Clinical heterogeneity in sodium channelopathies: What is the meaning of carrying a genetic mutation?

Cardiology

Volumn 110, Issue 2, 2008, Pages 116-122

  Oliva, Antonio ^a   Bjerregaard, Preben ^b   Hong, Kui ^c   Evans, Steven ^d   Vernooy, Kevin ^e   McCormack, Jorge ^f   Brugada, Josep ^g   Brugada, Pedro ^h   Pascali, Vincenzo L ^a   Brugada, Ramon ⁱ  

^a CATHOLIC UNIVERSITY   (Italy)

^b SAINT LOUIS UNIVERSITY HOSPITAL   (United States)

^c NANCHANG UNIVERSITY   (China)

^d BETH ISRAEL MEDICAL CENTER   (United States)

^e MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^f Pediatric Cardiology Associates   (United States)

^g HOSPITAL CLÍNIC   (Spain)

^h Free University of Brussels ^*  (Belgium)

ⁱ MONTREAL HEART INSTITUTE   (Canada)

Author keywords

Brugada syndrome; SCN5A; Sudden cardiac death; Ventricular fibrillation

Indexed keywords

PROTEIN SCN5A; SODIUM CHANNEL;

ADOLESCENT; ADULT; AGED; ARTICLE; BRUGADA SYNDROME; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; ECG ABNORMALITY; ELECTROCARDIOGRAM; EXON; FAMILY HISTORY; FEMALE; GENE IDENTIFICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; HEART ARREST; HUMAN; INTRON; LONG QT SYNDROME; MALE; PRIORITY JOURNAL; SODIUM CHANNELOPATHY; SUDDEN DEATH;

BRUGADA SYNDROME; CHILD; DEATH, SUDDEN, CARDIAC; ELECTROCARDIOGRAPHY; FATAL OUTCOME; FEMALE; FRAMESHIFT MUTATION; GENETIC HETEROGENEITY; HUMANS; LONG QT SYNDROME; MUSCLE PROTEINS; MUTATION, MISSENSE; PEDIGREE; SEQUENCE ANALYSIS, DNA; SODIUM CHANNELS;

EID: 43049105050     PISSN: 00086312     EISSN: None     Source Type: Journal    
DOI: 10.1159/000110490     Document Type: Article

References (13)

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