Efficacy of SPK-843, a novel polyene antifungal, in a murine model of systemic cryptococcosis

Antimicrobial Agents and Chemotherapy

Volumn 52, Issue 5, 2008, Pages 1871-1872

  Kakeya, Hiroshi ^a   Miyazaki, Yoshitsugu ^b   Senda, Hisato ^c   Kobayashi, Tsutomu ^a   Seki, Masafumi ^a   Izumikawa, Koichi ^a   Yamamoto, Yoshihiro ^a   Yanagihara, Kazunori ^a   Tashiro, Takayoshi ^a   Kohno, Shigeru ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

^b NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^c KAKEN PHARMACEUTICAL CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; AMPHOTERICIN B DEOXYCHOLATE; ANTIFUNGAL AGENT; FLUCONAZOLE; POLYENE ANTIBIOTIC AGENT; SPK 843;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DRUG EFFICACY; DRUG SCREENING; DRUG TOLERABILITY; FEMALE; HISTOPATHOLOGY; KIDNEY PARENCHYMA; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; SURVIVAL TIME; SYSTEMIC MYCOSIS;

ANIMALS; ANTIFUNGAL AGENTS; BRAIN; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE MODELS, ANIMAL; FEMALE; MICE; MICE, INBRED BALB C; POLYENES;

EID: 42949155145     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.01370-07     Document Type: Article

References (8)

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