Striatal dopaminergic terminals in type 1 and type 2 alcoholics measured with [3H]dihydrotetrabenazine and human whole hemisphere autoradiography

Psychiatry Research - Neuroimaging

Volumn 163, Issue 1, 2008, Pages 70-75

  Tupala, Erkki ^a,b   Häkkinen, Merja ^a   Storvik, Markus ^b   Tiihonen, Jari ^a  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b University of Kuopio ^*  (Finland)

Author keywords

Alcohol induced disorders; Dopamine; Ethanol induced nervous system disorders; Human brain; Transporters

Indexed keywords

DIHYDROTETRABENAZINE H 3; DOPAMINE TRANSPORTER; RADIOLIGAND;

ADULT; ALCOHOLISM; ARTICLE; AUTORADIOGRAPHY; BRAIN LEVEL; BRAIN TISSUE; CADAVER; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; CORPUS STRIATUM; DOPAMINERGIC NERVE CELL; DOPAMINERGIC SYSTEM; FEMALE; HEMISPHERE; HUMAN; HUMAN TISSUE; MALE; NEUROIMAGING; NUCLEUS ACCUMBENS; PRIORITY JOURNAL; PUTAMEN;

ADULT; ALCOHOLISM; AUTORADIOGRAPHY; CAUDATE NUCLEUS; CORPUS STRIATUM; DOMINANCE, CEREBRAL; FEMALE; HUMANS; MALE; MIDDLE AGED; NUCLEUS ACCUMBENS; PUTAMEN; RECEPTORS, DOPAMINE D1; RECEPTORS, DOPAMINE D2; REFERENCE VALUES; TETRABENAZINE; TRITIUM; VESICULAR MONOAMINE TRANSPORT PROTEINS;

EID: 43049153374     PISSN: 09254927     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pscychresns.2007.12.001     Document Type: Article

References (28)

1. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed, revised (1987), American Psychiatric Press, Washington, DC
2. Cloninger C.R. The psychobiological regulation of social cooperation. Nature Medicine 1 (1995) 623-624
3. Cohen J. A coefficient of agreement for nominal scales. Educational and psychological measurement 20 (1960) 37-46
4. 11C]tetrabenazine. Synapse 14 (1993) 128-131
5. Di Chiara G., and Imperato A. Drugs abused by humans preferentially increase synaptic dopamine concentrations in the mesolimbic system of freely moving rats. Proceedings of the National Academy of Sciences of the United States of America 85 (1988) 5274-5278
6. Frey K., Kilbourn M., and Robinson T. Reduced striatal vesicular monoamine transporters after neurotoxic but not after behaviorally-sensitizing doses of methamphetamine. European Journal of Pharmacology 334 (1997) 273-279
7. 11C]dihydrotetrabenazine and positron emission tomography. Annals of Neurology 44 (1998) 326-333
8. Landis J.R., and Koch G.G. The measurement of observer agreement for categorial data. Biometrics 33 (1977) 159-174
9. Little K.Y., Krolewski D.M., Zhang L., and Cassing B.J. Loss of striatal vesicular monoamine transporter protein (VMAT2) in human cocaine users. American Journal of Psychiatry 160 (2003) 47-55
10. Martinez D., Gil R., Slifstein M., Hwang D.R., Huang Y., Perez A., Kegeles L., Talbot P., Evans S., Krystal J., Laruelle M., and Abi-Dargham A. Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum. Biological Psychiatry 58 10 (2005) 779-786
11. Naudon L., Leroux-Nicollete I., and Costentin J. Short-term treatments with haloperidol or bromocriptine do not alter the density of the monoamine vesicular transporter in the substantia nigra. Neuroscience Letters 173 (1994) 1-4
12. Repo E., Kuikka J.T., Bergström K.A., Karhu J., Hiltunen J., and Tiihonen J. Dopamine transporter and D2-receptor density in late onset alcoholism. Psychopharmacology 147 (1999) 314-318
13. Schwartz K., Weizman A., and Rehavi M. Decreased platelet vesicular monoamine transporter density in habitual smokers. European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology 15 (2005) 235-238
14. Schwartz K., Iancu I., Stryjer R., Chelben J., Kotler M., Weizman A., and Rehavi M. Reduced platelet vesicular monoamine transporter density in smoking schizophrenia patients. European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology 15 (2005) 557-561
15. Schwartz K., Nachman R., Yossifoff M., Sapir R., Weizman A., and Rehavi M. Cocaine, but not amphetamine, short term treatment elevates the density of rat brain vesicular monoamine transporter 2. Journal of Neural Transmission 114 4 (2007) 427-430
16. Shapiro S.S., Wilk M.B., and Chen H.J. A comparative study of various tests for normality. Journal of the American Statistical Association 63 (1968) 1343-1372
17. Sossi V., Holden J.E., Topping G.J., Camborde M.L., Kornelsen R.A., McCormick S.E., Greene J., Studenov A.R., Ruth T.J., and Doudet D.J. In vivo measurement of density and affinity of the monoamine vesicular transport in a unilateral 6-hydroxydopamine rat model in PD. Journal of Cerebral Blood Flow and Metabolism 27 7 (2007) 1407-1415
18. Tiihonen J., Kuikka J., Bergström K., Hakola P., Karhu J., Ryynänen O.-P., and Föhr J. Altered striatal dopamine re-uptake site densities in habitually violent and non-violent alcoholics. Nature Medicine 1 (1995) 654-657
19. Tupala E., Hall H., Särkioja T., Räsänen P., and Tiihonen J. Dopamine transporter density in nucleus accumbens of type 1 alcoholics. Lancet 355 (2000) 380
20. Tupala E., Kuikka J.T., Hall H., Bergström K., Särkioja T., Räsänen P., Mantere T., Hiltunen J., Vepsäläinen J., and Tiihonen J. Measurement of the striatal dopamine transporter in type 1 alcoholics using human whole hemisphere autoradiography and fractal analysis. NeuroImage 14 (2001) 87-94
21. Tupala E., Hall H., Bergström K., Särkioja T., Räsänen P., Mantere T., Callaway J., Hiltunen J., and Tiihonen J. Dopamine D2/D3-receptor and transporter densities in nucleus accumbens and amygdala of type 1 and 2 alcoholics. Molecular Psychiatry 6 (2001) 261-267
22. Tupala E., Hall H., Bergström K., Mantere T., Räsänen P., Särkioja T., and Tiihonen J. Dopamine D2 receptors and transporters in type 1 and 2 alcoholics measured with whole hemisphere autoradiography. Human Brain Mapping 20 (2003) 91-102
23. Tupala E., Hall H., Mantere T., Räsänen P., Särkioja T., and Tiihonen J. Dopamine receptors and transporters in the brain reward circuits of type 1 and 2 alcoholics measured with whole hemisphere autoradiography. NeuroImage 19 (2003) 145-155
24. van der Borght T., Kilbourn M., Desmond T., Kuhl D., and Frey K. The vesicular monoamine transporter is not regulated by dopaminergic drug treatments. European Journal of Pharmacology 294 (1995) 577-583
25. Volkow N.D., Wang G.J., Fowler J.S., Logan J., Hitzemann R., Ding Y.S., Pappas M., Shea C., and Piscani K. Decreases in dopamine receptors but not in dopamine transporters in alcoholics. Alcoholism, Clinical and Experimental Research 20 9 (1996) 1594-1598
26. Yoder K.K., Constantinescu C.C., Kareken D.A., Normandin M.D., Cheng T.E., O'Connor S.J., and Morris E.D. Heterogeneous effects of alcohol on dopamine release in the striatum: a PET study. Alcoholism, Clinical and Experimental Research 31 6 (2007) 965-973
27. Zar J.H. Biostatistical Analysis. 2nd ed. (1984), Prentice-Hall Inc., Englewood Cliffs, NJ 310-317
28. Zucker M., Weizman A., Harel D., and Rehavi M. Changes in vesicular monoamine transporter (VMAT2) and synaptophysin in rat substantia nigra and prefrontal cortex induced by psychotropic drugs. Neuropsychobiology 44 4 (2001) 187-191