defect types have a similar incidence as the general population, the combination has a poorer prognosis than either malformation alone. The impact of added chromosomal defects could not be determined from the available data.
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    • Fetal lung-head ratio is not related to outcome for antenatal diagnosed congenital diaphragmatic hernia
    • A further study showing that an LHR less than 1.0 or a liver herniation is not sensitive prognosticator for fetal intervention
    • Arkovitz MS, Russo M, Devine P. Fetal lung-head ratio is not related to outcome for antenatal diagnosed congenital diaphragmatic hernia. J Pediatr Surg 2007; 42:107-110. A further study showing that an LHR less than 1.0 or a liver herniation is not sensitive prognosticator for fetal intervention.
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    • How useful is the lung to head ratio in predicting outcome in the fetus with congenital diaphragmatic hernia? A systematic review and meta-analysis
    • An excellent review based on current evidence for LHR; most studies were done before normal data were reported and thus do not support the prognostic validity of LHR
    • Ba'ath ME, Jesudason EC, Losty PD. How useful is the lung to head ratio in predicting outcome in the fetus with congenital diaphragmatic hernia? A systematic review and meta-analysis. Ultrasound Obstet Gynecol 2007; 30:897-906. An excellent review based on current evidence for LHR; most studies were done before normal data were reported and thus do not support the prognostic validity of LHR.
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    • Predictive value of lung-head ratio in congenital diaphragmatic hernia
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    • Yang SH, Nobuhara KK, Keller RL, et al. Reliability of the lung-to-head ratio as a predictor of outcome in fetuses with isolated left congenital diaphragmatic hernia at gestation outside 24-26 weeks. Am J Obstet Gynecol 2007; 197:30.e1-30.e7. First retrospective cross-sectional study from renowned Fetal Treatment Center database to show the linear relationship of LHR 24-34 weeks, gestation but less reliable from 20 to 24 weeks in 107 fetuses. LHR of at least 0.97 predicted survival.
    • Yang SH, Nobuhara KK, Keller RL, et al. Reliability of the lung-to-head ratio as a predictor of outcome in fetuses with isolated left congenital diaphragmatic hernia at gestation outside 24-26 weeks. Am J Obstet Gynecol 2007; 197:30.e1-30.e7. First retrospective cross-sectional study from renowned Fetal Treatment Center database to show the linear relationship of LHR 24-34 weeks, gestation but less reliable from 20 to 24 weeks in 107 fetuses. LHR of at least 0.97 predicted survival.
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    • Jani J, Nicolaides KH, Keller RL, et al. Antenatal-CDH-Registry Group Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia. Ultrasound Obstet Gynecol 2007; 30:67-71. The first report comparing normal LHR values, established from 652 fetuses, with data from 352 isolated CDH fetuses. LHR increases with gestational age but the observed-to-expected change remains the same irrespective of gestational age and is a useful predictor of subsequent survival.
    • Jani J, Nicolaides KH, Keller RL, et al. Antenatal-CDH-Registry Group Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia. Ultrasound Obstet Gynecol 2007; 30:67-71. The first report comparing normal LHR values, established from 652 fetuses, with data from 352 isolated CDH fetuses. LHR increases with gestational age but the observed-to-expected change remains the same irrespective of gestational age and is a useful predictor of subsequent survival.
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    • Defect size determines survival in infants with congenital diaphragmatic hernia
    • The size of the diaphragmatic defect, possibly a surrogate marker for pulmonary hypoplasia, was shown to adversely affect the outcome in this prospective multicentre cohort study of 3062 live born CDH. Congenital Diaphragmatic Hernia Study Group
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