Trivalent, Gal/GalNAc-containing ligands designed for the asialoglycoprotein receptor

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 9, 2008, Pages 5216-5231

  Khorev, Oleg ^a   Stokmaier, Daniela ^a   Schwardt, Oliver ^a   Cutting, Brian ^a   Ernst, Beat ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

Author keywords

Asialoglycoprotein receptor (ASGP R); Drug delivery; Flow cytometry; Fluorescence microscopy; Fluorescent probes

Indexed keywords

4 (BENZYLOXYCARBONYLAMINO) N [[TRIS(BETA DEXTRO GALACTOPYRANOSYLOXY)METHYL]METHYL]BUTYRAMIDE; 4 (BENZYLOXYCARBONYLAMINO) N [[TRIS(HYDROXYMETHYL)]METHYL]BUTYRAMIDE; 4 AMINO N [[TRIS(BETA DEXTRO GALACTOPYRANOSYLOXY)METHYL]METHYL]BUTYRAMIDE; ASIALOGLYCOPROTEIN RECEPTOR; LIGAND; N [[TRIS(2,3,4,6 TETRA O BENZOYL BETA DEXTRO GALACTOPYRANOSYLOXY)METHYL]METHYL](4 BENZYLOXYCARBONYLAMINO)BUTYRAMIDE; N [TRIS[13 (2 ACETAMIDO 3,4,6 O ACETYL BETA DEXTRO GALACTOPYRANOSYLOXY) 2,6,10 TRIOXATRIDECYL]METHYL](4 BENZYLOXYCARBONYLAMINO)BUTYRAMIDE; N [TRIS[13 (2 ACETAMIDO BETA DEXTRO GALACTOPYRANOSYLOXY) 2,6,10 TRIOXATRIDECYL]METHYL] 4 (BENZYLOXYCARBONYLAMINO)BUTYRAMIDE; N [TRIS[13 (2 ACETAMIDO BETA DEXTRO GALACTOPYRANOSYLOXY) 2,6,10 TRIOXATRIDECYL]METHYL] 4 AMINOBUTYRAMIDE; N [TRIS[13 [3,4,6 TRI O ACETYL 2 (2,2,2 TRICHLOTOETHOXYCARBONYLAMINO) BETA DEXTRO GALACTOPYRANOSYLOXY] 2,6,10 TRIOXATRIDECYL]METHYL](4 BENZYLOXYCARBONYLAMINO)BUTYRAMIDE;

ARTICLE; CONTROLLED STUDY; DRUG BINDING SITE; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; DRUG SYNTHESIS; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; INTERNALIZATION; LIVER CELL; LIVER PARENCHYMA;

ANTIGENS, TUMOR-ASSOCIATED, CARBOHYDRATE; ASIALOGLYCOPROTEIN RECEPTOR; BINDING SITES; CELL LINE, TUMOR; DRUG DESIGN; FLOW CYTOMETRY; FLUORESCENCE; HUMANS; LIGANDS; LIVER; MICROSCOPY, FLUORESCENCE; MOLECULAR STRUCTURE; PROPYLENE GLYCOLS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 43049125473     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.03.017     Document Type: Article

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