Development of a gas chromatography-time-of-flight mass spectrometry method for the determination of buagafuran, a promising antianxiety drug in dog blood

Journal of Pharmaceutical and Biomedical Analysis

Volumn 47, Issue 2, 2008, Pages 383-387

  Hu, Jinping ^a   Chen, Hui ^a   Li, Yan ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Anxiety disorders; Buagafuran; Dog; Gas chromatography time of flight mass spectrometry (GC ToFMS); Pharmacokinetic

Indexed keywords

4 BUTYL ALPHA AGAROFURAN; AGAROFURAN DERIVATIVE; ANXIOLYTIC AGENT; BUAGAFURAN D4;

ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CAPILLARY COLUMN; CONTROLLED STUDY; DEVICE; DOG; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG DOSE INCREASE; DRUG ISOLATION; ELUTION; FEMALE; GAS CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; SENSITIVITY AND SPECIFICITY; TIME OF FLIGHT MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; ANTI-ANXIETY AGENTS; CALIBRATION; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG STABILITY; FEMALE; FREEZING; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; MALE; MOLECULAR STRUCTURE; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SESQUITERPENES; TIME FACTORS;

EID: 42749091242     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2008.01.021     Document Type: Article

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