Serum C-reactive protein at admission predicts in-hospital mortality in medical patients

European Journal of Internal Medicine

Volumn 19, Issue 4, 2008, Pages 261-265

  Kompoti, M ^a   Drimis, S ^b   Papadaki, A ^b   Kotsomytis, K ^b   Poulopoulou, C ^b   Gianneli, D ^b   Voutsinas, D ^b  

^a EVANGELISMOS HOSPITAL   (Greece)

^b TZANEIO GENERAL HOSPITAL OF PIRAEUS   (Greece)

Author keywords

C reactive protein; Elderly; Infection; Mortality; Systemic inflammatory response syndrome

Indexed keywords

C REACTIVE PROTEIN;

ADULT; AGED; ARTICLE; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEATH; DEMOGRAPHY; FEMALE; GERIATRIC PATIENT; HOSPITAL ADMISSION; HOSPITAL CARE; HOSPITAL PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATICS; MORTALITY; MULTIPLE REGRESSION; OUTCOME ASSESSMENT; PREDICTION; PROBABILITY; PROPORTIONAL HAZARDS MODEL; PROTEIN BLOOD LEVEL;

AGED; AGED, 80 AND OVER; C-REACTIVE PROTEIN; FEMALE; FORECASTING; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; PATIENT ADMISSION;

EID: 42749090187     PISSN: 09536205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejim.2007.06.016     Document Type: Article

References (24)

1. Epstein F.H. Acute-phase proteins and other systemic responses to inflammation. N Engl J Med 340 (1999) 448-454
2. Visser M., Bouter L.M., McQuillan G.M., Wener M.H., and Harris T.B. Elevated C-reactive protein levels in overweight and obese adults. JAMA 282 (1999) 2131-2135
3. Rallidis L.S., Vikelis M., Panagiotakos D.B., Rizos I., Zolindakis M.G., Kaliva K., et al. Inflammatory markers and in-hospital mortality in acute ischaemic stroke. Atherosclerosis 189 (2006) 193-197
4. Montaner J., Fernandez-Cadenas I., Molina C.A., Ribo M., Huertas R., Rosell A., et al. Poststroke C-reactive protein is a powerful prognostic tool among candidates for thrombolysis. Stroke 37 (2006) 1205-1210
5. Winbeck K., Poppert H., Etgen T., Conrad B., and Sander D. Prognostic relevance of early serial C-reactive protein measurements after first ischemic stroke. Stroke 33 (2002) 2459-2464
6. Avram M.M., Fein P.A., Paluch M.M., Schloth T., and Chattopadhyay J. Association between C-reactive protein and clinical outcomes in peritoneal dialysis patients. Adv Perit Dial 21 (2005) 154-158
7. Wang A.Y., Woo J., Lam C.W., Wang M., Sea M.M., Lui S.-F., et al. Is a single time point C-reactive protein predictive of outcome in peritoneal dialysis patients?. J Am Soc Nephrol 14 (2003) 1871-1879
8. Yeun J.Y., Levine R.A., Mantadilok V., and Kaysen G.A. C-reactive protein predicts all-cause and cardiovascular mortality in hemodialysis patients. Am J Kidney Dis 35 (2000) 469-476
9. Liuzzo G., Biasucci L.M., Gallimore J.R., Grillo R.L., Rebuzzi A.G., Pepys M.B., et al. The prognostic value of C-reactive protein and serum amyloid A protein in severe unstable angina. N Engl J Med 331 (1994) 417-424
10. Haverkate F., Thompson S.G., Pyke S.D.M., Gallimore J.R., and Pepys MB for the European Concerted Action on Thrombosis and Disabilities Angina Pectoris Study Group. Production of C-reactive protein and risk of coronary events in stable and unstable angina. Lancet 349 (1997) 462-466
11. Presterl E., Standinger T., Pettermann M., Lassnigg A., Burgmann H., Winkler S., et al. Cytokine profile and correlation to the APACHE III and MPMII scores in patients with sepsis. Am J Respir Crit Care 156 (1997) 825-832
12. Wilson C., Heads A., Shenkin A., and Imrie C.W. C-reactive protein, antiproteases and complement factors as objective markers of severity in acute pancreatitis. Br J Surg 76 (1989) 177-181
13. Neoptolemos J.P., Kemppainen E.A., Mayer J.M., Fitzpatrick J.M., Raraty M.G., Slavin J., et al. Early prediction of severity in acute pancreatitis by urinary trypsinogen activation peptide: a multicentre study. Lancet 355 (2000) 1955-1960
14. Ridker P.M., Cushman M., Stampfer M.J., Tracy R.P., and Hennekens C.H. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 336 (1997) 973-979
15. Rangel-Frausto M.S., Pittet D., Costigan M., Hwang T., Davis C.S., and Wenzel R.P. The natural history of the systemic inflammatory response syndrome (SIRS). A prospective study. JAMA 273 (1995) 117-123
16. Garner J.S., Jarvis W.R., Emon T.C., and Hughes J.M. CDC definitions for nosocomial infections. In: Olmsted R.N. (Ed). APIC Infection Control and Applied Epidemiology: Principles and Practice (1996), Mosby, St. Louis A1-A20
17. In: Haeckel R., Buschm E.W., Jenningsm R.D., and Trucheaudm A. (Eds). Guidelines for the evaluation of an analysis in clinical chemistry: ECCLs Document 3 (1986), Beuth Verlag, Berlin, Germany
18. Sandberg A.A., and Borgström A. Early prediction of severity in acute pancreatitis. Is this possible?. J Pancreas 3 (2002) 116-125
19. Vanderschueren S., Deeren D., Knockaert D.C., Bobbaers H., Bossuyt X., and Peetermans W. Extremely elevated C-reactive protein. Eur J Intern Med 17 (2006) 430-433
20. Wei J., Xu H., Davies J.L., and Hemming G.P. Increase of plasma IL-6 concentration with age in healthy subjects. Life Sci 51 (1992) 1953-1956
21. Daynes R.A., Araneo B.A., Ershler W.B., Maloney C., Li G.-Z., and Ryu S.-Y. Altered regulation of IL-6 production with normal aging. J Immunol 150 (1993) 5219-5230
22. Post D.J., Corter K.C., and Papaconstantinou J. The effect of aging on constitutive mRNA levels and lipopolysaccharide inducibility of acute phase genes. Ann NY Acad Sci 621 (1991) 66-77
23. Ross R.D., and Frengley J.D. Elevated C-reactive protein in older people. J Am Geriat Soc 40 (1992) 104-105
24. Subbe C.P., Kruger M., Rutherford P., and Gemmel L. Validation of a modified Early Warning Score in medical admissions. QJM 94 (2001) 521-526