Relationship between eNOS gene G894T polymorphism and essential hypertension complicating stroke in Mongolian patients

Chinese Journal of Cerebrovascular Diseases

Volumn 5, Issue 4, 2008, Pages 167-177

  Zhao, Shi Gang ^a   Hu, Ri Le ^b   Niu, Guang Ming ^b   Zhang, Chun Yu ^b   Wang, Zhi Guang ^b   Jiang, Ming Fang ^b  

^a INNER MONGOLIA MEDICAL COLLEGE   (China)

^b NONE

Author keywords

Hypertension; Mongolian; Nitric oxide synthase; Polymorphism

Indexed keywords

ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANINE; THYMINE;

ADULT; AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; CHINESE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DNA POLYMORPHISM; ESSENTIAL HYPERTENSION; FEMALE; GENE FREQUENCY; GENE SEQUENCE; GENETIC ASSOCIATION; GENOTYPE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RISK ASSESSMENT; SEQUENCE ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 42949089851     PISSN: 16725921     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (18)

1. Niwa M, Inao S, Takayasu M, et al. Time course of expression of the three nitric oxide synthase isoforms after transient middle cerebral artery occlusion in rats [J]. Neurol Med Chir (Tokyo), 2001, 41:63-73.
2. Veldman BA, Spiering W, Doevendans PA, et al. The Glu298Asp polymorphism of the NOS 3 gene as a determinant of the baseline production of nitric oxide [J]. J Hypertens,2002,20:2023-2027.
3. Chinese source.
4. Chinese source.
5. Chinese source.
6. Chinese source.
7. Hu CJ, Wang CH, Lee JH, et al. Association between polymorphisms of ACE, B2AR, ANP and ENOS and cardiovascular diseases: a community-based study in the Matsu area[J]. Clin Chem Lab Med,2007,45:20-25.
8. Yamashita T, Kawashima S, Ohashi Y, et al. Mechanisms of reduced nitric oxide/cGMP-mediated vasorelaxation in transgenic mice overexpressing endothelial nitric oxide synthase[J]. Hypertension,2000,36:97-102.
9. Tsukada T,Yokoyama K,Arai T,et al. Evidence of association of the ecNOS gene polymorphism with plasma NO metabolite levels in humans [J]. Biochem Biophys Res Commun,1998,245:190-193.
10. Miyamoto Y, Saito Y, Kajiyama N, et al. Endothelial nitric oxide synthase gene is positively associated with essential hypertension[J]. Hypertension,1998,32:3-8.
11. Lacolley P, Gautier S, Poirier O,et al. Nitric oxide synthase gene polymorphisms, blood pressure and aortic stiffness in normotensive and hypertensive subjects [J]. J Hypertens,1998,16:31-35.
12. Chen W, Srinivasan SR, Elkasabany A, et al. Combined effects of endothelial nitric oxide synthase gene polymorphism (G894T) and insulin resistance status on blood pressure and familial risk of hypertension in young adults: the Bogalusa Heart Study[J]. Am J Hypertens,2001,14: 1046-1052.
13. Tang W, Yang Y, Wang B, et al. Association between a G894T polymorphism of eNOS gene and essential hypertension in Hani and Yi minority groups of China[J]. Arch Med Res,2008,39:222-225.
14. Kishimoto T, Misawa Y, Kaetu A, et al. eNOS Glu298 Asp polymorphism and hypertension in a cohort study in Japanese[J]. Prev Med,2004,39:927-931.
15. Khawaja MR, Taj F, Ahmad U, et al. Association of endothelial nitric oxide synthase gene G894T polymorphism with essential hypertension in an adult Pakistani Pathan population[J]. Int J Cardiol,2007,116:113-115.
16. Chinese source.
17. Karvonen J, Kauma H, Kervinen K, et al. Endothelial nitric oxide synthase gene Glu298Asp polymorphism and blood pressure, left ventricular mass and carotid artery atherosclerosis in a population based cohort [J]. J Intern Med,2002,251:102-110.
18. Szolnoki Z, Havasi V, Bene J, et al. Endothelial nitric oxide synthase gene interactions and the risk of ischaemic stroke[J]. Acta Neurol Scand,2005,111:29-33.