Radiotherapy After Prostatectomy: Is the Evidence for Dose Escalation out There?

International Journal of Radiation Oncology Biology Physics

Volumn 71, Issue 2, 2008, Pages 346-350

  King, Christopher R ^a   Kapp, Daniel S ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Dose escalation; Dose response; Postoperative radiotherapy; Prostate cancer

Indexed keywords

BIOMEDICAL ENGINEERING; DISEASE CONTROL; DOSIMETRY; HOSPITAL DATA PROCESSING; ONCOLOGY;

DOSE ESCALATION; DOSE RESPONSE; POSTOPERATIVE RADIOTHERAPY; PROSTATE CANCER;

RADIOTHERAPY;

ARTICLE; CANCER RADIOTHERAPY; CANCER SURVIVAL; CONTROLLED STUDY; DOSE RESPONSE; HUMAN; MAJOR CLINICAL STUDY; POSTOPERATIVE CARE; PRIORITY JOURNAL; PROSTATE CANCER; PROSTATECTOMY; RADIATION DOSE;

ALGORITHMS; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; MALE; NEOPLASM, RESIDUAL; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS; RADIOTHERAPY, ADJUVANT; SALVAGE THERAPY;

EID: 43049171639     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.10.008     Document Type: Article

References (28)

1. Bolla M., van Poppel H., Collette L., et al. Postoperative radiotherapy after radical prostatectomy: A randomized controlled trial (EORTC trial 22911). Lancet 366 (2005) 572-578
2. Thompson I.M., Tangen C.M., Paradelo J., et al. Adjuvant radiotherapy for pathologically advanced prostate cancer: A randomized trial. JAMA 296 (2006) 2329-2335
3. Stephenson A.J., Scardino P.T., Kattan M.W., et al. Predicting the outcome of salvage radiation therapy for recurrent prostate cancer after radical prostatectomy. J Clin Oncol 25 (2007) 2035-2041
4. Hayes S.B., and Pollack A. Parameters for treatment decisions for salvage radiation therapy. J Clin Oncol 23 (2005) 8204-8211
5. Cox J.D., Gallagher M.J., Hammond E.H., et al., ASTRO Consensus Panel. Consensus statement on radiation therapy of prostate cancer: Guidelines for prostate re-biopsy after radiation and for radiation therapy with rising PSA levels after radical prostatectomy. J Clin Oncol 17 (1999) 1155-1163
6. Pollack A., Zagars G.K., Starkschall G., et al. Prostate cancer radiation dose-response: Results of the M. D. Anderson phase III randomized trial. Int J Radiat Oncol Biol Phys 53 (2002) 1097-1105
7. Zietman A.L., DeSilvio M.L., Slater J.D., et al. Comparison of conventional-dose vs high-dose conformal radiation therapy in clinically localized adenocarcinoma of the prostate: A randomized controlled trial. JAMA 294 (2005) 1233-1239
8. Eade T.N., Hanlon A.L., Horwitz E.M., et al. What dose of external beam radiation is high enough for prostate cancer?. Int J Radiat Oncol Biol Phys 68 (2007) 682-689
9. Zelefsky M.J., Leibel S.A., Gaudin P.B., et al. Dose-escalation with three-dimensional conformal radiation therapy affects the outcome in prostate cancer. Int J Radiat Oncol Biol Phys 41 (1998) 491-500
10. Valicenti R.K., Gomella L.G., Ismail M., et al. Effect of higher radiation dose on biochemical control after radical prostatectomy for pT3N0 prostate cancer. Int J Radiat Oncol Biol Phys 42 (1998) 501-506
11. Anscher M.S., Clough R., and Dodge R. Radiotherapy for a rising PSA after radical prostatectomy: The first 10 years. Int J Radiat Oncol Biol Phys 48 (2000) 369-375
12. King C.R., and Spiotto M.T. Improved outcomes with higher doses for salvage radiotherapy after prostatectomy. Int J Radiat Oncol Biol Phys 71 (2008) 23-27
13. Swanson G.P., Hussey M.A., Tangen C.M., et al. Predominant treatment failure in post-prostatectomy patients is local: Analysis of patterns of treatment failure in SWOG 8794. J Clin Oncol 25 (2007) 2225-2229
14. Coen J.J., Zietman A.L., Thakral H., et al. Radical radiation for localized prostate cancer: Local persistence of disease results in a late wave of metastases. J Clin Oncol 20 (2002) 3199-3205
15. Cox J.D., Grignon D., Kaplan R., et al. Consensus statement: Guidelines for PSA following radiation therapy. Int J Radiat Oncol Biol Phys 37 (1997) 1035-1041
16. Fowler J.F., Ritter M.A., Chappell R.J., et al. What hypofractionated protocols should be tested for prostate cancer?. Int J Radiat Oncol Biol Phys 56 (2003) 1093-1104
17. Catton C., Gospodarowicz M., Mui J., et al. Clinical and biochemical outcome of conventional dose radiotherapy for localized prostate cancer. Can J Urol 9 (2002) 1444-1452
18. Okunieff P., Morgan D., Niemierko A., et al. Radiation dose-response of human tumors. Int J Radiat Oncol Biol Phys 32 (1995) 1227-1237
19. Catton C., Gospodarowicz M., Warde P., et al. Adjuvant and salvage radiation therapy after radical prostatectomy for adenocarcinoma of the prostate. Radiother Oncol 59 (2001) 51-60
20. Tsien C., Griffith K.A., Sandler H.A., et al. Long-term results of three-dimensional conformal adjuvant and salvage radiotherapy after radical prostatectomy. Urology 62 (2003) 93-98
21. Taylor N., Kelly J.F., Kuban D.A., et al. Adjuvant and salvage radiotherapy after radical prostatectomy for prostate cancer. Int J Radiat Oncol Biol Phys 56 (2003) 755-763
22. Chawla A.K., Thakral H.K., Zietman A.L., et al. Salvage radiotherapy after radical prostatectomy for prostate adenocarcinoma: Analysis of efficacy and prognostic factors. Urology 59 (2002) 726-731
23. Buskirk S.J., Pisansky T.M., Schild S.E., et al. Salvage radiotherapy for isolated prostate specific antigen increase after radical prostatectomy: Evaluation of prognostic factors and creation of a prognostic scoring system. J Urol 176 (2006) 985-990
24. Kalapurakal J.A., Huang C.-F., Neriamparampil M.M., et al. Biochemical disease-free survival following adjuvant and salvage irradiation after radical prostatectomy. Int J Radiat Oncol Biol Phys 54 (2002) 1047-1054
25. Stamey T., Kabalin J., McNeal J., et al. Prostate specific antigen in the diagnosis and treatment of adenocarcinoma of the prostate. II. Radical prostatectomy treated patients. J Urol 141 (1998) 1076-1083
26. Feng M., Hanlon A.L., Pisansky T.M., et al. Predictive factors for late genitourinary and gastrointestinal toxicity in patients with prostate cancer treated with adjuvant or salvage radiotherapy. Int J Radiat Oncol Biol Phys 68 (2007) 1417-1423
27. Schiffner D.C., Gottschalk A.R., Lometti M., et al. Daily electronic portal imaging of implanted gold seed fiducials in patients undergoing radiotherapy after radical prostatectomy. Int J Radiat Oncol Biol Phys 67 (2007) 610-619
28. King C.R., Presti Jr. J.C., Gill H., et al. Radiotherapy after radical prostatectomy: Does transient androgen suppression improve outcomes?. Int J Radiat Oncol Biol Phys 59 (2004) 341-347