Disappearance of JAK2 V617F mutation in a rapid leukemic transformed essential thrombocythemia patient

Leukemia Research

Volumn 32, Issue 8, 2008, Pages 1323-1324

  Hsiao, Hui Hua ^a,b   Yang, Wen Chi ^a,b   Liu, Yi Chang ^a,b   Lee, Ching Ping ^a,b   Lin, Sheng Fung ^a,b  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

BCR ABL PROTEIN; JANUS KINASE 2;

ACUTE GRANULOCYTIC LEUKEMIA; DISEASE COURSE; GENE MUTATION; HUMAN; LETTER; MYELOID METAPLASIA; PHILADELPHIA CHROMOSOME NEGATIVE CELL; PRIORITY JOURNAL; THROMBOCYTHEMIA;

AGED; AGED, 80 AND OVER; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; JANUS KINASE 2; LEUKEMIA, MYELOID, ACUTE; MUTATION; THROMBOCYTHEMIA, HEMORRHAGIC;

EID: 42749093378     PISSN: 01452126     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.leukres.2007.11.004     Document Type: Letter

References (6)

1. Campbell P.J., and Green A.R. The myeloproliferative disorders. N Engl J Med 355 (2006) 2452-2466
2. Nelson M.E., and Steensma D.P. JAK2 V617F in myeloid disorders: what do we know now, and where are we headed?. Leuk Lymphoma 47 (2006) 177-194
3. Jelinek J., Oki Y., Gharibyan V., et al. JAK2 mutation 1849G > T is rare in acute leukemias but can be found in CMML, Philadelphia chromosome-negative CML, and megakaryocytic leukemia. Blood 106 (2005) 3370-3373
4. Campbell P.J., Baxter E.J., Beer P.A., et al. Mutation of JAK2 in the myeloproliferative disorders: timming, clonality studies, cytogenetic associations, and role in leukemic transformation. Blood 108 (2006) 3548-3555
5. Jones A.V., Kreil S., Zoi K., et al. Widespread occurrence of the JAK2 V617F mutation in chronic myeloproliferative disorders. Blood 106 (2005) 2162-2168
6. Theocharides A., Boissinot M., Girodon F., et al. Leukemic blasts in transformed JAK2-V617F-positive myeloproliferative disorders are frequently negative for the JAK2-V617F mutation. Blood 110 (2007) 375-379