Erythrocyte dematin is a candidate gene for Marie Unna hereditary hypotrichosis and related hairloss disorders

American Journal of Hematology

Volumn 83, Issue 5, 2008, Pages 430-432

  Mohseni, Morvarid ^a   Chishti, Athar H ^a  

^a UNIVERSITY OF ILLINOIS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ERYTHROCYTE BAND 4.9 PROTEIN; FRIZZLED PROTEIN; GENE PRODUCT; PROTEIN SH3;

ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; CHROMOSOME 1; CHROMOSOME 8P; CONTROLLED STUDY; DNA SYNTHESIS; EPB49 GENE; GENE; GENE LOCATION; GENE LOCUS; GENE MAPPING; GENETIC SCREENING; HAIR LOSS; HR GENE; HYPOTRICHOSIS; LETTER; MARIE UNNA HEREDITARY HYPOTRICHOSIS; MOUSE; MUHH GENE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL;

ADIPOCYTES; ANIMALS; BLOOD PROTEINS; CHROMOSOME MAPPING; CHROMOSOMES, HUMAN, PAIR 8; FIBROBLASTS; HUMANS; HYPOTRICHOSIS; MICE; MICE, KNOCKOUT; PHOSPHOPROTEINS; PROTEIN STRUCTURE, TERTIARY; SKIN;

EID: 42949143521     PISSN: 03618609     EISSN: 10968652     Source Type: Journal    
DOI: 10.1002/ajh.21153     Document Type: Letter

References (15)

1. Ahmad W, Faiyaz ul Haque M, Brancolini V, et al. Alopecia universalis associated with a mutation in the human hairless gene. Science 1998;279:720-724.
2. Herzer P, Czarnetzki BM, Holzmann H, Lemmel EM. Immunological studies in patients with alopecia areata. Int Arch Allergy Appl Immunol 1979;58:212-218.
3. Wiedemeyeer K, Schill WB, Loser C. Diseases on hair follicles leading to hair loss. Part I. Nonscarring alopecias. Skinmed 2004;3:209-214.
4. Stevanovic DV. Hereditary hypotrichosis congenita: Marie Unna type. Br J Dermatol 1970;83:331-337.
5. Celik HH, Surucu SH, Aldur MM, et al. Light and scanning electron microscopic examination of late changes in hair with hereditary trichodysplasia (Marie Unna hypotrichosis). Saudi Med J 2004;25:1648-1651.
6. Cichon S, Kruse R, Hillmer AM, et al. A distinct gene close to the hairless locus on chromosome 8p underlies hereditary Marie Unna type hypotrichosis in a German family. Br J Dermatol 2000;143:811-814.
7. van Steensel M, Smith FJ, Steijlen PM, et al. The gene for hypotrichosis of Marie Unna maps between D8S258 and D8S298: Exclusion of the hr gene by cDNA and genomic sequencing. Am J Hum Genet 1999;65:413-419.
8. He PP, Zhang XJ, Yang Q, et al. Refinement of a locus for Marie Unna hereditary hypotrichosis to a 1.1-cM interval at 8p21.3. Br J Dermatol 2004;150:837-842.
9. Lefevre P, Rochat A, Bodemer C, et al. Linkage of Marie-Unna hypotrichosis locus to chromosome 8p21 and exclusion of 10 genes including the hairless gene by mutation analysis. Eur J Hum Genet 2000;8:273-279.
10. Yang S, Gao M, Cui Y, et al. Identification of a novel locus for Marie Unna hereditary hypotrichosis to a 17.5 cM interval at 1p21.1-1q21.3. J Invest Dermatol 2005;125:711-714.
11. Hung BS, Wang XQ, Cam GR, Rothnagel JA. Characterization of mouse Frizzled-3 expression in hair follicle development and identification of the human homolog in keratinocytes. J Invest Dermatol 2001;16:940-946.
12. Azim AC, Knoll JH, Beggs AH, Chishti AH. Isoform cloning, actin binding, and chromosomal localization of human erythroid dematin, a member of the villin superfamily. J Biol Chem 1995;270:17407-17413.
13. Peters LL, Eicher EM, Azim AC, Chishti AH. The gene encoding the erythrocyte membrane skeleton protein dematin (Epb4.9) maps to mouse chromosome 14. Genomics 1995;26:634-635.
14. Khanna R, Chang SH, Andrabi S, et al. Headpiece domain of dematin is required for the stability of the erythrocyte membrane. Proc Natl Acad Sci USA 2002;99:6637-6642.
15. Kantor J, Kessler LJ, Brooks DG, Cotsarelis G. Decreased serum ferritin is associated with alopecia in women. J Invest Dermatol. 2003;121:985-988.