Methods and applications for marker-free quantitative digital holographic phase contrast imaging in life cell analysis

Proceedings of SPIE - The International Society for Optical Engineering

Volumn 6796, Issue , 2008, Pages

  Kemper, Björn ^a   Langehanenberg, Patrik ^a   Von Bally, Gert ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Digital holographic microscopy; Life cell analysis; Microscopy

Indexed keywords

BIOMARKERS; CELLS; HOLOGRAMS; HOLOGRAPHIC INTERFEROMETRY; IMAGE RECONSTRUCTION;

DIGITAL HOLOGRAPHY; NON-DESTRUCTIVE TESTING;

HOLOGRAPHIC GRATINGS;

EID: 43149083716     PISSN: 0277786X     EISSN: None     Source Type: Conference Proceeding    
DOI: 10.1117/12.778093     Document Type: Conference Paper

References (14)

1. T. Kreis, Holographic Interferometry: Principles and Methods. Akademie-Publishing, Berlin, 1996.
2. V. P. Shchepinov, V. S. Pisarev, Strain and Stress Analysis by Holographic and Speckle Interferometry. John Wiley & Sons, Chichester, 1996.
3. M.-A. Beek, W. Hentschel, "Laser metrology - a diagnostic tool in automotive industry", Opt. Lasers Eng. 34, 101-120 (2000).
4. E. Cuche, P. Marquet C. Depeursinge, "Simultaneous amplitude-contrast and quantitative phase contrast microscopy by numerical reconstruction of Fresnel off-axis holograms", Appl. Opt. 38, 6694-7001 (1999).
5. P. Marquet, B. Rappaz, P. J. Magistretti, E. Cuche, Y. Emery, T. Colomb, C. Depeursinge, "Digital holographic microscopy: a noninvasive contrast imaging technique allowing quantitative visualization of living cells with sub wavelength accuracy", Opt. Lett. 30, 468-470 (2005).
6. B. Kemper, D. Carl, A. Höink, G. von Bally, I. Bredebusch, and J. Schnekenburger, "Modular digital holographic microscopy system for marker-free quantitative phase contrast imaging of living cells, Proc. SPIE 6191 (2006).
7. D. Carl, B. Kemper, G. Wernicke, G. von Bally, "Parameter-optimized digital holographic microscope for high resolution living cell analysis", Appl. Opt. 43, 6536-6544 (2004).
8. G. von Bally, B. Kemper et al.: New ways for marker-free life cell and tumor analysis, in: J. Popp, M. Strehle (Eds.): Biophotonics: visions for a better health care, Wiley, 301-360, 2006.
9. U. Schnars, W. Jüptner, "Direct recording of holograms by a CCD target and numerical reconstruction," Appl. Opt. 33, 179-181 (1994).
10. M. Liebling, T. Blu, M. Unser, "Complex-wave retrieval from a single off-axis hologram", J. Opt. Soc Am. A 21, 367-377 (2004).
11. T. M. Kreis, M. Adams, W. P. O. Jüptner, "Methods of digital holography: A comparison", Proc. SPIE 3098, 224-233 (1997).
12. B. Kemper, D. Carl, J. Schnekenburger, I. Bredebusch, M. Schäfer, W. Domschke, G. von Bally, "Investigation of living pancreas tumor cells by digital holographic microscopy", J. Bio. Opt. 11 034005 (2006).
13. J. Schnekenburger, J. Mayerle, B. Krüger, I. Buchwalow, F. U. Weiss, E. Albrecht,V. E. Samoilova, W. Domschke, M. M. Lerch, "Protein tyrosine phosphatase k and SHP-1 are involved in the regulation of cell-cell contacts at adherens junctions in the exocrine pancreas ", Gut 54, 1445-1455 (2005.)
14. P. Langehanenberg, B. Kemper, G. von Bally, "Autofocus algorithms for digital-holographic microscopy", Proc. SPIE 6633 (in press).