Carcinogenic risk of heterocyclic amines in combination - Assessment with a liver initiation model

Food and Chemical Toxicology

Volumn 46, Issue 6, 2008, Pages 2003-2009

  Hirata, Akihiro ^a,b   Tsukamoto, Tetsuya ^a   Sakai, Hiroki ^a,b   Takasu, Shinji ^a,b   Ban, Hisayo ^a   Imai, Toshio ^c   Totsuka, Yukari ^d   Nishigaki, Rena ^d   Wakabayashi, Keiji ^d   Yanai, Tokuma ^b   Masegi, Toshiaki ^b   Tatematsu, Masae ^a  

^a AICHI CANCER CENTER HOSPITAL   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE OF HEALTH SCIENCES   (Japan)

^d NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

Author keywords

Cytochrome P 450; Glutathione S transferase placental form; Heterocyclic amine; Initiation; Mixture

Indexed keywords

2 AMINO 1 METHYL 6 PHENYLIMIDAZO[4,5 B]PYRIDINE; 2 AMINO 3,8 DIMETHYLIMIDAZO[4,5 F]QUINOXALINE; CYTOCHROME P450 1A1; GLUTATHIONE TRANSFERASE; QUINOXALINE DERIVATIVE;

ANIMAL EXPERIMENT; ARTICLE; CANCER RISK; CARCINOGENIC ACTIVITY; CONTROLLED STUDY; GENE EXPRESSION; IN VIVO STUDY; LIVER; MALE; NONHUMAN; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AMINES; ANIMALS; CARCINOGENS; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 CYP1A2; DNA, COMPLEMENTARY; GLUTATHIONE TRANSFERASE; HEPATOCYTES; HETEROCYCLIC COMPOUNDS; IMIDAZOLES; LIVER; LIVER NEOPLASMS; MALE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; QUINOXALINES; RATS; RATS, INBRED F344; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK;

RATTUS;

EID: 42749094947     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.01.040     Document Type: Article

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