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Volumn 129, Issue 4, 2008, Pages 592-605

Immunohistochemical detection of the von Hippel-Lindau gene product (pVHL) in human tissues and tumors a useful marker for metastatic renal cell carcinoma and clear cell carcinoma of the ovary and uterus

Author keywords

Clear cell carcinoma of ovary and uterus; Metastatic renal cell carcinoma; pVHL; von Hippel Lindau gene product

Indexed keywords

GENE PRODUCT; MONOCLONAL ANTIBODY; POLYCLONAL ANTIBODY; RABBIT ANTISERUM; VON HIPPEL LINDAU PROTEIN; TUMOR MARKER; VHL PROTEIN, HUMAN;

EID: 42949164051     PISSN: 00029173     EISSN: None     Source Type: Journal    
DOI: 10.1309/Q0FLUXFJ4FTTW1XR     Document Type: Article
Times cited : (54)

References (37)
  • 2
    • 33749449442 scopus 로고    scopus 로고
    • Genetic basis of cancer of the kidney
    • Sudarshan S, Linehan WM. Genetic basis of cancer of the kidney. Semin Oncol. 2006;33:544-551.
    • (2006) Semin Oncol , vol.33 , pp. 544-551
    • Sudarshan, S.1    Linehan, W.M.2
  • 3
    • 47749151447 scopus 로고    scopus 로고
    • Eble JN, Togashi K, Pisani P. Renal cell carcinoma. In: Eble JN, Sauter G, Epstein JI, et al, eds. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon, France: IARC Press; 2004:12-43. World Health Organization Classification of Tumours.
    • Eble JN, Togashi K, Pisani P. Renal cell carcinoma. In: Eble JN, Sauter G, Epstein JI, et al, eds. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. Lyon, France: IARC Press; 2004:12-43. World Health Organization Classification of Tumours.
  • 4
    • 19544383068 scopus 로고    scopus 로고
    • Distribution of cytokeratins and vimentin in adult renal neoplasms and normal renal tissue: Potential utility of a cytokeratin antibody panel in the differential diagnosis of renal tumors
    • Skinnider BF, Folpe AL, Hennigar RA, et al. Distribution of cytokeratins and vimentin in adult renal neoplasms and normal renal tissue: potential utility of a cytokeratin antibody panel in the differential diagnosis of renal tumors. Am J Surg Pathol. 2005;29:747-754.
    • (2005) Am J Surg Pathol , vol.29 , pp. 747-754
    • Skinnider, B.F.1    Folpe, A.L.2    Hennigar, R.A.3
  • 5
    • 0033950307 scopus 로고    scopus 로고
    • Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms
    • Avery AK, Beckstead J, Renshaw AA, et al. Use of antibodies to RCC and CD10 in the differential diagnosis of renal neoplasms. Am J Surg Pathol. 2000;24:203-210.
    • (2000) Am J Surg Pathol , vol.24 , pp. 203-210
    • Avery, A.K.1    Beckstead, J.2    Renshaw, A.A.3
  • 6
    • 0034101791 scopus 로고    scopus 로고
    • Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms: Frequent expression in renal cell carcinoma and endometrial stromal sarcoma
    • Chu P, Arber DA. Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms: frequent expression in renal cell carcinoma and endometrial stromal sarcoma. Am J Clin Pathol. 2000;113:374-382.
    • (2000) Am J Clin Pathol , vol.113 , pp. 374-382
    • Chu, P.1    Arber, D.A.2
  • 7
    • 0035184516 scopus 로고    scopus 로고
    • McGregor DK, Khurana KK, Cao C, et al. Diagnosing primary and metastatic renal cell carcinoma: the use of the monoclonal antibody renal cell carcinoma marker. Am J Surg Pathol. 2001;25:1485-1492.
    • McGregor DK, Khurana KK, Cao C, et al. Diagnosing primary and metastatic renal cell carcinoma: the use of the monoclonal antibody "renal cell carcinoma marker." Am J Surg Pathol. 2001;25:1485-1492.
  • 8
    • 0024519235 scopus 로고
    • Monoclonal antibody to a proximal nephrogenic renal antigen: Immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas
    • Yoshida SO, Imam A. Monoclonal antibody to a proximal nephrogenic renal antigen: immunohistochemical analysis of formalin-fixed, paraffin-embedded human renal cell carcinomas. Cancer Res. 1989;49:1802-1809.
    • (1989) Cancer Res , vol.49 , pp. 1802-1809
    • Yoshida, S.O.1    Imam, A.2
  • 9
    • 0030835515 scopus 로고    scopus 로고
    • Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney
    • Liao SY, Aurelio ON, Jan K, et al. Identification of the MN/CA9 protein as a reliable diagnostic biomarker of clear cell carcinoma of the kidney. Cancer Res. 1997;57:2827-2831.
    • (1997) Cancer Res , vol.57 , pp. 2827-2831
    • Liao, S.Y.1    Aurelio, O.N.2    Jan, K.3
  • 10
    • 0041886959 scopus 로고    scopus 로고
    • Expression of α-methylacyl-CoA racemase (P504S) in various malignant neoplasms and normal tissues: A study of 761 cases
    • Jiang Z, Fanger GR, Woda BA, et al. Expression of α-methylacyl-CoA racemase (P504S) in various malignant neoplasms and normal tissues: a study of 761 cases. Hum Pathol. 2003;34:792-796.
    • (2003) Hum Pathol , vol.34 , pp. 792-796
    • Jiang, Z.1    Fanger, G.R.2    Woda, B.A.3
  • 11
    • 2942720647 scopus 로고    scopus 로고
    • Immunohistochemical detection of P504S in primary and metastatic renal cell carcinomas
    • Lin F, Brown RE, Shen T, et al. Immunohistochemical detection of P504S in primary and metastatic renal cell carcinomas. Appl Immunohistochem Mol Morphol. 2004;12:153-159.
    • (2004) Appl Immunohistochem Mol Morphol , vol.12 , pp. 153-159
    • Lin, F.1    Brown, R.E.2    Shen, T.3
  • 12
    • 0242521464 scopus 로고    scopus 로고
    • Molecular subclassification of kidney tumors and the discovery of new diagnostic markers
    • Takahashi M, Yang XJ, Sugimura J, et al. Molecular subclassification of kidney tumors and the discovery of new diagnostic markers. Oncogene. 2003;22:6810-6818.
    • (2003) Oncogene , vol.22 , pp. 6810-6818
    • Takahashi, M.1    Yang, X.J.2    Sugimura, J.3
  • 13
    • 33646662878 scopus 로고    scopus 로고
    • Immunophenotyping of renal cell neoplasms using a tissue microarray
    • Abstract 767
    • Tretiakova M, Turkyilmaz M, Chekmareva M, et al. Immunophenotyping of renal cell neoplasms using a tissue microarray. Mod Pathol. 2002;15:184A. Abstract 767.
    • (2002) Mod Pathol , vol.15
    • Tretiakova, M.1    Turkyilmaz, M.2    Chekmareva, M.3
  • 14
    • 0346158080 scopus 로고    scopus 로고
    • Expression of alpha-methylacyl-CoA racemase in papillary renal cell carcinoma
    • Tretiakova MS, Sahoo S, Takahashi M, et al. Expression of alpha-methylacyl-CoA racemase in papillary renal cell carcinoma. Am J Surg Pathol. 2004;28:69-76.
    • (2004) Am J Surg Pathol , vol.28 , pp. 69-76
    • Tretiakova, M.S.1    Sahoo, S.2    Takahashi, M.3
  • 15
    • 20044364767 scopus 로고    scopus 로고
    • Overexpression of glutathione S-transferase alpha; in clear cell renal cell carcinoma
    • Chuang ST, Chu P, Sugimura J, et al. Overexpression of glutathione S-transferase alpha; in clear cell renal cell carcinoma. Am J Clin Pathol. 2005;123:421-429.
    • (2005) Am J Clin Pathol , vol.123 , pp. 421-429
    • Chuang, S.T.1    Chu, P.2    Sugimura, J.3
  • 16
    • 33645116503 scopus 로고    scopus 로고
    • Expression of S-100 protein in renal cell neoplasms
    • Lin F, Yang WN, Yang XJ, et al. Expression of S-100 protein in renal cell neoplasms. Hum Pathol. 2006;37:460-470.
    • (2006) Hum Pathol , vol.37 , pp. 460-470
    • Lin, F.1    Yang, W.N.2    Yang, X.J.3
  • 17
    • 34247589885 scopus 로고    scopus 로고
    • Human kidney injury molecule-1 (hKIM-1): A useful immunohistochemical marker for diagnosing renal cell carcinoma and ovarian clear cell carcinoma
    • Lin F, Zhang PL, Yang XJ, et al. Human kidney injury molecule-1 (hKIM-1): a useful immunohistochemical marker for diagnosing renal cell carcinoma and ovarian clear cell carcinoma. Am J Surg Pathol. 2007;42:371-381.
    • (2007) Am J Surg Pathol , vol.42 , pp. 371-381
    • Lin, F.1    Zhang, P.L.2    Yang, X.J.3
  • 18
    • 0036718539 scopus 로고    scopus 로고
    • Molecular basis of the VHL hereditary cancer syndrome
    • Kaelin WG Jr. Molecular basis of the VHL hereditary cancer syndrome. Nat Rev Cancer. 2002;2:673-682.
    • (2002) Nat Rev Cancer , vol.2 , pp. 673-682
    • Kaelin Jr., W.G.1
  • 19
    • 33749451610 scopus 로고    scopus 로고
    • Molecular pathways in renal cell carcinoma: Rationale for targeted treatment
    • Kim WY, Kaelin WG Jr. Molecular pathways in renal cell carcinoma: rationale for targeted treatment. Semin Oncol. 2006;33:588-595.
    • (2006) Semin Oncol , vol.33 , pp. 588-595
    • Kim, W.Y.1    Kaelin Jr., W.G.2
  • 20
    • 33947162517 scopus 로고    scopus 로고
    • Identification of novel VHL targets that are associated with the development of renal cell carcinoma
    • Abdulrahman M, Maina EN, Morris MR, et al. Identification of novel VHL targets that are associated with the development of renal cell carcinoma. Oncogene. 2006;26:1661-1672.
    • (2006) Oncogene , vol.26 , pp. 1661-1672
    • Abdulrahman, M.1    Maina, E.N.2    Morris, M.R.3
  • 21
    • 0029090338 scopus 로고
    • Tumour suppression by the human von Hippel-Lindau gene product
    • Iliopoulos O, Kibel A, Gray S, et al. Tumour suppression by the human von Hippel-Lindau gene product. Nat Med. 1995;1:822-826.
    • (1995) Nat Med , vol.1 , pp. 822-826
    • Iliopoulos, O.1    Kibel, A.2    Gray, S.3
  • 22
    • 0032578357 scopus 로고    scopus 로고
    • pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation
    • Iliopoulos O, Ohh M, Kaelin WG Jr. pVHL19 is a biologically active product of the von Hippel-Lindau gene arising from internal translation initiation. Proc Natl Acad Sci U S A. 1998;95:11661-11666.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 11661-11666
    • Iliopoulos, O.1    Ohh, M.2    Kaelin Jr, W.G.3
  • 23
    • 0030948396 scopus 로고    scopus 로고
    • Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues
    • Corless CL, Kibel AS, Iliopoulos O, et al. Immunostaining of the von Hippel-Lindau gene product in normal and neoplastic human tissues. Hum Pathol. 1997;28:459-464.
    • (1997) Hum Pathol , vol.28 , pp. 459-464
    • Corless, C.L.1    Kibel, A.S.2    Iliopoulos, O.3
  • 24
    • 0029946004 scopus 로고    scopus 로고
    • Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density
    • Lee S, Chen DY, Humphrey JS, et al. Nuclear/cytoplasmic localization of the von Hippel-Lindau tumor suppressor gene product is determined by cell density. Proc Natl Acad Sci U S A. 1996;93:1770-1775.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 1770-1775
    • Lee, S.1    Chen, D.Y.2    Humphrey, J.S.3
  • 25
    • 0029772338 scopus 로고    scopus 로고
    • Expression pattern of the von Hippel-Lindau protein in human tissues
    • Los M, Jansen GH, Kaelin WG, et al. Expression pattern of the von Hippel-Lindau protein in human tissues. Lab Invest. 1996;75:231-238.
    • (1996) Lab Invest , vol.75 , pp. 231-238
    • Los, M.1    Jansen, G.H.2    Kaelin, W.G.3
  • 26
    • 0033052893 scopus 로고    scopus 로고
    • Expression of von Hippel-Lindau protein in normal and pathological human tissues
    • Sakashita N, Takeya M, Kishida T, et al. Expression of von Hippel-Lindau protein in normal and pathological human tissues. Histochem J. 1999;31:133-144.
    • (1999) Histochem J , vol.31 , pp. 133-144
    • Sakashita, N.1    Takeya, M.2    Kishida, T.3
  • 27
    • 0042425755 scopus 로고    scopus 로고
    • Relevance of nuclear and cytoplasmic von Hippel Lindau protein expression for renal carcinoma progression
    • Schraml P, Hergovich A, Hatz F, et al. Relevance of nuclear and cytoplasmic von Hippel Lindau protein expression for renal carcinoma progression. Am J Pathol. 2003;163:1013-1020.
    • (2003) Am J Pathol , vol.163 , pp. 1013-1020
    • Schraml, P.1    Hergovich, A.2    Hatz, F.3
  • 28
    • 0031869573 scopus 로고    scopus 로고
    • Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent
    • Ye Y, Vasavada S, Kuzmin I, et al. Subcellular localization of the von Hippel-Lindau disease gene product is cell cycle-dependent. Int J Cancer. 1998;78:62-69.
    • (1998) Int J Cancer , vol.78 , pp. 62-69
    • Ye, Y.1    Vasavada, S.2    Kuzmin, I.3
  • 29
    • 0036178508 scopus 로고    scopus 로고
    • Tissue microarrays: A powerful tool for high-throughput analysis of clinical specimens: a review of the method with validation data
    • Skacel M, Skilton B, Pettay JD, et al. Tissue microarrays: a powerful tool for high-throughput analysis of clinical specimens: a review of the method with validation data. Applied Immunohistochem Mol Morphol. 2002;10:1-6.
    • (2002) Applied Immunohistochem Mol Morphol , vol.10 , pp. 1-6
    • Skacel, M.1    Skilton, B.2    Pettay, J.D.3
  • 30
    • 33144489901 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers
    • Hebert C, Norris K, Parashar P, et al. Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers. Mol Cancer. 2006;5:1-11.
    • (2006) Mol Cancer , vol.5 , pp. 1-11
    • Hebert, C.1    Norris, K.2    Parashar, P.3
  • 31
    • 0037709883 scopus 로고    scopus 로고
    • von Hippel-Lindau disease
    • Lonser RR, Glenn GM, Walther M, et al. von Hippel-Lindau disease. Lancet. 2003;361:2059-2067.
    • (2003) Lancet , vol.361 , pp. 2059-2067
    • Lonser, R.R.1    Glenn, G.M.2    Walther, M.3
  • 32
    • 0025872333 scopus 로고
    • Genetic flanking markers refine diagnostic criteria and provide insights into the genetics of von Hippel Lindau disease
    • Seizinger BR, Smith DI, Filling-Katz MR, et al. Genetic flanking markers refine diagnostic criteria and provide insights into the genetics of von Hippel Lindau disease. Proc Natl Acad Sci U S A. 1991;88:2864-2868.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 2864-2868
    • Seizinger, B.R.1    Smith, D.I.2    Filling-Katz, M.R.3
  • 33
    • 0029061518 scopus 로고
    • Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene
    • Kuzmin I, Duh FM, Latif F, et al. Identification of the promoter of the human von Hippel-Lindau disease tumor suppressor gene. Oncogene. 1995;10:2185-2194.
    • (1995) Oncogene , vol.10 , pp. 2185-2194
    • Kuzmin, I.1    Duh, F.M.2    Latif, F.3
  • 34
    • 10544244175 scopus 로고    scopus 로고
    • Von Hippel-Lindau tumour suppressor gene: Localization of expression by in situ hybridization
    • Nagashima Y, Miyagi Y, Udagawa K, et al. Von Hippel-Lindau tumour suppressor gene: localization of expression by in situ hybridization. J Pathol. 1996;180:271-274.
    • (1996) J Pathol , vol.180 , pp. 271-274
    • Nagashima, Y.1    Miyagi, Y.2    Udagawa, K.3
  • 35
    • 47749089332 scopus 로고    scopus 로고
    • Expression of S100A4, S100A6, and S100P in pancreatic and ampullary adenocarcinomas [abstract]
    • Abstract 1313
    • Lin F, Hull ME, Shi J, et al. Expression of S100A4, S100A6, and S100P in pancreatic and ampullary adenocarcinomas [abstract]. Mod Pathol. 2007;20:286A. Abstract 1313.
    • (2007) Mod Pathol , vol.20
    • Lin, F.1    Hull, M.E.2    Shi, J.3
  • 36
    • 0035002922 scopus 로고    scopus 로고
    • Detection of loss of heterozygosity at chromosome 3p25-26 in primary and metastatic ovarian clear-cell carcinoma: Utilization of microdissection and polymerase chain reaction in archival tissues
    • Simsir A, Palacios D, Linehan WM, et al. Detection of loss of heterozygosity at chromosome 3p25-26 in primary and metastatic ovarian clear-cell carcinoma: utilization of microdissection and polymerase chain reaction in archival tissues. Diagn Cytopathol. 2001;24:328-332.
    • (2001) Diagn Cytopathol , vol.24 , pp. 328-332
    • Simsir, A.1    Palacios, D.2    Linehan, W.M.3
  • 37
    • 0038115834 scopus 로고    scopus 로고
    • Cytogenetic alterations in ovarian clear cell carcinoma detected by comparative genomic hybridization
    • Dent J, Hall GD, Wilkinson N, et al. Cytogenetic alterations in ovarian clear cell carcinoma detected by comparative genomic hybridization. Br J Cancer. 2003;88:1578-1583.
    • (2003) Br J Cancer , vol.88 , pp. 1578-1583
    • Dent, J.1    Hall, G.D.2    Wilkinson, N.3


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