Development of breakpoints of cephems for intraabdominal infections based on pharmacokinetics and pharmacodynamics in the peritoneal fluid of patients

Journal of Infection and Chemotherapy

Volumn 14, Issue 2, 2008, Pages 141-146

  Ikawa, Kazuro ^a   Morikawa, Norifumi ^a   Ikeda, Kayo ^a   Ohge, Hiroki ^a   Sueda, Taijiro ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

Author keywords

Dosing regimen; Monte Carlo simulation; Peritoneal fluid; Pharmacodynamics; Population pharmacokinetics

Indexed keywords

CEFEPIME; CEFOTIAM; CEFOZOPRAN; FLOMOXEF;

ABDOMINAL INFECTION; ABDOMINAL SURGERY; ADULT; ANTIBIOTIC SENSITIVITY; ANTIBIOTIC THERAPY; ARTICLE; BACTERICIDAL ACTIVITY; BACTERIOSTASIS; BLOOD SAMPLING; CLINICAL ARTICLE; DRUG BLOOD LEVEL; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; FEMALE; HUMAN; KLEBSIELLA; MALE; MINIMUM INHIBITORY CONCENTRATION; MONTE CARLO METHOD; PERITONEAL FLUID; STATISTICAL MODEL; SURGICAL PATIENT; TREATMENT OUTCOME; VENOUS BLOOD;

EID: 43049144265     PISSN: 1341321X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10156-008-0598-z     Document Type: Article

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