Synthesis, properties, and perspectives of gem-diphosphono substituted-thiazoles

European Journal of Medicinal Chemistry

Volumn 43, Issue 5, 2008, Pages 1015-1024

  Abdou, Wafaa M ^a   Ganoub, Neven A ^a   Geronikaki, Athina ^b   Sabry, Eman ^a  

^a NATIONAL RESEARCH CENTRE   (Egypt)

^b ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

Author keywords

Phosphonate carbanions; Bone resorption; Chronic inflammation; Drug research; Heteroarylmethylene 1,1 bisphosphonates

Indexed keywords

BISPHOSPHONIC ACID DERIVATIVE; METHYLENEBISPHOSPHONATE DERIVATIVE; PHOSPHORUS; REAGENT; TETRAETHYL METHYL 1,1 BISPHOSPHONATE; THIAZOLE DERIVATIVE; WITTIG HORNER REAGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; MICHAEL ADDITION; NONHUMAN; OSTEOLYSIS; PHOSPHORUS NUCLEAR MAGNETIC RESONANCE; PREDICTION; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION; STRUCTURE ANALYSIS; THIN LAYER CHROMATOGRAPHY;

ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BONE DENSITY CONSERVATION AGENTS; BONE RESORPTION; CHRONIC DISEASE; DIPHOSPHONATES; GRANULOMA; HYPERSENSITIVITY, DELAYED; INFLAMMATION; MICE; RATS; STRUCTURE-ACTIVITY RELATIONSHIP; THIAZOLES;

EID: 43049164225     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.07.005     Document Type: Article

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