Quantitative determination of besifloxacin, a novel fluoroquinolone antimicrobial agent, in human tears by liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 867, Issue 1, 2008, Pages 105-110

  Arnold, Dana R ^a   Granvil, Camille P ^a   Ward, Keith W ^a   Proksch, Joel W ^a  

^a BAUSCH AND LOMB   (United States)

Author keywords

Antimicrobial agent; Besifloxacin; Fluoroquinolone; Human tears; LC MS MS; Pharmacokinetics

Indexed keywords

BODY FLUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MICROORGANISMS; PH;

ANTIMICROBIAL AGENTS; BESIFLOXACIN; FLUOROQUINOLONE; HUMAN TEARS;

PHARMACOKINETICS;

AMMONIUM FORMATE; BESIFLOXACIN; BUFFER; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SPARFLOXACIN;

ARTICLE; DRUG STRUCTURE; HUMAN; LACRIMAL FLUID; LIQUID CHROMATOGRAPHY; PH; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; STANDARD; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

ANTI-BACTERIAL AGENTS; AZEPINES; CALIBRATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FLUOROQUINOLONES; HUMANS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; TEARS;

EID: 43049102370     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2008.03.025     Document Type: Article

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