Cytogenetic and molecular cytogenetic findings in lipoblastoma

Cancer Genetics and Cytogenetics

Volumn 183, Issue 1, 2008, Pages 60-63

  Bartuma, Hammurabi ^a   Domanski, Henryk A ^a   Von Steyern, Fredrik Vult ^a   Kullendorff, Carl Magnus ^a   Mandahl, Nils ^a   Mertens, Fredrik ^a  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CHROMOSOME 8Q; CLINICAL ARTICLE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE; GENE REARRANGEMENT; HUMAN; HUMAN TISSUE; INFANT; KARYOTYPE; LIPOBLASTOMA; MALE; PLAG1 GENE; PRESCHOOL CHILD; PRIORITY JOURNAL;

ABDOMINAL WALL; BUTTOCKS; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 11; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 8; DNA-BINDING PROTEINS; FEMALE; HUMANS; INFANT; KARYOTYPING; LIPOMA; MALE; MOLECULAR DIAGNOSTIC TECHNIQUES; THIGH; THORACIC WALL;

EID: 43049173411     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cancergencyto.2008.01.017     Document Type: Article

References (15)

1. Sciot R., and Mandahl N. Lipoblastoma/lipoblastomatosis. In: Fletcher C.D.M., Unni K.K., and Mertens F. (Eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Soft Tissue and Bone (2002), IARC Press, Lyon 26-27
2. Sandberg A.A., Gibas Z., Saren E., Li F.P., Limon J., and Tebbi C.K. Chromosome abnormalities in two benign adipose tumors. Cancer Genet Cytogenet 22 (1986) 55-61
3. Mitelman Database of Chromosome Aberrations in Cancer 2007. Mitelman F, Johansson B, Mertens F, editors. Available at: http://www.cgap.nci.nih.gov/Chromosomes/Mitelman. Accessed on November 1, 2007.
4. Gisselsson D., Hibbard M.K., Dal Cin P., Sciot R., Hsi B.L., Kozakewich H.P., and Fletcher J.A. PLAG1 alterations in lipoblastoma: involvement in varied mesenchymal cell types and evidence for alternative oncogenic mechanisms. Am J Pathol 159 (2001) 955-962
5. Hibbard M.K., Kozakewich H.P., Dal Cin P., Sciot R., Tan X., Xiao S., and Fletcher J.A. PLAG1 fusion oncogenes in lipoblastoma. Cancer Res 60 (2000) 4869-4872
6. Bartuma H., Hallor K.H., Panagopoulos I., Collin A., Rydholm A., Gustafson P., Bauer H.C.F., Brosjö O., Domanski H.A., Mandahl N., and Mertens F. Assessment of the clinical and molecular impact of different cytogenetic subgroups in a series of 272 lipomas with abnormal karyotype. Genes Chromosomes Cancer 46 (2007) 594-606
7. Antonescu C., and Ladanyi M. Myxoid liposarcoma. In: Fletcher C.D.M., Unni K.K., and Mertens F. (Eds). World Health Organization Classification of TumoursPathology and Genetics of Tumours of Soft Tissue and Bone (2002), IARC Press, Lyon 40-43
8. Mandahl N., Heim S., Arheden K., Rydholm A., Willén H., and Mitelman F. Three major cytogenetic subgroups can be identified among chromosomally abnormal solitary lipomas. Hum Genet 79 (1988) 203-208
9. Dahlén A., Debiec-Rychter M., Pedeutour F., Domanski H.A., Höglund M., Bauer H.C.F., Rydholm A., Sciot R., Mandahl N., and Mertens F. Clustering of deletions on chromosome 13 in benign and low-malignant lipomatous tumors. Int J Cancer 103 (2003) 616-623
10. Morerio C., Rapella A., Rosanda C., Tassano E., Gambini C., Romagnoli G., and Panarello C. PLAG1-HAS2 fusion in lipoblastoma with masked 8q intrachromosomal rearrangement. Cancer Genet Cytogenet 156 (2005) 183-184
11. Sciot R., De Wever I., and Debiec-Rychter M. Lipoblastoma in a 23-year-old male: distinction from atypical lipomatous tumor using cytogenetic and fluorescence in-situ hybridization analysis. Virchows Arch 442 (2003) 468-471
12. Bourelle S., Viehweger E., Launay F., Quilichini B., Bouvier C., Hagemeijer A., Jouve J.-L., and Bollini G. Lipoblastoma and lipoblastomatosis. J Pediatr Orthop B 15 (2006) 356-361
13. Brandal P., Bjerkehagen B., and Heim S. Rearrangement of chromosomal region 8q11-13 in lipomatous tumours: correlation with lipoblastoma morphology. J Pathol 208 (2006) 388-394
14. Lee Y.S., and Dutta A. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. Genes Dev 21 (2007) 1025-1030
15. Mayr C., Hemann M.T., and Bartel D.P. Disrupting the pairing between let-7 and Hmga2 enhances oncogenic transformation. Science 315 (2007) 1576-1579