Characterization of Cu2+-binding modes in the prion protein by visible circular dichroism and multivariate curve resolution

Analytical Biochemistry

Volumn 377, Issue 2, 2008, Pages 223-233

  Pollock, J B ^a   Cutler, P J ^a   Kenney, J M ^a   Gemperline, P J ^a   Burns, C S ^a  

^a EAST CAROLINA UNIVERSITY   (United States)

Author keywords

Alternating least squares (ALS); Copper binding; Multivariate curve resolution (MCR); Prion protein (PrP); Self modeling curve resolution (SMCR); Visible circular dichroism (CD)

Indexed keywords

BINDING ENERGY; BIOCHEMISTRY; DICHROISM; LEAST SQUARES APPROXIMATIONS; METAL IONS; PROTEINS; TITRATION;

ALTERNATING LEAST SQUARES; COPPER BINDING; MULTIVARIATE CURVE RESOLUTION; PRION PROTEIN; SELF-MODELING CURVE RESOLUTION; VISIBLE CIRCULAR DICHROISM (CD);

COPPER COMPOUNDS;

CUPRIC ION; PRION PROTEIN; COPPER; PEPTIDE;

ANALYSIS; ARTICLE; BIOCHEMISTRY; CHEMICAL ANALYSIS; CONCENTRATION (PARAMETERS); MATHEMATICAL VARIABLE; METAL BINDING; PRIORITY JOURNAL; SPECTRUM; TITRIMETRY; AMINO ACID SEQUENCE; ANALYSIS OF VARIANCE; ANIMAL; BINDING SITE; CHEMISTRY; CIRCULAR DICHROISM; METABOLISM; METHODOLOGY; MOLECULAR GENETICS; PRION; REGRESSION ANALYSIS;

AMINO ACID SEQUENCE; ANALYSIS OF VARIANCE; ANIMALS; BINDING SITES; CIRCULAR DICHROISM; COPPER; LEAST-SQUARES ANALYSIS; MOLECULAR SEQUENCE DATA; PEPTIDES; PRIONS; TITRIMETRY;

EID: 43049119961     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2008.03.008     Document Type: Article

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