A physiological model to evaluate drug kinetics in patients with hemorrhagic shock followed by fluid resuscitation: Application to amoxicillin-clavulanate

Pharmaceutical Research

Volumn 25, Issue 6, 2008, Pages 1431-1439

  Tod, Michel ^a,b,c   Lagneau, Franck ^d   Jullien, Vincent ^a,e   Mimoz, Olivier ^f,g  

^a AP HP ^*  (France)

^b UNIVERSITÉ DE LYON   (France)

^c UNIVERSITÉ LYON 1   (France)

^d HENRI MONDOR HOSPITAL   (France)

^e UNIVERSITÉ PARIS DESCARTES   (France)

^f POITIERS UNIVERSITY HOSPITAL   (France)

^g UNIVERSITÉ DE POITIERS   (France)

Author keywords

Amoxicillin; Clavulanate; Hemorrhagic shock; Pharmacokinetics; Physiological model

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID;

ADULT; ARTICLE; BLOOD VOLUME; BODY WATER; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DISTRIBUTION; DRUG HEART LEVEL; DRUG LUNG LEVEL; DRUG MUSCLE LEVEL; DRUG SCREENING; DRUG TISSUE LEVEL; FLUID RESUSCITATION; HEMORRHAGIC SHOCK; HUMAN; INTERSTITIAL FLUID; PREDICTION; PRIORITY JOURNAL; STEADY STATE; TENDON; VOLUNTEER;

ADULT; AMOXICILLIN-POTASSIUM CLAVULANATE COMBINATION; ANTI-BACTERIAL AGENTS; FLUID THERAPY; HUMANS; MODELS, BIOLOGICAL; RESUSCITATION; SHOCK, HEMORRHAGIC;

EID: 43049091491     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-008-9546-y     Document Type: Article

References (36)