Pore structure engineering for carbon foams as possible bone implant material

Journal of Biomedical Materials Research - Part A

Volumn 85, Issue 3, 2008, Pages 588-596

  Turgut, Gursel ^a   Eksilioglu, Ayhan ^b   Gencay, Nagehan ^b   Gonen, Emre ^a   Hekim, Nezih ^c   Yardim, M F ^b   Sakiz, Damlanur ^a   Ekinci, Ekrem ^b  

^a Sisli Etfal Research Hospital   (Turkey)

^b ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

^c Genkord   (Turkey)

Author keywords

Biocompatibility; Bone implant; Carbon foam; Mesophase pitch; Porosity

Indexed keywords

BIOCOMPATIBILITY; BONE; CARBON; CYTOTOXICITY; IMPLANTS (SURGICAL); PORE STRUCTURE; SOLVENTS; TOLUENE; XYLENE;

BONE IMPLANT; CARBON FOAMS; MESOPHASE PITCH;

FOAMS;

CARBON; GRAPHITE; TOLUENE; XYLENE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOCOMPATIBILITY; BIOMEDICAL ENGINEERING; COMPARATIVE STUDY; COMPRESSIVE STRENGTH; CYTOTOXICITY; DENSITY; FOAM; FOLLOW UP; HISTOLOGY; IMPLANT; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; POROSITY; POSTOPERATIVE PERIOD; POWDER; PRESSURE; RAT; TEMPERATURE;

ANIMALS; BIOCOMPATIBLE MATERIALS; BONE SUBSTITUTES; CARBON; POROSITY; RATS; RATS, SPRAGUE-DAWLEY; TISSUE ENGINEERING;

EID: 43049120603     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31489     Document Type: Article

References (20)

1. Langer R, Vacanti JP. Tissue engineering. Science 1993;260:873-1013.
2. Sachlos E, Czernuszka JT. Making tissue engineering scaffolds work. Review on the application of solid freeform fabrication technology to the production of tissue engineering scaffolds. Eur Cells Mater 2003;5:29-40.
3. Yang S, Leong KF, Du Z, Chua CK. The design of scaffolds for use in tissue engineering. I. Traditional factors. Tissue Eng 2001;7:679-689.
4. Cima LG, Cima MJ. Tissue regeneration matrices by solid free form fabrication techniques. US Pat 5,518,680, 1996.
5. Peters MC, Mooney DJ. Synthetic extracellular matrices for cell transplantation. Mater Sci Forum 1997;250:43-52.
6. O'Brien FJ, Harley BA, Yannas IV, Gibson LJ. The effect of pore size on cell adhesion in collagen-GAG scaffolds. Biomaterials 2005;26:433-441.
7. Katoh K, Tanabe T, Yamauchi K. Novel approach to fabricate keratin sponge scaffolds with controlled pore size and porosity. Biomaterials 2004;25:4255-4262.
8. Klawitter JJ, Bagwell JG, Weinstein AM, Sauer BW. An evaluation of bone growth into porous high density polyethylene. J Biomed Mater Res 1975;10:311-323.
9. Klawitter JJ, Hulbert SFJ. Application of porous ceramics for the attachment of load bearing orthopedic applications. Biomed Mater Res Symp 1971;2:161-167.
10. Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA. Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes. J Biomed Mater Res A 2004;68:187-200.
11. Li S, de Wijn JR, Li J, Layrolle P, de Groot K. Macroporous biphasic calcium phosphate scaffold with high permeability/porosity ratio. Tissue Eng 2003;9:535-548.
12. Hulbert SF, Young FA, Mathews RS, Klawitter JJ, Talbert CD, Stelling FH. Potential of ceramic materials as permanently implantable skeletal prostheses. J Biomed Mater Res 1970;4:433-456.
13. Itala AI, Ylanen HO, Ekholm C, Karlsson KH, Aro HT. Pore diameter of more than 100 μM is not requisite for bone ingrowth in rabbits. J Biomed Mater Res Appl Biomater 2001;58:679-683.
14. http://www.ms.ornl.gov/researchgroups/CMT/FOAM/foams.htm, July 21, 2005.
15. Klett JW. 2000. Process for making carbon foam. US Pat 6,033,506, 2000.
16. Eksilioglu A, Gencay N, Yardim MF, Ekinci E. Mesophase AR pitch derived carbon foam: Effect of temperature, pressure and pressure release time. J Mater Sci 2006;41:2743-2748.
17. Klett JW, Hardy R, Romine E, Walls C, Burchell T. Carbon, high-thermal-conductivity, mesophase-pitch-derived carbon foams: Effect of precursor on structure and properties. Carbon 2000;38:953-973.
18. Klett J. Method for extruding pitch based foam. US Pat 6,344,159, 2002.
19. Eksilioglu A.Effect of temperature, solvent type and additives on the properties of mesophase pitch based carbon foam. M.S. Thesis, Department of Chemical Engineering, Istanbul Technical University, Istanbul, 2003.
20. Bonzom A, Crepaux AP, Moutars AEJ. Process for preparing pitch foams and products so produced. US Pat 4,276,246, 1981.