Bone mineral density in children exposed to chronic glucocorticoid therapy

Clinical Pediatrics

Volumn 47, Issue 5, 2008, Pages 469-475

  Cohran, Valeria C ^a   Griffiths, Mark ^b   Heubi, James E ^b  

^a CHILDREN'S MEMORIAL HOSPITAL   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Bone mineral density; Children; Glucocorticoids; Osteoporosis

Indexed keywords

CALCIUM; GLUCOCORTICOID; PREDNISONE; VITAMIN D;

ADOLESCENT; ADULT; ARTICLE; BONE DENSITY; CALCIUM INTAKE; CHILD; CLINICAL ARTICLE; DERMATOMYOSITIS; DRUG EXPOSURE; DUCHENNE MUSCULAR DYSTROPHY; ENTERITIS; FEMALE; GLOMERULUS; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; KIDNEY DISEASE; LONG TERM CARE; LUMBAR SPINE; MALE; ORGAN TRANSPLANTATION; PHYSICAL ACTIVITY; POPULATION; SCORING SYSTEM; SCREENING; VITAMIN BLOOD LEVEL; VITAMIN D DEFICIENCY;

ADOLESCENT; ARTHRITIS, JUVENILE RHEUMATOID; BONE DENSITY; CALCIUM, DIETARY; CHILD; CHILD, PRESCHOOL; CROSS-SECTIONAL STUDIES; DERMATOMYOSITIS; FEMALE; GLUCOCORTICOIDS; HUMANS; INFLAMMATORY BOWEL DISEASES; KIDNEY DISEASES; KIDNEY GLOMERULUS; LUMBAR VERTEBRAE; MALE; MOTOR ACTIVITY; MUSCULAR DYSTROPHY, DUCHENNE; OSTEOPOROSIS; PREDNISONE; TRANSPLANTS; VITAMIN D;

EID: 43049111398     PISSN: 00099228     EISSN: None     Source Type: Journal    
DOI: 10.1177/0009922807311732     Document Type: Article

References (18)

1. National Osteoporosis Foundation. Fast Facts on Osteoporosis. 2006. Available at: http://www.nof.org/osteoporosis/diseasefacts.htm. Accessed October 5, 2007.
2. Conway SP, Morton AM, Oldroyd B., et al. Osteoporosis and osteopenia in adults and adolescents with cystic fibrosis: prevalence and associated factors. Thorax. 2000 ; 55: 798-804.
3. Saag KG, Emkey R., Schnitzer TJ,, et al. Glucocorticoid-Induced Osteoporosis Intervention Study Group. Alendronate for the prevention and treatment of glucocorticoid-induced osteoporosis. N Engl J Med. 1998 ; 339: 292-299.
4. Boutsen Y., Jamart J., Esselinckx W., Devogelaer JP Primary prevention of glucocorticoid-induced osteoporosis with intravenous pamidronate and calcium: a prospective controlled 1-year study comparing a single infusion, an infusion given once every 3 months, and calcium alone. J Bone Miner Res. 2001 ; 16: 104-112.
5. Hamburg SM, Piers DA, van den Berg AP, Slooff MJ, Haagsma EB Bone mineral density in the long term after liver transplantation. Osteoporos Int. 2000 ; 11: 600-606.
6. Slemenda CW, Miller JZ, Hui SL, Reister TK, Johnston CC Jr. Role of physical activity in the development of skeletal mass in children. J Bone Miner Res. 1991 ; 6: 1227-1233.
7. Zemel BS, Leonard MB, Kalkwarf HJ, et al. Reference data for the whole body, lumbar spine and proximal femur for American children relative to age, gender, and body size. J Bone Miner Res. 2004 ; 19 (suppl 1). S231.
8. Bianchi ML, Cimaz R., Bardare M., et al. Efficacy and safety of alendronate for the treatment of osteoporosis in diffuse connective tissue diseases in children: a prospective multicenter study. Arthritis Rheum. 2000 ; 43: 1960-1966.
9. Gokhale R., Favus MJ, Karrison T., Sutton MM, Rich B., Kirschner BS Bone mineral density assessment in children with inflammatory bowel disease. Gastroenterology. 1998 ; 114: 902-911.
10. Guthery SL, Pohl JF, Bucuvalas JC, et al. Bone mineral density in long-term survivors following pediatric liver transplantation. Liver Transpl. 2003 ; 9: 365-370.
11. Leonard MB, Feldman HI, Shults J., Zemel BS, Foster BJ, Stallings VA Long-term, high-dose glucocorticoids and bone mineral content in childhood glucocorticoid-sensitive nephrotic syndrome. N Engl J Med. 2004 ; 351: 868-875.
12. Semeao EJ, Jawad AF, Stouffer NO, Zemel BS, Piccoli DA, Stallings VA Risk factors for low bone mineral density in children and young adults with Crohn's disease. J Pediatr. 1999 ; 135: 593-600.
13. Lehtonen-Veromaa MK, Mottonen TT, Nuotio IO, Irjala KM, Leino AE, Viikari JS Vitamin D and attainment of peak bone mass among peripubertal Finnish girls: a 3-y prospective study. Am J Clin Nutr. 2002 ; 76: 1446-1453.
14. Hollis B. Circulating 25-hydroxyvitamin D levels indicative of vitamin D sufficiency: implications for establishing a new effective dietary intake recommendation for vitamin D. J Nutr. 2005 ; 135: 332-337.
15. Rowlands AV, Ingledew DK, Powell SM, Eston RG Interactive effects of habitual physical activity and calcium intake on bone density in boys and girls. J Appl Physiol. 2004 ; 97: 1203-1208.
16. Kalkwarf HJ, Khoury JC, Lanphear BP Milk intake during childhood and adolescence, adult bone density, and osteoporotic fractures in US women. Am J Clin Nutr. 2003 ; 77: 257-265.
17. Van Staa TP, Cooper C., Leufkens HG, Bishop N. Children and the risk of fractures caused by oral corticosteroids. J Bone Miner Res. 2003 ; 18: 913-918.
18. National Institutes of Health. Osteoporosis prevention, diagnosis, and therapy. 2000. Available at: http://consensus.nih.gov/2000/ 2000Osteoporosis111html.htm. Accessed October 5, 2007.