Synthesis, characterization and biological activity of Pt(II) and Pt(IV) complexes with 5-methyl-5(4-pyridyl)-2,4-imidazolidenedione

European Journal of Medicinal Chemistry

Volumn 43, Issue 5, 2008, Pages 958-965

  Bakalova, Adriana ^a   Varbanov, Hristo ^a   Buyukliev, Rossen ^a   Momekov, Georgi ^a   Ferdinandov, Dilyan ^b   Konstantinov, Spiro ^a   Ivanov, Darvin ^a  

^a MEDICAL UNIVERSITY OF SOFIA   (Bulgaria)

^b UNIVERSITY HOSPITAL ALEXANDROVSKA   (Bulgaria)

Author keywords

2,4 Imidazolidenedione; cis trans Pt(II) and Pt(IV) complexes; Cytotoxicity

Indexed keywords

ACETYLCYSTEINE; ASCORBIC ACID; GLUTATHIONE; HYDANTOIN DERIVATIVE; PLATINUM 5 METHYL 5 (4 PYRIDYL) 2,4 IMIDAZOLIDENEDIONE DERIVATIVE; PLATINUM COMPLEX;

ARTICLE; CANCER CELL CULTURE; CARBON NUCLEAR MAGNETIC RESONANCE; CELL STRAIN MCF 7; CHEMICAL ANALYSIS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; INFRARED SPECTROSCOPY; PROTON NUCLEAR MAGNETIC RESONANCE;

ADULT; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CHELATING AGENTS; CHILD; DRUG SCREENING ASSAYS, ANTITUMOR; FEMALE; HUMANS; IMIDAZOLINES; MALE; MIDDLE AGED; PLATINUM; PYRIDINES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 42949162628     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2007.06.025     Document Type: Article

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