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Volumn 4, Issue 4, 2008, Pages

A novel secretion pathway of Salmonella enterica acts as an antivirulence modulator during salmonellosis

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CARRIER PROTEIN; INTIMIN; INVASIN; OUTER MEMBRANE PROTEIN; PROTEIN ZIRS; PROTEIN ZIRT; ZINC; BACTERIAL RNA; BETA GALACTOSIDASE; DNA BINDING PROTEIN; SSEK1 PROTEIN, SALMONELLA ENTERICA; SSEK2 PROTEIN, SALMONELLA ENTERICA; VIRULENCE FACTOR; ZINC DERIVATIVE;

EID: 43049144649     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1000036     Document Type: Article
Times cited : (44)

References (59)
  • 1
    • 0036128837 scopus 로고    scopus 로고
    • Pathogenicity islands and host adaptation of Salmonella serovars
    • Kingsley RA, Baumler AJ (2002) Pathogenicity islands and host adaptation of Salmonella serovars. Curr Top Microbiol Immunol 264: 67-87.
    • (2002) Curr Top Microbiol Immunol , vol.264 , pp. 67-87
    • Kingsley, R.A.1    Baumler, A.J.2
  • 5
    • 0034541135 scopus 로고    scopus 로고
    • Autotransporter proteins, evolution and redefining protein secretion
    • Henderson IR, Cappello R, Nataro JP (2000) Autotransporter proteins, evolution and redefining protein secretion. Trends Microbiol 8: 529-532.
    • (2000) Trends Microbiol , vol.8 , pp. 529-532
    • Henderson, I.R.1    Cappello, R.2    Nataro, J.P.3
  • 7
    • 33747120540 scopus 로고    scopus 로고
    • Surface display of proteins by gram-negative bacterial autotransporters
    • Rutherford N, Mourez M (2006) Surface display of proteins by gram-negative bacterial autotransporters. Microb Cell Fact 5: 22.
    • (2006) Microb Cell Fact , vol.5 , pp. 22
    • Rutherford, N.1    Mourez, M.2
  • 8
    • 8844235655 scopus 로고    scopus 로고
    • Protein secretion through autotransporter and two-partner pathways
    • Jacob-Dubuisson F, Fernandez R, Coutte L (2004) Protein secretion through autotransporter and two-partner pathways. Biochim Biophys Acta 1694: 235-257.
    • (2004) Biochim Biophys Acta , vol.1694 , pp. 235-257
    • Jacob-Dubuisson, F.1    Fernandez, R.2    Coutte, L.3
  • 9
    • 0035035580 scopus 로고    scopus 로고
    • Two-partner secretion in Gram-negative bacteria: A thrifty, specific pathway for large virulence proteins
    • Jacob-Dubuisson F, Locht C, Antoine R (2001) Two-partner secretion in Gram-negative bacteria: a thrifty, specific pathway for large virulence proteins. Mol Microbiol 40: 306-313.
    • (2001) Mol Microbiol , vol.40 , pp. 306-313
    • Jacob-Dubuisson, F.1    Locht, C.2    Antoine, R.3
  • 10
    • 34548128883 scopus 로고    scopus 로고
    • Structure of the membrane protein FhaC: A member of the Omp85-TpsB transporter superfamily
    • Clantin B, Delattre AS, Rucktooa P, Saint N, Meli AC, et al. (2007) Structure of the membrane protein FhaC: a member of the Omp85-TpsB transporter superfamily. Science 317: 957-961.
    • (2007) Science , vol.317 , pp. 957-961
    • Clantin, B.1    Delattre, A.S.2    Rucktooa, P.3    Saint, N.4    Meli, A.C.5
  • 11
    • 1642493657 scopus 로고    scopus 로고
    • Adhesins and invasins of pathogenic bacteria: A structural view
    • Niemann HH, Schubert WD, Heinz DW (2004) Adhesins and invasins of pathogenic bacteria: a structural view. Microbes Infect 6: 101-112.
    • (2004) Microbes Infect , vol.6 , pp. 101-112
    • Niemann, H.H.1    Schubert, W.D.2    Heinz, D.W.3
  • 12
    • 1842861589 scopus 로고    scopus 로고
    • Structural biology of bacterial pathogenesis
    • Remaut H, Waksman G (2004) Structural biology of bacterial pathogenesis. Curr Opin Struct Biol 14: 161-170.
    • (2004) Curr Opin Struct Biol , vol.14 , pp. 161-170
    • Remaut, H.1    Waksman, G.2
  • 13
    • 9344245722 scopus 로고    scopus 로고
    • Autotransporter and two-partner secretion: Delivery of large-size virulence factors by gram-negative bacterial pathogens
    • Newman CL, Stathopoulos C (2004) Autotransporter and two-partner secretion: delivery of large-size virulence factors by gram-negative bacterial pathogens. Crit Rev Microbiol 30: 275-286.
    • (2004) Crit Rev Microbiol , vol.30 , pp. 275-286
    • Newman, C.L.1    Stathopoulos, C.2
  • 14
    • 0346334430 scopus 로고    scopus 로고
    • Self-association of EPEC intimin mediated by the beta-barrel-containing anchor domain: A role in clustering of the Tir receptor
    • Touze T, Hayward RD, Eswaran J, Leong JM, Koronakis V (2004) Self-association of EPEC intimin mediated by the beta-barrel-containing anchor domain: a role in clustering of the Tir receptor. Mol Microbiol 51: 73-87.
    • (2004) Mol Microbiol , vol.51 , pp. 73-87
    • Touze, T.1    Hayward, R.D.2    Eswaran, J.3    Leong, J.M.4    Koronakis, V.5
  • 15
    • 27144522274 scopus 로고    scopus 로고
    • Convergent evolution as a mechanism for pathogenic adaptation
    • Sikora S, Strongin A, Godzik A (2005) Convergent evolution as a mechanism for pathogenic adaptation. Trends Microbiol 13: 522-527.
    • (2005) Trends Microbiol , vol.13 , pp. 522-527
    • Sikora, S.1    Strongin, A.2    Godzik, A.3
  • 16
    • 31844447028 scopus 로고    scopus 로고
    • Adaptation of Legionella pneumophila to the host environment: Role of protein secretion, effectors and eukaryotic-like proteins
    • Bruggemann H, Cazalet C, Buchrieser C (2006) Adaptation of Legionella pneumophila to the host environment: role of protein secretion, effectors and eukaryotic-like proteins. Curr Opin Microbiol 9: 86-94.
    • (2006) Curr Opin Microbiol , vol.9 , pp. 86-94
    • Bruggemann, H.1    Cazalet, C.2    Buchrieser, C.3
  • 17
    • 0035950182 scopus 로고    scopus 로고
    • Complete genome sequence of Salmonella enterica serovar Typhimurium LT2
    • McClelland M, Sanderson KE, Spieth J, Clifton SW, Latreille P, et al. (2001) Complete genome sequence of Salmonella enterica serovar Typhimurium LT2. Nature 413: 852-856.
    • (2001) Nature , vol.413 , pp. 852-856
    • McClelland, M.1    Sanderson, K.E.2    Spieth, J.3    Clifton, S.W.4    Latreille, P.5
  • 18
    • 0342378138 scopus 로고    scopus 로고
    • The record of horizontal gene transfer in Salmonella
    • Baumler AJ (1997) The record of horizontal gene transfer in Salmonella. Trends Microbiol 5: 318-322.
    • (1997) Trends Microbiol , vol.5 , pp. 318-322
    • Baumler, A.J.1
  • 19
    • 0033768412 scopus 로고    scopus 로고
    • Bacterial virulence gene regulation: An evolutionary perspective
    • Cotter PA, DiRita VJ (2000) Bacterial virulence gene regulation: an evolutionary perspective. Annu Rev Microbiol 54: 519-565.
    • (2000) Annu Rev Microbiol , vol.54 , pp. 519-565
    • Cotter, P.A.1    DiRita, V.J.2
  • 21
    • 0033943049 scopus 로고    scopus 로고
    • Escherichia coli translocase: The unravelling of a molecular machine
    • Manting EH, Driessen AJ (2000) Escherichia coli translocase: the unravelling of a molecular machine. Mol Microbiol 37: 226-238.
    • (2000) Mol Microbiol , vol.37 , pp. 226-238
    • Manting, E.H.1    Driessen, A.J.2
  • 22
    • 0029043218 scopus 로고
    • Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secA
    • Huie JL, Silhavy TJ (1995) Suppression of signal sequence defects and azide resistance in Escherichia coli commonly result from the same mutations in secA. J Bacteriol 177: 3518-3526.
    • (1995) J Bacteriol , vol.177 , pp. 3518-3526
    • Huie, J.L.1    Silhavy, T.J.2
  • 23
    • 0025338413 scopus 로고
    • The proton-translocating ATPase of Escherichia coli
    • Senior AE (1990) The proton-translocating ATPase of Escherichia coli. Annu Rev Biophys Biophys Chem 19: 7-41.
    • (1990) Annu Rev Biophys Biophys Chem , vol.19 , pp. 7-41
    • Senior, A.E.1
  • 24
    • 15844431346 scopus 로고    scopus 로고
    • PSORTb v.2.0: Expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis
    • Gardy JL, Laird MR, Chen F, Rey S, Walsh CJ, et al. (2005) PSORTb v.2.0: expanded prediction of bacterial protein subcellular localization and insights gained from comparative proteome analysis. Bioinformatics 21: 617-623.
    • (2005) Bioinformatics , vol.21 , pp. 617-623
    • Gardy, J.L.1    Laird, M.R.2    Chen, F.3    Rey, S.4    Walsh, C.J.5
  • 25
    • 1842688091 scopus 로고    scopus 로고
    • Neural network-based prediction of transmembrane beta-strand segments in outer membrane proteins
    • Gromiha MM, Ahmad S, Suwa M (2004) Neural network-based prediction of transmembrane beta-strand segments in outer membrane proteins. J Comput Chem 25: 762-767.
    • (2004) J Comput Chem , vol.25 , pp. 762-767
    • Gromiha, M.M.1    Ahmad, S.2    Suwa, M.3
  • 26
    • 0021104781 scopus 로고
    • Cloning and molecular characterization of the ompA gene from Salmonella typhimurium
    • Freudl R, Cole ST (1983) Cloning and molecular characterization of the ompA gene from Salmonella typhimurium. Eur J Biochem 134: 497-502.
    • (1983) Eur J Biochem , vol.134 , pp. 497-502
    • Freudl, R.1    Cole, S.T.2
  • 27
    • 0033981085 scopus 로고    scopus 로고
    • Structure and function of the F(o) complex of the ATP synthase from Escherichia coli
    • Altendorf K, Stalz W, Greie J, Deckers-Hebestreit G (2000) Structure and function of the F(o) complex of the ATP synthase from Escherichia coli. J Exp Biol 203: 19-28.
    • (2000) J Exp Biol , vol.203 , pp. 19-28
    • Altendorf, K.1    Stalz, W.2    Greie, J.3    Deckers-Hebestreit, G.4
  • 28
    • 0015651967 scopus 로고
    • Outer membrane proteins of Escherichia coli. I. Effect of preparative conditions on the migration of protein in polyacrylamide gels
    • Schnaitman CA (1973) Outer membrane proteins of Escherichia coli. I. Effect of preparative conditions on the migration of protein in polyacrylamide gels. Arch Biochem Biophys 157: 541-552.
    • (1973) Arch Biochem Biophys , vol.157 , pp. 541-552
    • Schnaitman, C.A.1
  • 29
    • 3543068251 scopus 로고    scopus 로고
    • Regulog analysis: Detection of conserved regulatory networks across bacteria: application to Staphylococcus aureus
    • Alkema WB, Lenhard B, Wasserman WW (2004) Regulog analysis: detection of conserved regulatory networks across bacteria: application to Staphylococcus aureus. Genome Res 14: 1362-1373.
    • (2004) Genome Res , vol.14 , pp. 1362-1373
    • Alkema, W.B.1    Lenhard, B.2    Wasserman, W.W.3
  • 31
    • 0035968001 scopus 로고    scopus 로고
    • Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis
    • Outten CE, O'Halloran TV (2001) Femtomolar sensitivity of metalloregulatory proteins controlling zinc homeostasis. Science 292: 2488-2492.
    • (2001) Science , vol.292 , pp. 2488-2492
    • Outten, C.E.1    O'Halloran, T.V.2
  • 32
    • 0035671378 scopus 로고    scopus 로고
    • Use of mixed infections with Salmonella strains to study virulence genes and their interactions in vivo
    • Beuzon CR, Holden DW (2001) Use of mixed infections with Salmonella strains to study virulence genes and their interactions in vivo. Microbes Infect 3: 1345-1352.
    • (2001) Microbes Infect , vol.3 , pp. 1345-1352
    • Beuzon, C.R.1    Holden, D.W.2
  • 33
    • 0034848892 scopus 로고    scopus 로고
    • Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo
    • Salcedo SP, Noursadeghi M, Cohen J, Holden DW (2001) Intracellular replication of Salmonella typhimurium strains in specific subsets of splenic macrophages in vivo. Cell Microbiol 3: 587-597.
    • (2001) Cell Microbiol , vol.3 , pp. 587-597
    • Salcedo, S.P.1    Noursadeghi, M.2    Cohen, J.3    Holden, D.W.4
  • 34
    • 0033822695 scopus 로고    scopus 로고
    • Use of confocal microscopy to detect Salmonella typhimurium within host cells associated with Spv-mediated intracellular proliferation
    • Matsui H, Eguchi M, Kikuchi Y (2000) Use of confocal microscopy to detect Salmonella typhimurium within host cells associated with Spv-mediated intracellular proliferation. Microb Pathog 29: 53-59.
    • (2000) Microb Pathog , vol.29 , pp. 53-59
    • Matsui, H.1    Eguchi, M.2    Kikuchi, Y.3
  • 35
    • 0030807629 scopus 로고    scopus 로고
    • Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo
    • Richter-Dahlfors A, Buchan AM, Finlay BB (1997) Murine salmonellosis studied by confocal microscopy: Salmonella typhimurium resides intracellularly inside macrophages and exerts a cytotoxic effect on phagocytes in vivo. J Exp Med 186: 569-580.
    • (1997) J Exp Med , vol.186 , pp. 569-580
    • Richter-Dahlfors, A.1    Buchan, A.M.2    Finlay, B.B.3
  • 36
    • 0033962110 scopus 로고    scopus 로고
    • Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport
    • Gruenheid S, Gros P (2000) Genetic susceptibility to intracellular infections: Nramp1, macrophage function and divalent cations transport. Curr Opin Microbiol 3: 43-48.
    • (2000) Curr Opin Microbiol , vol.3 , pp. 43-48
    • Gruenheid, S.1    Gros, P.2
  • 37
    • 0041530033 scopus 로고    scopus 로고
    • Genomic profiling of iron-responsive genes in Salmonella enterica serovar typhimurium by high-throughput screening of a random promoter library
    • Bjarnason J, Southward CM, Surette MG (2003) Genomic profiling of iron-responsive genes in Salmonella enterica serovar typhimurium by high-throughput screening of a random promoter library. J Bacteriol 185: 4973-4982.
    • (2003) J Bacteriol , vol.185 , pp. 4973-4982
    • Bjarnason, J.1    Southward, C.M.2    Surette, M.G.3
  • 38
    • 0034757560 scopus 로고    scopus 로고
    • Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins
    • Kajava AV, Cheng N, Cleaver R, Kessel M, Simon MN, et al. (2001) Beta-helix model for the filamentous haemagglutinin adhesin of Bordetella pertussis and related bacterial secretory proteins. Mol Microbiol 42: 279-292.
    • (2001) Mol Microbiol , vol.42 , pp. 279-292
    • Kajava, A.V.1    Cheng, N.2    Cleaver, R.3    Kessel, M.4    Simon, M.N.5
  • 39
    • 33748496461 scopus 로고    scopus 로고
    • Secretion signal of the filamentous haemagglutinin, a model two-partner secretion substrate
    • Hodak H, Clantin B, Willery E, Villeret V, Locht C, et al. (2006) Secretion signal of the filamentous haemagglutinin, a model two-partner secretion substrate. Mol Microbiol 61: 368-382.
    • (2006) Mol Microbiol , vol.61 , pp. 368-382
    • Hodak, H.1    Clantin, B.2    Willery, E.3    Villeret, V.4    Locht, C.5
  • 40
    • 1942437434 scopus 로고    scopus 로고
    • The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway
    • Clantin B, Hodak H, Willery E, Locht C, Jacob-Dubuisson F, et al. (2004) The crystal structure of filamentous hemagglutinin secretion domain and its implications for the two-partner secretion pathway. Proc Natl Acad Sci U S A 101: 6194-6199.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 6194-6199
    • Clantin, B.1    Hodak, H.2    Willery, E.3    Locht, C.4    Jacob-Dubuisson, F.5
  • 42
    • 0035852690 scopus 로고    scopus 로고
    • The insect endosymbiont Sodalis glossinidius utilizes a type III secretion system for cell invasion
    • Dale C, Young SA, Haydon DT, Welburn SC (2001) The insect endosymbiont Sodalis glossinidius utilizes a type III secretion system for cell invasion. Proc Natl Acad Sci U S A 98: 1883-1888.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 1883-1888
    • Dale, C.1    Young, S.A.2    Haydon, D.T.3    Welburn, S.C.4
  • 43
    • 0035188434 scopus 로고    scopus 로고
    • Salmonella interactions with host cells: Type III secretion at work
    • Galan JE (2001) Salmonella interactions with host cells: type III secretion at work. Annu Rev Cell Dev Biol 17: 53-86.
    • (2001) Annu Rev Cell Dev Biol , vol.17 , pp. 53-86
    • Galan, J.E.1
  • 45
    • 0036040618 scopus 로고    scopus 로고
    • Conflicting needs for a Salmonella hypervirulence gene in host and non-host environments
    • Mouslim C, Hilbert F, Huang H, Groisman EA (2002) Conflicting needs for a Salmonella hypervirulence gene in host and non-host environments. Mol Microbiol 45: 1019-1027.
    • (2002) Mol Microbiol , vol.45 , pp. 1019-1027
    • Mouslim, C.1    Hilbert, F.2    Huang, H.3    Groisman, E.A.4
  • 46
    • 21544479117 scopus 로고    scopus 로고
    • sciS, an icmF homolog in Salmonella enterica serovar Typhimurium, limits intracellular replication and decreases virulence
    • Parsons DA, Heffron F (2005) sciS, an icmF homolog in Salmonella enterica serovar Typhimurium, limits intracellular replication and decreases virulence. Infect Immun 73: 4338-4345.
    • (2005) Infect Immun , vol.73 , pp. 4338-4345
    • Parsons, D.A.1    Heffron, F.2
  • 47
    • 0035152757 scopus 로고    scopus 로고
    • Characterization of grvA, an antivirulence gene on the gifsy-2 phage in Salmonella enterica serovar typhimurium
    • Ho TD, Slauch JM (2001) Characterization of grvA, an antivirulence gene on the gifsy-2 phage in Salmonella enterica serovar typhimurium. J Bacteriol 183: 611-620.
    • (2001) J Bacteriol , vol.183 , pp. 611-620
    • Ho, T.D.1    Slauch, J.M.2
  • 49
    • 0032579193 scopus 로고    scopus 로고
    • Improved allelic exchange vectors and their use to analyze 987P fimbria gene expression
    • Edwards RA, Keller LH, Schifferli DM (1998) Improved allelic exchange vectors and their use to analyze 987P fimbria gene expression. Gene 207: 149-157.
    • (1998) Gene , vol.207 , pp. 149-157
    • Edwards, R.A.1    Keller, L.H.2    Schifferli, D.M.3
  • 50
    • 0029888153 scopus 로고    scopus 로고
    • Generation of unmarked directed mutations in mycobacteria, using sucrose counter-selectable suicide vectors
    • Pelicic V, Reyrat JM, Gicquel B (1996) Generation of unmarked directed mutations in mycobacteria, using sucrose counter-selectable suicide vectors. Mol Microbiol 20: 919-925.
    • (1996) Mol Microbiol , vol.20 , pp. 919-925
    • Pelicic, V.1    Reyrat, J.M.2    Gicquel, B.3
  • 51
    • 0023892552 scopus 로고
    • A novel suicide vector and its use in construction of insertion mutations: Osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR
    • Miller VL, Mekalanos JJ (1988) A novel suicide vector and its use in construction of insertion mutations: osmoregulation of outer membrane proteins and virulence determinants in Vibrio cholerae requires toxR. J Bacteriol 170: 2575-2583.
    • (1988) J Bacteriol , vol.170 , pp. 2575-2583
    • Miller, V.L.1    Mekalanos, J.J.2
  • 52
  • 53
    • 0029092312 scopus 로고
    • The Ity/Lsh/Bcg locus: Natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene
    • Vidal S, Tremblay ML, Govoni G, Gauthier S, Sebastiani G, et al. (1995) The Ity/Lsh/Bcg locus: natural resistance to infection with intracellular parasites is abrogated by disruption of the Nramp1 gene. J Exp Med 182: 655-666.
    • (1995) J Exp Med , vol.182 , pp. 655-666
    • Vidal, S.1    Tremblay, M.L.2    Govoni, G.3    Gauthier, S.4    Sebastiani, G.5
  • 54
    • 33748131674 scopus 로고    scopus 로고
    • The temperature-sensing protein TlpA is repressed by PhoP and dispensable for virulence of Salmonella enterica serovar Typhimurium in mice
    • Gal-Mor O, Valdez Y, Finlay BB (2006) The temperature-sensing protein TlpA is repressed by PhoP and dispensable for virulence of Salmonella enterica serovar Typhimurium in mice. Microbes Infect 8: 2154-2162.
    • (2006) Microbes Infect , vol.8 , pp. 2154-2162
    • Gal-Mor, O.1    Valdez, Y.2    Finlay, B.B.3
  • 55
    • 28444439542 scopus 로고    scopus 로고
    • Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid
    • Coombes BK, Wickham ME, Lowden MJ, Brown NF, Finlay BB (2005) Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid. Proc Natl Acad Sci U S A 102: 17460-17465.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 17460-17465
    • Coombes, B.K.1    Wickham, M.E.2    Lowden, M.J.3    Brown, N.F.4    Finlay, B.B.5
  • 56
    • 30744432161 scopus 로고    scopus 로고
    • Coordinated regulation of two independent cell-cell signaling systems and swarmer differentiation in Salmonella enterica serovar Typhimurium
    • Kim W, Surette MG (2006) Coordinated regulation of two independent cell-cell signaling systems and swarmer differentiation in Salmonella enterica serovar Typhimurium. J Bacteriol 188: 431-440.
    • (2006) J Bacteriol , vol.188 , pp. 431-440
    • Kim, W.1    Surette, M.G.2
  • 58
    • 0018959055 scopus 로고
    • In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals
    • Casadaban MJ, Chou J, Cohen SN (1980) In vitro gene fusions that join an enzymatically active beta-galactosidase segment to amino-terminal fragments of exogenous proteins: Escherichia coli plasmid vectors for the detection and cloning of translational initiation signals. J Bacteriol 143: 971-980.
    • (1980) J Bacteriol , vol.143 , pp. 971-980
    • Casadaban, M.J.1    Chou, J.2    Cohen, S.N.3
  • 59
    • 0025782890 scopus 로고
    • Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli
    • Wang RF, Kushner SR (1991) Construction of versatile low-copy-number vectors for cloning, sequencing and gene expression in Escherichia coli. Gene 100: 195-199.
    • (1991) Gene , vol.100 , pp. 195-199
    • Wang, R.F.1    Kushner, S.R.2


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