3′-Sulfonylesters of 2,5′-anhydro-1-(2-deoxy-β-d-threo-pentofuranosyl)thymine as precursors for the synthesis of [18F]FLT: syntheses and radiofluorination trials

Nuclear Medicine and Biology

Volumn 35, Issue 4, 2008, Pages 413-423

  Windhorst, Albert D ^a   Klein, Pieter J ^a   Eisenbarth, Joseph ^b   Oeser, Thomas ^c   Kruijer, Perry S ^d   Eisenhut, Michael ^b  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

Author keywords

2,5 Anhydro 1 (2 deoxy d threo pentofuranosyl)thymine; 3 Sulfonylesters; 18F FLT; Radioflurination

Indexed keywords

2,5 ANHYDRO 1 (2 DEOXY 3 (4 NITROBENZENESULFONYL) BETA DEXTRO THREO PENTOFURANOSYL)THYMINE; 2,5 ANHYDRO 1 (2 DEOXY BETA DEXTRO THREO PENTOFURANOSYL)THYMINE; 2,5 ANHYDRO 1( 2 DEOXY 3 (2,2,2 TRIFLUOROETHANESULFONYL) BETA DEXTRO THREO PENTOFURANOSYL)THYMINE; 2,5 ANHYDRO 1( 2 DEOXY 3 (TOLUENESULFONYL) BETA DEXTRO THREO PENTOFURANOSYL)THYMINE; 3' SULFONYLESTER; FLUOROTHYMIDINE F18; RADIOPHARMACEUTICAL AGENT; SODIUM HYDROXIDE; SULFONIC ACID DERIVATIVE; THYMINE DERIVATIVE; 1 (2' DEOXY BETA THREOPENTOFURANOSYL)THYMINE; 1-(2'-DEOXY-BETA-THREOPENTOFURANOSYL)THYMINE; 2',3' DIDEOXYNUCLEOSIDE DERIVATIVE; 3' FLUOROTHYMIDINE; ACID ANHYDRIDE; ALKANESULFONIC ACID; DRUG DERIVATIVE; FLUORINE; THYMIDINE;

ARTICLE; FLUORINATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; MELTING POINT; NUCLEAR MAGNETIC RESONANCE; SYNTHESIS; THIN LAYER CHROMATOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; ISOTOPE LABELING; METHODOLOGY;

ALKANESULFONATES; ANHYDRIDES; DIDEOXYNUCLEOSIDES; FLUORINE RADIOISOTOPES; ISOTOPE LABELING; MOLECULAR STRUCTURE; RADIOPHARMACEUTICALS; THYMIDINE;

EID: 43049176219     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2008.02.012     Document Type: Article

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