Labetalol facilitates GABAergic transmission to rat periaqueductal gray neurons via antagonizing β1-adrenergic receptors - A possible mechanism underlying labetalol-induced analgesia

Brain Research

Volumn 1198, Issue , 2008, Pages 34-43

  Xiao, Cheng ^a   Zhou, Chunyi ^a   Atlas, Glen ^a   Delphin, Ellise ^a   Ye, Jiang Hong ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Analgesia; Brain slices; Firing; GABAergic transmission; IPSCs; Labetalol; Periaqueductal gray; Rat; 1 adrenergic receptors

Indexed keywords

4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 1 ADRENERGIC RECEPTOR; BETA 1 ADRENERGIC RECEPTOR BLOCKING AGENT; BETA 2 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; BICUCULLINE; LABETALOL; METOPROLOL; OPIATE;

ANALGESIA; ANALGESIC ACTIVITY; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; GABAERGIC TRANSMISSION; HYPERPOLARIZATION; IN VIVO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; INTERNEURON; NONHUMAN; PATCH CLAMP; PERIAQUEDUCTAL GRAY MATTER; PRESYNAPTIC MEMBRANE; PRIORITY JOURNAL; RAT; RECEPTOR DOWN REGULATION;

RATTUS;

EID: 43049139474     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2008.01.023     Document Type: Article

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