An Entirely Cell-Based System to Generate Single-Chain Antibodies against Cell Surface Receptors

Journal of Molecular Biology

Volumn 379, Issue 2, 2008, Pages 261-272

  Lipes, Barbara D ^a   Chen, Yu Hsun ^a   Ma, Hongzheng ^a   Staats, Herman F ^a   Kenan, Daniel J ^a   Gunn, Michael Dee ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

antibody; cell surface antigen; flow cytometry; phage displayed antibody; toll like receptor

Indexed keywords

ANTIBODY; CELL SURFACE RECEPTOR; RECOMBINANT PROTEIN; TOLL LIKE RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCTION; ARTICLE; BACTERIOPHAGE; CELL SURFACE; CONTROLLED STUDY; EMBRYO; EXPRESSION VECTOR; GENE LIBRARY; GENETIC TRANSFECTION; HIGH THROUGHPUT SCREENING; HUMAN; HUMAN CELL; IMMUNIZATION; INNATE IMMUNITY; INSECT CELL; MICROORGANISM; MOLECULAR CLONING; MOLECULE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RISK;

HEXAPODA; MUS;

EID: 43049114512     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2008.03.072     Document Type: Article

References (26)

1. G. Kohler C. Milstein Continuous cultures of fused cells secreting antibody of predefined specificity Nature 256 1975 495 497
2. D.P. McCafferty A.D. Griffiths G. Winter D.J. Chiswell Phage antibodies: filamentous phage displaying antibody variable fragments Nature 348 1990 552 554
3. N.J. Gay M. Gangloff A.N. Weber Toll-like receptors as molecular switches Nat. Rev. Immunol. 6 2006 69 698
4. H. Kanzler F.J. Barrat E.M. Hessel R.L. Coffman Therapeutic targeting of innate immunity with Toll-like receptor agonists and antagonists Nat. Med. 13 2007 552 559
5. S.H.E. Kaufmann The contribution of immunology to the rational design of novel antibacterial vaccines Nat. Rev. Microbiol. 5 2007 491 504
6. M.G. Netea C. van der Graaf J.W.M. Van der Meer B.J. Kullberg Toll-like receptors and the host defense against microbial pathogens: bringing specificity to the innate-immune system J. Leukocyte Biol. 75 2004 749 755
7. B. Verstak P. Hertzog A. Mansell Toll-like receptor signalling and the clinical benefits that lie within Inflammation Res. 56 2007 1 10
8. J.F. Kearney A. Radbruch B. Liesegang K. Rajewsky A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines J. Immunol. 123 1979 1548 1550
9. R.M. Wooten Y. Ma R.A. Yoder J.P. Brown J.H. Weis J.F. Zachary Toll-like receptor 2 is required for innate, but not acquired, host defense to Borrelia burgdorferi J. Immunol. 168 2002 348 355
10. R. Kontermann S. Dubel Antibody Engineering 2001 Springer New York
11. C.F. Barbas 3rd A.S. Kang R.A. Lerner S.J. Benkovic Assembly of combinatorial antibody libraries on phage surfaces: the gene III site Proc. Natl Acad. Sci. USA 88 1991 7978 7982
12. R.J. Giordano M. Cardo-Vila J. Lahdenranta R. Pasqualini W. Arap Biopanning and rapid analysis of selective interactive ligands Nat. Med. 7 2001 1249 1253
13. J. de Kruif L. Terstappen E. Boel T. Logtenberg Rapid selection of cell subpopulation-specific human monoclonal antibodies from a synthetic phage antibody library Proc. Natl Acad. Sci. USA 92 1995 3938 3942
14. A. Lekkerkerker T. Logtenberg Phage antibodies against human dendritic cell subpopulations obtained by flow cytometry J. Immunol. Methods 231 1999 53 63
15. T.N. Sato Y. Qin C.A. Kozak K.L. Audus Tie2, a putative protein tyrosine kinase from a new class of cell surface receptor Growth Factors 9 1993 99 105
16. S. Tsuchiya M. Yamabe Y. Yamaguchi Y. Kobayashi T. Konno K. Tada Establishment and characterization of a human acute monocytic leukemia cell line (THP-1) Int. J. Cancer 26 1980 171 176
17. C. Jumarie C. Malo Caco-2 cells cultured in serum-free medium as a model for the study of enterocytic differentiation in vitro J. Cell. Physiol. 149 1991 24 33
18. I. Lorimer A. Keppler-Hafkemeyer R. Beers C. Pegram D. Bigner I. Pastan Recombinant immunotoxins specific for a mutant epidermal growth factor receptor: targeting with a single chain antibody variable domain isolated by phage display Proc. Natl Acad. Sci. USA 93 1996 14815 14820
19. D.L. Siegel T.Y. Chang S.L. Russell V.Y. Bunya Isolation of cell surface-specific human monoclonal antibodies using phage display and magnetically-activated cell sorting: applications in immunohematology J. Immunol. Methods 206 1997 73 85
20. B. Reavy A. Ziegler J. Diplexcito S.M. Macintosh L. Torrance M. Mayo Expression of functional recombinant antibody molecules in insect cell expression system Protein Expression Purif. 18 2000 221 228
21. R.B. Kirkpatrick S. Ganguly M. Angelichio S. Griego A. Shatzman C. Silverman M. Rosenberg Heavy chain dimers as well as complete antibodies are efficiently formed and secreted from Drosophila via a BiP-mediated pathway J. Biol. Chem. 270 1995 19800 19805
22. D. Iwaki H. Mitsuzawa S. Murakami H. Sano M. Konishi T. Akino Y. Kuroki The extracellular Toll-like receptor 2 domain directly binds peptidoglycan derived from Staphylococcus aureus J. Biol. Chem. 277 2002 24315 24320
23. D.R. O'Reilly L.K. Miller V.A. Luckow Baculovirus Expression Vector: A Laboratory Manual 1992 W.H. Freeman and Company New York 139 179
24. S.K. Nordone J.W. Peacock S.M. Kirwan H.F. Staats Capric acid and hydroxypropylmethylcellulose increase the immunogenicity of nasally administered peptide vaccines AIDS Res. Hum. Retroviruses 22 2006 558 568
25. C.P. Bradney G.D. Sempowski H.X. Liao B.F. Haynes H.F. Staats Cytokines as adjuvants for the induction of anti-human immunodeficiency virus peptide immunoglobulin G (IgG) and IgA antibodies in serum and mucosal secretions after nasal immunization J. Virol. 76 2002 517 524
26. D. Gussow T. Clackson Direct clone characterization from plaques and colonies by the polymerase chain reaction Nucleic Acids Res. 17 1989 4000 4003