Changes in spontaneous contractions of rat ileum by aflatoxin in vitro

Food and Chemical Toxicology

Volumn 46, Issue 6, 2008, Pages 2124-2127

  Gursoy, Nevcihan ^a   Sarac, Bulent ^a   Durmus, Nedim ^a   Parlak, Ahmet ^a   Yildirim, Sahin ^a   Kaya, Tijen ^a   Bagcivan, Ihsan ^a  

^a CUMHURIYET UNIVERSITY   (Turkey)

Author keywords

Aflatoxin; Amplitude; Frequency; Ileum

Indexed keywords

AFLATOXIN; ATROPINE; HEXAMETHONIUM CHLORIDE; TETRODOTOXIN;

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLINERGIC SYSTEM; CONTROLLED STUDY; GASTROINTESTINAL TOXICITY; ILEUM CONTRACTION; MALE; MOTONEURON; NERVE ENDING; NONHUMAN; RAT;

ACETYLCHOLINE; AFLATOXINS; ANALGESICS, OPIOID; ANIMALS; ATROPINE; DOSE-RESPONSE RELATIONSHIP, DRUG; GASTROINTESTINAL MOTILITY; HEXAMETHONIUM; ILEUM; ISOMETRIC CONTRACTION; MALE; MORPHINE; MUSCARINIC ANTAGONISTS; MUSCLE, SMOOTH; NICOTINIC ANTAGONISTS; RATS; RATS, WISTAR; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN;

ANIMALIA; ASPERGILLUS FLAVUS; ASPERGILLUS NOMIUS; ASPERGILLUS PARASITICUS; RATTUS;

EID: 42749086439     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2008.02.005     Document Type: Article

References (28)

1. Abdel-Haq H., Palmery M., Leone M.G., Saso L., and Silvestrini B. Relaxant effects of aflatoxins on isolated guinea pig trachea. Toxicological Sciences 55 (2000) 162-170
2. Abdel-Haq H., Palmery M., Leone M.G., Saso L., and Silvestrini B. Stimulation on guinea pig isolated atria by aflatoxins. Toxicology In Vitro 14 (2000) 193-197
3. Atroshi F., Rizzo A., Westermack T., and Ali-Vehmas T. Antioxidant nutrients and mycotoxins. Toxicology 180 (2002) 151-167
4. Aziz N.H., and Moussa L.A.A. Influence of gamma-radiation on mycotoxin producing moulds and mycotoxins in fruits. Food Control 13 (2002) 281-288 with permission from Elsevier
5. Bonsi P., Augusti-Tocco G., Palmery M., and Giorgi M. Aflatoxin B1 is an inhibitor of cyclic nucleotide phosphodiesterase activity. General Pharmacology 32 (1999) 615-619
6. Bortell R., Asquith R.L., Edds G.T., Simpson C.F., and Aller W.W. Acute experimentally induced aflatoxicosis in the weanling pony. American Journal of Veterinary Research 44 (1983) 2110-2114
7. Brown M.P., Brown-Jenco C.S., and Payne G.A. Genetic and molecular analysis of aflatoxin biosynthesis. Fungal Genetics and Biology 26 2 (1999) 81-98
8. CAST, 2003. Mycotoxins. Risks in plant, animal, and human systems. Task Force Report, No. 139. Council for Agricultural Science and Technology, Ames, Iowa.
9. Chao T.C., Maxwell S.M., and Wong S.Y. An outbreak of aflatoxicosis and boric acid poisoning in Malaysia: a clinical pathological study. Journal of Pathology 164 (1991) 225-233
10. Cook W.O., Richard J.L., Osweiler G.D., and Trampel D.W. Clinical and pathologic changes in acute bovine aflatoxicosis: rumen motility and tissue and fluid concentrations of aflatoxins B1 and M1. American Journal of Veterinary Research 47 (1986) 1817-1825
11. Creppy E.E. Update of survey, regulation and toxic effects of mycotoxins in Europe. Toxicology Letters 127 (2002) 19-28
12. 1-induced hepatic steatosis: role of carbonyl compounds and active diols on steatogenesis. Lancet 353 (1999) 747-748
13. Galvano F., Piva A., Ritieni A., and Galvano G. Dietary strategies to counteract the effects of mycotoxins: A review. Journal of Food Protection 64 1 (2001) 120-131
14. Guengerich F.P., Johnson W.W., Shimada T., Ueng Y.F., Yamazaki H., and Langouet S. Activation and detoxification of aflatoxin B1. Mutation Research 402 (1998) 121-128
15. Hussein H.S., and Brasel J.M. Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167 (2001) 101-134
16. Hussein H.S., and Brasel J.M. Toxicity, metabolism, and impact of mycotoxins on humans and animals. Toxicology 167 (2001) 101-134
17. IARC. IARC monographs on the evaluation of carcinogenic risks to humans. Some Naturally Occurring Substances: Food Items, Constituents, Heterocyclic Aromatic Amines, Mycotoxins vol. 56 (1993), International Agency for Research on Cancer, Lyon 249-395
18. Lougheed M.D., Roos J.O., Waddel W.R., and Munt P.W. Desquamative interstitial pneumonitis and diffuse alveolar damage in textile workers. Potential role of mycotoxins. Chest 108 (1995) 1196-1200
19. Luzi A., Cometa M.F., and Palmery M. Acute effects of aflatoxins on guinea pig isolated ileum. Toxicology In Vitro 16 (2002) 525-529
20. McLean M., and Dutton M.F. Cellular interactions and metabolism of aflatoxin: an update. Pharmacology and Therapeutics 65 (1995) 163-192
21. Oyelami O.A., Maxwell S.M., Adelusola K.A., Aladekoma T.A., and Oyelese A.O. Aflatoxins in the lungs of children with kwashiorkor and children with miscellaneous diseases in Nigeria. Journal of Toxicology and Environmental Health 51 (1997) 623-628
22. Park D.C. Controlling aflatoxin in food and feed. Food Technology 47 (1993) 92-96
23. Peraica M., Radiæ B., Luciæ A., and Pavloviæ M. Toxic effects of mycotoxins in humans. Bulletin of the World Health Organ 77 (1999) 754-766
24. Scheidegger K.A., and Payne G.A. Unlocking the Secrets Behind Secondary Metabolism: A Review of Aspergillus flavus from Pathogenicity to Functional Genomics. Toxin Reviews 22 2-3 (2003) 423-459
25. Steyn P.S. Mycotoxins, general view, chemistry and structure. Toxicology Letters 82/83 (1995) 843-851
26. Sweeney M.J., and Dobson A.D. Mycotoxin production by Aspergillus, Fusarium and Penicillium species. International Journal of Food Microbiology 43 3 (1998) 141-158
27. Tandon H.D., Tandon B.N., and Ramalingaswami V. Epidemic of toxic hepatitis in India of possible mycotoxic origin. Archives of Pathology & Laboratory Medicine 102 7 (1978) 372-376
28. Wood G.E. Mycotoxins in foods and feeds in the United States. Journal of Animal Science 70 12 (1992) 3941-3949