Randomized, prospective, and controlled clinical trial of pulsed electromagnetic field stimulation for cervical fusion

Spine Journal

Volumn 8, Issue 3, 2008, Pages 436-442

  Foley, Kevin T ^a   Mroz, Thomas E ^b   Arnold, Paul M ^c   Chandler Jr , Howard C ^d   Dixon, Robert A ^e   Girasole, Gerard J ^f   Renkens Jr , Kenneth L ^g   Riew, K Daniel ^h   Sasso, Rick C ^g   Smith, Richard C ⁱ   Tung, Howard ^j   Wecht, Daniel A ^k   Whiting, Donald M ^l  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

^c UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF MONTANA   (United States)

^e Columbus NeuroSurgical Group ^*  (United States)

^f Orthopaedic and Sports Medicine Center   (United States)

^g INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁱ Florida Center for Orthopedics   (United States)

^j UNIVERSITY OF CALIFORNIA   (United States)

^k UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^l DREXEL UNIVERSITY COLLEGE OF MEDICINE   (United States)

more..

Author keywords

Allograft; Anterior cervical fusion; Multilevel; Pulsed electromagnetic field (PEMF) stimulation; Smoking

Indexed keywords

ADULT; ADVERSE OUTCOME; AGE DISTRIBUTION; AGED; ARTHRODESIS; ARTICLE; BONE ALLOGRAFT; CERVICAL SPINE; CERVICOBRACHIAL NEURALGIA; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; ELECTROMAGNETIC RADIATION; FEMALE; FOLLOW UP; GENDER; HUMAN; INTERVERTEBRAL DISK HERNIA; INTERVERTEBRAL DISKECTOMY; LAW SUIT; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; MYELOGRAPHY; NERVE ROOT COMPRESSION; NERVE STIMULATION; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PLATE FIXATION; POSTOPERATIVE CARE; PRIORITY JOURNAL; PSEUDARTHROSIS; PULSED ELECTROMAGNETIC FIELD STIMULATION; RACE; RADIODIAGNOSIS; RADIOLOGIST; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SHOULDER PAIN; SMOKING; SPINE FUSION; SPONDYLOSIS; STATISTICAL SIGNIFICANCE; SURGEON; SURGICAL TECHNIQUE; VISUAL ANALOG SCALE;

ADULT; AGED; CERVICAL VERTEBRAE; COMBINED MODALITY THERAPY; DECOMPRESSION, SURGICAL; ELECTRIC STIMULATION THERAPY; FEMALE; HUMANS; MAGNETICS; MALE; MIDDLE AGED; PAIN; PROSPECTIVE STUDIES; RADICULOPATHY; RECOVERY OF FUNCTION; SMOKING; SPINAL FUSION; TRANSPLANTATION, HOMOLOGOUS; TREATMENT OUTCOME;

EID: 42949156273     PISSN: 15299430     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.spinee.2007.06.006     Document Type: Article

References (27)

1. Bose B. Outcomes after posterolateral lumbar fusion with instrumentation in patients treated with adjunctive pulsed electromagnetic field stimulation. Adv Ther 18 (2001) 12-20
2. Mooney V. A randomized double-blind prospective study of the efficacy of pulsed electromagnetic fields for interbody lumbar fusions. Spine 15 (1990) 708-712
3. Silver R.A. Application of pulsed electromagnetic fields (PEMF) after lumbar interbody or posterolateral spinal fusion surgery in a heterogenous patient population. J Neurol Orthop Med Surg 21 (2001) 51-62
4. Shen AC, Foley KT, Murphy M. Pulsed electromagnetic field stimulation increases multilevel cervical fusion rates. Proceedings of the Cervical Spine Research Society, 27th Annual Meeting 1999: A299.
5. Floyd T., and Ohnmeiss D. A meta-analysis of autograft versus allograft in anterior cervical fusion. Eur Spine J 9 (2000) 398-403
6. Malloy K.M., and Hilibrand A.S. Autograft versus allograft in degenerative cervical disease. Clin Orthop Relat Res (2002) 27-38
7. Bolesta M.J., Rechtine II G.R., and Chrin A.M. Three- and four-level anterior cervical discectomy and fusion with plate fixation: a prospective study. Spine 25 (2000) 2040-2044 discussion 2045-6
8. Wang J.C., McDonough P.W., Kanim L.E., Endow K.K., and Delamarter R.B. Increased fusion rates with cervical plating for three-level anterior cervical discectomy and fusion. Spine 26 (2001) 643-646 discussion 646-7
9. Hilibrand A.S., Fye M.A., Emery S.E., Palumbo M.A., and Bohlman H.H. Impact of smoking on the outcome of anterior cervical arthrodesis with interbody or strut-grafting. J Bone Joint Surg Am 83-A (2001) 668-673
10. Kaiser M.G., Haid Jr. R.W., Subach B.R., Barnes B., and Rodts Jr. G.E. Anterior cervical plating enhances arthrodesis after discectomy and fusion with cortical allograft. Neurosurgery 50 (2002) 229-236 discussion 236-8
11. Martin Jr. G.J., Haid Jr. R.W., MacMillan M., Rodts Jr. G.E., and Berkman R. Anterior cervical discectomy with freeze-dried fibula allograft. Overview of 317 cases and literature review. Spine 24 (1999) 852-858 discussion 858-9
12. Samartzis D., Shen F.H., Matthews D.K., Yoon S.T., Goldberg E.J., and An H.S. Comparison of allograft to autograft in multilevel anterior cervical discectomy and fusion with rigid plate fixation. Spine J 3 (2003) 451-459
13. Connolly P.J., Esses S.I., and Kostuik J.P. Anterior cervical fusion: outcome analysis of patients fused with and without anterior cervical plates. J Spinal Disord 9 (1996) 202-206
14. Baskin D.S., Ryan P., Sonntag V., Westmark R., and Widmayer M.A. A prospective, randomized, controlled cervical fusion study using recombinant human bone morphogenetic protein-2 with the CORNERSTONE-SR allograft ring and the ATLANTIS anterior cervical plate. Spine 28 (2003) 1219-1225 discussion 1225
15. Kostuik J.P., Connolly P.J., Esses S.I., and Suh P. Anterior cervical plate fixation with the titanium hollow screw plate system. Spine 18 (1993) 1273-1278
16. Schneeberger A.G., Boos N., Schwarzenbach O., and Aebi M. Anterior cervical interbody fusion with plate fixation for chronic spondylotic radiculopathy: a 2- to 8-year follow-up. J Spinal Disord 12 (1999) 215-220 discussion 221
17. Cauthen J.C., Kinard R.E., Vogler J.B., Jackson D.E., DePaz O.B., Hunter O.L., et al. Outcome analysis of noninstrumented anterior cervical discectomy and interbody fusion in 348 patients. Spine 23 (1998) 188-192
18. Bose B. Anterior cervical instrumentation enhances fusion rates in multilevel reconstruction in smokers. J Spinal Disord 14 (2001) 3-9
19. Bassett C.A., Pilla A.A., and Pawluk R.J. A non-operative salvage of surgically-resistant pseudoarthroses and non-unions by pulsing electromagnetic fields. A preliminary report. Clin Orthop Relat Res (1977) 128-143
20. Guizzardi S., Di Silvestre M., Govoni P., and Scandroglio R. Pulsed electromagnetic field stimulation on posterior spinal fusions: a histological study in rats. J Spinal Disord 7 (1994) 36-40
21. Bassett C.A., Mitchell S.N., and Schink M.M. Treatment of therapeutically resistant non-unions with bone grafts and pulsing electromagnetic fields. J Bone Joint Surg Am 64 (1982) 1214-1220
22. Johnston II C.E., Ashman R.B., Baird A.M., and Allard R.N. Effect of spinal construct stiffness on early fusion mass incorporation. Experimental study. Spine 15 (1990) 908-912
23. Kold S.E., Hickman J., and Meisen F. Preliminary study of quantitative aspects and the effect of pulsed electromagnetic field treatment on the incorporation of equine cancellous bone grafts. Equine Vet J 19 (1987) 120-124
24. Frank C., Schachar N., Dittrich D., Shrive N., deHaas W., and Edwards G. Electromagnetic stimulation of ligament healing in rabbits. Clin Orthop Relat Res (1983) 263-272
25. Binder A., Parr G., Hazleman B., and Fitton-Jackson S. Pulsed electromagnetic field therapy of persistent rotator cuff tendinitis. A double-blind controlled assessment. Lancet 1 (1984) 695-698
26. Orgel M.G., O'Brien W.J., and Murray H.M. Pulsing electromagnetic field therapy in nerve regeneration: an experimental study in the cat. Plast Reconstr Surg 73 (1984) 173-183
27. Mishima S. The effect of long-term pulsing electromagnetic field stimulation on experimental osteoporosis of rats. J UOEH 10 (1988) 31-45