IGF-1 protects against dexamethasone-induced cell death in insulin secreting INS-1 cells independent of AKT/PKB phosphorylation

Cellular Physiology and Biochemistry

Volumn 21, Issue 5-6, 2008, Pages 455-462

  Avram, Diana ^a   Ranta, Felicia ^a   Hennige, Anita M ^b   Berchtold, Susanne ^a,b   Hopp, Sabine ^b   Häring, Hans Ulrich ^b   Lang, Florian ^a   Ullrich, Susanne ^a,b  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

Apoptosis; Dexamethasone; ERK; Insulin secreting cells; IRS 2; Phosphorylation; PI3K; PKB Akt; Proliferation

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 2 MORPHOLINO 8 PHENYLCHROMONE; BROXURIDINE; DEXAMETHASONE; INSULIN GROWTH FACTOR 1; INSULIN RECEPTOR SUBSTRATE 2; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; SOMATOMEDIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL GROWTH; CELL SURVIVAL; CONTROLLED STUDY; GROWTH RATE; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INTERACTION; PROTEIN PHOSPHORYLATION; RAT; WESTERN BLOTTING;

EID: 42949176200     PISSN: 10158987     EISSN: None     Source Type: Journal    
DOI: 10.1159/000129638     Document Type: Article

References (48)